IFNα activates dormant haematopoietic stem cells in vivo MAG Essers, S Offner, WE Blanco-Bose, Z Waibler, U Kalinke, ... Nature 458 (7240), 904-908, 2009 | 1531 | 2009 |
Human haematopoietic stem cell lineage commitment is a continuous process L Velten, SF Haas, S Raffel, S Blaszkiewicz, S Islam, BP Hennig, C Hirche, ... Nature cell biology 19 (4), 271-281, 2017 | 972 | 2017 |
Functional interaction between β-catenin and FOXO in oxidative stress signaling MAG Essers, LMM de Vries-Smits, N Barker, PE Polderman, ... Science 308 (5725), 1181-1184, 2005 | 920 | 2005 |
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK MAG Essers, S Weijzen, AMM de Vries‐Smits, I Saarloos, ND de Ruiter, ... The EMBO journal 23 (24), 4802-4812, 2004 | 915 | 2004 |
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ... Nature 520 (7548), 549-552, 2015 | 655 | 2015 |
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ... Cell stem cell 15 (4), 507-522, 2014 | 584 | 2014 |
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors GJPL Kops, RH Medema, J Glassford, MAG Essers, PF Dijkers, PJ Coffer, ... Molecular and cellular biology 22 (7), 2025-2036, 2002 | 564 | 2002 |
Awakening dormant haematopoietic stem cells A Trumpp, M Essers, A Wilson Nature Reviews Immunology 10 (3), 201-209, 2010 | 529 | 2010 |
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ... Cell stem cell 17 (4), 422-434, 2015 | 456 | 2015 |
Dormant and self‐renewing hematopoietic stem cells and their niches A Wilson, GM Oser, M Jaworski, WE BLANCO‐BOSE, E Laurenti, ... Annals of the New York Academy of Sciences 1106 (1), 64-75, 2007 | 330 | 2007 |
Interaction of FOXO with β-catenin inhibits β-catenin/T cell factor activity D Hoogeboom, MAG Essers, PE Polderman, E Voets, LMM Smits, ... Journal of Biological Chemistry 283 (14), 9224-9230, 2008 | 329 | 2008 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 285 | 2017 |
Myc depletion induces a pluripotent dormant state mimicking diapause R Scognamiglio, N Cabezas-Wallscheid, MC Thier, S Altamura, A Reyes, ... Cell 164 (4), 668-680, 2016 | 265 | 2016 |
Targeting leukemic stem cells by breaking their dormancy MAG Essers, A Trumpp Molecular oncology 4 (5), 443-450, 2010 | 241 | 2010 |
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs M Pein, J Insua-Rodríguez, T Hongu, A Riedel, J Meier, L Wiedmann, ... Nature communications 11 (1), 1494, 2020 | 141 | 2020 |
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 115 | 2022 |
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene T Oskarsson, MAG Essers, N Dubois, S Offner, C Dubey, C Roger, ... Genes & development 20 (15), 2024-2029, 2006 | 104 | 2006 |
Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions M Weisser, UM Demel, S Stein, L Chen-Wichmann, F Touzot, G Santilli, ... Journal of Allergy and Clinical Immunology 138 (1), 219-228. e9, 2016 | 78 | 2016 |
The hematopoietic bone marrow niche ecosystem J Fröbel, T Landspersky, G Percin, C Schreck, S Rahmig, A Ori, D Nowak, ... Frontiers in cell and developmental biology 9, 705410, 2021 | 72 | 2021 |
Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo C Hirche, T Frenz, SF Haas, M Döring, K Borst, PK Tegtmeyer, I Brizic, ... Cell reports 19 (11), 2345-2356, 2017 | 71 | 2017 |