Mitochondrial translocation of cofilin is an early step in apoptosis induction BT Chua, C Volbracht, KO Tan, R Li, VC Yu, P Li Nature cell biology 5 (12), 1083-1089, 2003 | 363 | 2003 |
Identification of chelerythrine as an inhibitor of BclXL function SL Chan, MC Lee, KO Tan, LK Yang, ASY Lee, H Flotow, NY Fu, ... Journal of Biological Chemistry 278 (23), 20453-20456, 2003 | 230 | 2003 |
MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains KO Tan, KML Tan, SL Chan, KSY Yee, M Bévort, KC Ang, CY Victor Journal of Biological Chemistry 276 (4), 2802-2807, 2001 | 170 | 2001 |
MAP-1 is a mitochondrial effector of Bax KO Tan, NY Fu, SK Sukumaran, SL Chan, JH Kang, KL Poon, BS Chen, ... Proceedings of the National Academy of Sciences 102 (41), 14623-14628, 2005 | 150 | 2005 |
A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity KO Tan, KML Tan, CY Victor Journal of Biological Chemistry 274 (34), 23687-23690, 1999 | 73 | 1999 |
The Caenorhabditis elegansSex-determining Protein FEM-2 and Its Human Homologue, hFEM-2, Are Ca2+/Calmodulin-dependent Protein Kinase Phosphatases That Promote Apoptosis KML Tan, SL Chan, KO Tan, CY Victor Journal of Biological Chemistry 276 (47), 44193-44202, 2001 | 65 | 2001 |
F1Aα, a Death Receptor-binding Protein Homologous to theCaenorhabditis elegans Sex-determining Protein, FEM-1, Is a Caspase Substrate That Mediates Apoptosis SL Chan, KO Tan, L Zhang, KSY Yee, F Ronca, MY Chan, CY Victor Journal of Biological Chemistry 274 (45), 32461-32468, 1999 | 44 | 1999 |
PNMA family: Protein interaction network and cell signalling pathways implicated in cancer and apoptosis SW Pang, C Lahiri, CL Poh, KO Tan Cellular signalling 45, 54-62, 2018 | 33 | 2018 |
Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice. PCL Yee PTI, Tan SH, Ong KC, Tan KO, Wong KT, Hassan SS Scientific Report, 4805, 2019 | 32 | 2019 |
Distinct functional domains of PNMA5 mediate protein–protein interaction, nuclear localization, and apoptosis signaling in human cancer cells YH Lee, SW Pang, CL Poh, KO Tan Journal of cancer research and clinical oncology 142, 1967-1977, 2016 | 22 | 2016 |
Molecular characterization of avian muscle titin. KO Tan, GR Sater, AM Myers, RM Robson, TW Huiatt Journal of Biological Chemistry 268 (30), 22900-22907, 1993 | 21 | 1993 |
PNMA2 mediates heterodimeric interactions and antagonizes chemo-sensitizing activities mediated by members of PNMA family YH Lee, SW Pang, KO Tan Biochemical and Biophysical Research Communications 473 (1), 224-229, 2016 | 16 | 2016 |
Emerging strategies for sensitization of therapy resistant tumors toward cancer therapeutics by targeting the Bcl-2 family, TGF-β, Wnt/β-Catenin, RASSF and miRNA regulated … T Veerasamy, SE Simon, KO Tan The International Journal of Biochemistry & Cell Biology 137, 106016, 2021 | 15 | 2021 |
Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1 YH Lee, SW Pang, E Revai Lechtich, K Shah, SE Simon, S Ponnusamy, ... Journal of Cancer Research and Clinical Oncology 146, 1751-1764, 2020 | 15 | 2020 |
Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71 PTI Yee, KO Tan, I Othman, CL Poh Virology journal 13, 1-12, 2016 | 14 | 2016 |
Alpha‐Mangostin Activates MOAP‐1 Tumor Suppressor and Mitochondrial Signaling in MCF‐7 Human Breast Cancer Cells SE Simon, HS Lim, FA Jayakumar, EW Tan, KO Tan Evidence‐Based Complementary and Alternative Medicine 2022 (1), 7548191, 2022 | 12 | 2022 |
Human Embryonic Stem Cell‐Derived Neural Lineages as In Vitro Models for Screening the Neuroprotective Properties of Lignosus rhinocerus (Cooke) Ryvarden Y Yeo, JBL Tan, LW Lim, KO Tan, BC Heng, WL Lim BioMed Research International 2019 (1), 3126376, 2019 | 12 | 2019 |
Pluripotent human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy MS Yap, YQ Tang, Y Yeo, WL Lim, LW Lim, KO Tan, M Richards, I Othman, ... Virology Journal 13, 1-10, 2016 | 11 | 2016 |
Engineered Oncolytic Adenoviruses: An Emerging Approach for Cancer Therapy CLPKOT Ee Wern Tan, Noraini Abd-Aziz Pathogens 11 (10), 24, 2022 | 10* | 2022 |
New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family SE Simon, U Ahmed, SM Saad, A Anwar, KM Khan, EW Tan, KO Tan Bioorganic & Medicinal Chemistry Letters 67, 128731, 2022 | 9 | 2022 |