Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond) U Lächelt, E Wagner Chemical reviews 115 (19), 11043-11078, 2015 | 616 | 2015 |
The current status of MOF and COF applications R Freund, O Zaremba, G Arnauts, R Ameloot, G Skorupskii, M Dincă, ... Angewandte Chemie International Edition 60 (45), 23975-24001, 2021 | 598 | 2021 |
The chemistry of reticular framework nanoparticles: MOF, ZIF, and COF materials E Ploetz, H Engelke, U Lächelt, S Wuttke Advanced Functional Materials 30 (41), 1909062, 2020 | 220 | 2020 |
Imparting functionality to MOF nanoparticles by external surface selective covalent attachment of polymers A Zimpel, T Preiß, R Röder, H Engelke, M Ingrisch, M Peller, JO Rädler, ... Chemistry of Materials 28 (10), 3318-3326, 2016 | 220 | 2016 |
Multifunctional efficiency: extending the concept of atom economy to functional nanomaterials R Freund, U Lächelt, T Gruber, B Rühle, S Wuttke ACS nano 12 (3), 2094-2105, 2018 | 219 | 2018 |
Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications R Ettlinger, U Lächelt, R Gref, P Horcajada, T Lammers, C Serre, ... Chemical Society Reviews 51 (2), 464-484, 2022 | 199 | 2022 |
Multifunctional nanoparticles by coordinative self-assembly of His-tagged units with metal–organic frameworks R Röder, T Preiß, P Hirschle, B Steinborn, A Zimpel, M Höhn, ... Journal of the American Chemical Society 139 (6), 2359-2368, 2017 | 194 | 2017 |
Polyplex evolution: understanding biology, optimizing performance A Hall, U Lächelt, J Bartek, E Wagner, SM Moghimi Molecular Therapy 25 (7), 1476-1490, 2017 | 187 | 2017 |
Nanosized multifunctional polyplexes for receptor-mediated siRNA delivery C Dohmen, D Edinger, T Fröhlich, L Schreiner, U Lächelt, C Troiber, ... ACS nano 6 (6), 5198-5208, 2012 | 177 | 2012 |
Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes U Lächelt, P Kos, FM Mickler, A Herrmann, EE Salcher, W Rödl, ... Nanomedicine: Nanotechnology, Biology and Medicine 10 (1), 35-44, 2014 | 158 | 2014 |
Defined folate-PEG-siRNA conjugates for receptor-specific gene silencing C Dohmen, T Fröhlich, U Lächelt, I Röhl, HP Vornlocher, P Hadwiger, ... Molecular Therapy-Nucleic Acids 1, 2012 | 154 | 2012 |
Solid-phase-assisted synthesis of targeting peptide–PEG–oligo (ethane amino) amides for receptor-mediated gene delivery I Martin, C Dohmen, C Mas-Moruno, C Troiber, P Kos, D Schaffert, ... Organic & biomolecular chemistry 10 (16), 3258-3268, 2012 | 100 | 2012 |
Coordinative binding of polymers to metal–organic framework nanoparticles for control of interactions at the biointerface A Zimpel, N Al Danaf, B Steinborn, J Kuhn, M Höhn, T Bauer, P Hirschle, ... ACS nano 13 (4), 3884-3895, 2019 | 94 | 2019 |
Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer P Kos, U Lächelt, A Herrmann, FM Mickler, M Döblinger, D He, ... Nanoscale 7 (12), 5350-5362, 2015 | 85 | 2015 |
Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand DJ Lee, E Kessel, D Edinger, D He, PM Klein, LV von Voithenberg, ... Biomaterials 77, 98-110, 2016 | 75 | 2016 |
Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots S Wang, C Li, M Qian, H Jiang, W Shi, J Chen, U Lächelt, E Wagner, W Lu, ... Biomaterials 141, 29-39, 2017 | 64 | 2017 |
Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP Y Lin, E Wagner, U Lächelt Biomaterials Science 10 (5), 1166-1192, 2022 | 61 | 2022 |
Combinatorial optimization of sequence-defined oligo (ethanamino) amides for folate receptor-targeted pDNA and siRNA delivery D He, K Müller, A Krhac Levacic, P Kos, U Lächelt, E Wagner Bioconjugate chemistry 27 (3), 647-659, 2016 | 60 | 2016 |
pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing X Liu, P Zhang, D He, W Rödl, T Preiß, JO Rädler, E Wagner, ... Biomacromolecules 17 (1), 173-182, 2016 | 54 | 2016 |
Antitumoral cascade-targeting ligand for IL-6 receptor-mediated gene delivery to glioma S Wang, S Reinhard, C Li, M Qian, H Jiang, Y Du, U Lächelt, W Lu, ... Molecular Therapy 25 (7), 1556-1566, 2017 | 53 | 2017 |