A specific amyloid-β protein assembly in the brain impairs memory S Lesné, MT Koh, L Kotilinek, R Kayed, CG Glabe, A Yang, M Gallagher, ... Nature 440 (7082), 352-357, 2006 | 3455 | 2006 |
Brain amyloid-β oligomers in ageing and Alzheimer’s disease SE Lesne, MA Sherman, M Grant, M Kuskowski, JA Schneider, ... Brain 136 (5), 1383-1398, 2013 | 514 | 2013 |
Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models IH Cheng, K Scearce-Levie, J Legleiter, JJ Palop, H Gerstein, N Bien-Ly, ... Journal of Biological Chemistry 282 (33), 23818-23828, 2007 | 504 | 2007 |
Amyloid oligomers: A joint experimental/computational perspective on Alzheimer’s disease, Parkinson’s disease, type II diabetes, and amyotrophic lateral sclerosis PH Nguyen, A Ramamoorthy, BR Sahoo, J Zheng, P Faller, JE Straub, ... Chemical reviews 121 (4), 2545-2647, 2021 | 479 | 2021 |
Soluble Aβ oligomer production and toxicity ME Larson, SE Lesné Journal of neurochemistry 120, 125-139, 2012 | 470 | 2012 |
The complex PrPc-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease M Larson, MA Sherman, F Amar, M Nuvolone, JA Schneider, DA Bennett, ... Journal of Neuroscience 32 (47), 16857-16871, 2012 | 329 | 2012 |
Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain C Ali, O Nicole, F Docagne, S Lesne, ET MacKenzie, A Nouvelot, ... Journal of Cerebral Blood Flow & Metabolism 20 (6), 956-966, 2000 | 311 | 2000 |
Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity LA Kotilinek, MA Westerman, Q Wang, K Panizzon, GP Lim, A Simonyi, ... Brain 131 (3), 651-664, 2008 | 290 | 2008 |
NMDA receptor activation inhibits α-secretase and promotes neuronal amyloid-β production S Lesné, C Ali, C Gabriel, N Croci, ET MacKenzie, CG Glabe, M Plotkine, ... Journal of Neuroscience 25 (41), 9367-9377, 2005 | 271 | 2005 |
Plaque-bearing mice with reduced levels of oligomeric amyloid-β assemblies have intact memory function S Lesné, L Kotilinek, KH Ashe Neuroscience 151 (3), 745-749, 2008 | 240 | 2008 |
Orally available compound prevents deficits in memory caused by the Alzheimer amyloid‐β oligomers M Townsend, JP Cleary, T Mehta, J Hofmeister, S Lesne, E O'Hare, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 205 | 2006 |
Cognitive effects of cell-derived and synthetically derived Aβ oligomers MN Reed, JJ Hofmeister, L Jungbauer, AT Welzel, C Yu, MA Sherman, ... Neurobiology of aging 32 (10), 1784-1794, 2011 | 173 | 2011 |
Transforming growth factor-β1 potentiates amyloid-β generation in astrocytes and in transgenic mice S Lesné, F Docagne, C Gabriel, G Liot, DK Lahiri, L Buée, L Plawinski, ... Journal of Biological Chemistry 278 (20), 18408-18418, 2003 | 162 | 2003 |
Transforming growth factor-β and ischemic brain injury A Buisson, S Lesne, F Docagne, C Ali, O Nicole, ET MacKenzie, D Vivien Cellular and molecular neurobiology 23, 539-550, 2003 | 153 | 2003 |
Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology ME Larson, MA Sherman, S Greimel, M Kuskowski, JA Schneider, ... Journal of Neuroscience 32 (30), 10253-10266, 2012 | 150 | 2012 |
β-amyloid modulation of synaptic transmission and plasticity DV Venkitaramani, J Chin, WJ Netzer, GK Gouras, S Lesne, R Malinow, ... Journal of Neuroscience 27 (44), 11832-11837, 2007 | 144 | 2007 |
Angiopoietin‐1‐induced phosphatidyl‐inositol 3‐kinase activation prevents neuronal apoptosis S Valable, A Bellail, S Lesne, G Liot, ET Mackenzie, D Vivien, ... The FASEB journal 17 (3), 1-19, 2003 | 140 | 2003 |
Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity H Ma, S Lesné, L Kotilinek, JV Steidl-Nichols, M Sherman, L Younkin, ... Proceedings of the National Academy of Sciences 104 (19), 8167-8172, 2007 | 138 | 2007 |
The amyloid-β oligomer Aβ* 56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation F Amar, MA Sherman, T Rush, M Larson, G Boyle, L Chang, J Götz, ... Science signaling 10 (478), eaal2021, 2017 | 116 | 2017 |
Oligomers of the amyloid-β protein disrupt working memory: confirmation with two behavioral procedures A Poling, K Morgan-Paisley, JJ Panos, EM Kim, E O’Hare, JP Cleary, ... Behavioural brain research 193 (2), 230-234, 2008 | 106 | 2008 |