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Ammon E. Posey
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A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division
CR Chang, CM Manlandro, D Arnoult, J Stadler, AE Posey, RB Hill, ...
Journal of Biological Chemistry 285 (42), 32494-32503, 2010
1802010
Phase separation of intrinsically disordered proteins
AE Posey, AS Holehouse, RV Pappu
Methods in enzymology 611, 1-30, 2018
1372018
Arginine-enriched mixed-charge domains provide cohesion for nuclear speckle condensation
JA Greig, TA Nguyen, M Lee, AS Holehouse, AE Posey, RV Pappu, ...
Molecular cell 77 (6), 1237-1250. e4, 2020
1172020
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers
AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu
Journal of Biological Chemistry 293 (10), 3734-3746, 2018
972018
Self-assembly of block heterochiral peptides into helical tapes
TM Clover, CL O’Neill, R Appavu, G Lokhande, AK Gaharwar, AE Posey, ...
Journal of the American Chemical Society 142 (47), 19809-19813, 2020
432020
Inhibition of amyloid beta fibril formation by monomeric human transthyretin
K Garai, AE Posey, X Li, JN Buxbaum, RV Pappu
Protein Science 27 (7), 1252-1261, 2018
412018
Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate
I Seim, AE Posey, WT Snead, BM Stormo, D Klotsa, RV Pappu, ...
Proceedings of the National Academy of Sciences 119 (13), e2120799119, 2022
302022
Molecular motor Dnm1 synergistically induces membrane curvature to facilitate mitochondrial fission
MW Lee, EY Lee, GH Lai, NW Kennedy, AE Posey, W Xian, AL Ferguson, ...
ACS central science 3 (11), 1156-1167, 2017
282017
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu
Protein Engineering, Design and Selection 29 (9), 339-346, 2016
202016
Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils: Published as part of the Biochemistry virtual special …
M Kar, AE Posey, F Dar, AA Hyman, RV Pappu
Biochemistry 60 (43), 3213-3222, 2021
172021
Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
AE Posey, KM Ruff, JM Lalmansingh, TS Kandola, JJ Lange, R Halfmann, ...
Journal of molecular biology 433 (12), 166848, 2021
172021
A targeted mutation identified through pKa measurements indicates a postrecruitment role for Fis1 in yeast mitochondrial fission
M Koppenol-Raab, MC Harwig, AE Posey, JM Egner, KR MacKenzie, ...
Journal of Biological Chemistry 291 (39), 20329-20344, 2016
152016
Gold nanoshell assembly on a ferritin protein employed as a bio-template
JW Kim, AE Posey, GD Watt, SH Choi, PT Lillehei
Journal of Nanoscience and Nanotechnology 10 (3), 1771-1777, 2010
142010
Quantifying charge state heterogeneity for proteins with multiple ionizable residues
MJ Fossat, AE Posey, RV Pappu
Biophysical Journal 120 (24), 5438-5453, 2021
112021
Methods in Enzymology
AE Posey, AS Holehouse, RV Pappu
Elsevier, Inc 611, 1-30, 2018
112018
Quantifying coexistence concentrations in multi-component phase-separating systems using analytical HPLC
A Bremer, AE Posey, MB Borgia, WM Borcherds, M Farag, RV Pappu, ...
Biomolecules 12 (10), 1480, 2022
82022
Uncovering the contributions of charge regulation to the stability of single alpha helices
MJ Fossat, AE Posey, RV Pappu
ChemPhysChem 24 (7), e202200746, 2023
22023
Dynamical control enables the formation of demixed biomolecular condensates
AZ Lin, KM Ruff, AP Jalihal, F Dar, MR King, JM Lalmansingh, AE Posey, ...
bioRxiv, 2023.01. 04.522702, 2023
22023
A first glimpse of nucleation of phase transitions in living cells
AE Posey, RV Pappu
Molecular cell 71 (1), 1-3, 2018
22018
Basin mapping method for extracting comparative assessments of protein phase behavior from in vivo measurements
JM Lalmansingh, AE Posey, T Kandola, R Halfmann, RV Pappu
Biophysical Journal 118 (3), 538a, 2020
12020
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