Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012 | 1992 | 2012 |
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway J Son, CA Lyssiotis, H Ying, X Wang, S Hua, M Ligorio, RM Perera, ... Nature 496 (7443), 101-105, 2013 | 1916 | 2013 |
Pancreatic cancers require autophagy for tumor growth S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ... Genes & development 25 (7), 717-729, 2011 | 1604 | 2011 |
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ... Nature 514 (7524), 628-632, 2014 | 1197 | 2014 |
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ... Science 318 (5848), 287-290, 2007 | 1111 | 2007 |
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion CM Sousa, DE Biancur, X Wang, CJ Halbrook, MH Sherman, LI Zhang, ... Nature 536 (7617), 479-483, 2016 | 994 | 2016 |
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Nature 455 (7216), 1129-1133, 2008 | 860 | 2008 |
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer A Kapoor, W Yao, H Ying, S Hua, A Liewen, Q Wang, Y Zhong, CJ Wu, ... Cell 158 (1), 185-197, 2014 | 704 | 2014 |
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine 25 (4), 628-640, 2019 | 581 | 2019 |
Genetics and biology of pancreatic ductal adenocarcinoma H Ying, P Dey, W Yao, AC Kimmelman, GF Draetta, A Maitra, RA DePinho Genes & development 30 (4), 355-385, 2016 | 567 | 2016 |
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis J Paik, Z Ding, R Narurkar, S Ramkissoon, F Muller, WS Kamoun, ... Cell stem cell 5 (5), 540-553, 2009 | 486 | 2009 |
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer J Hu, SS Hwang, M Liesa, B Gan, E Sahin, M Jaskelioff, Z Ding, H Ying, ... Cell 148 (4), 651-663, 2012 | 343 | 2012 |
MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein P Sdek, H Ying, DLF Chang, W Qiu, H Zheng, R Touitou, MJ Allday, ... Molecular cell 20 (5), 699-708, 2005 | 309 | 2005 |
PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas H Zheng, H Ying, R Wiedemeyer, H Yan, SN Quayle, EV Ivanova, JH Paik, ... Cancer cell 17 (5), 497-509, 2010 | 277 | 2010 |
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 253 | 2017 |
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB–cytokine network H Ying, KG Elpek, A Vinjamoori, SM Zimmerman, GC Chu, H Yan, ... Cancer discovery 1 (2), 158-169, 2011 | 234 | 2011 |
Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors N Currier, SE Solomon, EG Demicco, DLF Chang, M Farago, H Ying, ... Toxicologic pathology 33 (6), 726-737, 2005 | 217 | 2005 |
Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis N Santana-Codina, AA Roeth, Y Zhang, A Yang, O Mashadova, JM Asara, ... Nature communications 9 (1), 4945, 2018 | 199 | 2018 |
KRAS-related proteins in pancreatic cancer KM Mann, H Ying, J Juan, NA Jenkins, NG Copeland Pharmacology & therapeutics 168, 29-42, 2016 | 194 | 2016 |
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer AC Kimmelman, AF Hezel, AJ Aguirre, H Zheng, J Paik, H Ying, GC Chu, ... Proceedings of the National Academy of Sciences 105 (49), 19372-19377, 2008 | 186 | 2008 |