Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease SP Yun, TI Kam, N Panicker, SM Kim, Y Oh, JS Park, SH Kwon, YJ Park, ... Nature medicine 24 (7), 931-938, 2018 | 887 | 2018 |
Alzheimer’s disease and Notch signaling HN Woo, JS Park, AR Gwon, TV Arumugam, DG Jo Biochemical and biophysical research communications 390 (4), 1093-1097, 2009 | 162 | 2009 |
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models G Bahn, JS Park, UJ Yun, YJ Lee, Y Choi, JS Park, SH Baek, BY Choi, ... Proceedings of the National Academy of Sciences 116 (25), 12516-12523, 2019 | 152 | 2019 |
Dextran sulfate nanoparticles as a theranostic nanomedicine for rheumatoid arthritis R Heo, DG You, W Um, KY Choi, S Jeon, JS Park, Y Choi, S Kwon, K Kim, ... Biomaterials 131, 15-26, 2017 | 150 | 2017 |
TNF-α gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis SJ Lee, A Lee, SR Hwang, JS Park, J Jang, MS Huh, DG Jo, SY Yoon, ... Molecular Therapy 22 (2), 397-408, 2014 | 150 | 2014 |
Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease DG Jo, TV Arumugam, HN Woo, JS Park, SC Tang, M Mughal, DH Hyun, ... Neurobiology of aging 31 (6), 917-925, 2010 | 124 | 2010 |
Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease JS Park, TI Kam, S Lee, H Park, Y Oh, SH Kwon, JJ Song, D Kim, H Kim, ... Acta neuropathologica communications 9 (1), 78, 2021 | 110 | 2021 |
Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy MJ Kim, JS Park, SJ Lee, J Jang, JS Park, SH Back, G Bahn, JH Park, ... Journal of Controlled Release 216, 140-148, 2015 | 110 | 2015 |
Oxidative lipid modification of nicastrin enhances amyloidogenic γ‐secretase activity in Alzheimer’s disease AR Gwon, JS Park, TV Arumugam, YK Kwon, SL Chan, SH Kim, SH Baik, ... Aging cell 11 (4), 559-568, 2012 | 103 | 2012 |
Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke YL Cheng, JS Park, S Manzanero, Y Choi, SH Baik, E Okun, ... Neurobiology of disease 62, 286-295, 2014 | 100 | 2014 |
Evidence that γ-secretase-mediated notch signaling induces neuronal cell death via the nuclear factor-κB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke TV Arumugam, YL Cheng, Y Choi, YH Choi, S Yang, YK Yun, JS Park, ... Molecular Pharmacology 80 (1), 23-31, 2011 | 98 | 2011 |
Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine NW Kim, MS Lee, KR Kim, JE Lee, K Lee, JS Park, Y Matsumoto, DG Jo, ... Journal of Controlled Release 179, 11-17, 2014 | 97 | 2014 |
Hyaluronan nanoparticles bearing γ-secretase inhibitor: In vivo therapeutic effects on rheumatoid arthritis R Heo, JS Park, HJ Jang, SH Kim, JM Shin, YD Suh, JH Jeong, DG Jo, ... Journal of controlled release 192, 295-300, 2014 | 93 | 2014 |
Inhibition of notch signalling ameliorates experimental inflammatory arthritis JS Park, SH Kim, K Kim, CH Jin, KY Choi, J Jang, Y Choi, AR Gwon, ... Annals of the rheumatic diseases 74 (1), 267-274, 2015 | 86 | 2015 |
Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells Y Oh, O Park, M Swierczewska, JP Hamilton, JS Park, TH Kim, SM Lim, ... Hepatology 64 (1), 209-223, 2016 | 80 | 2016 |
P in1 promotes neuronal death in stroke by stabilizing N otch intracellular domain SH Baik, M Fane, JH Park, YL Cheng, D Yang‐Wei Fann, UJ Yun, Y Choi, ... Annals of neurology 77 (3), 504-516, 2015 | 69 | 2015 |
Selenium attenuates Aβ production and Aβ-induced neuronal death AR Gwon, JS Park, JH Park, SH Baik, HY Jeong, DH Hyun, KW Park, ... Neuroscience letters 469 (3), 391-395, 2010 | 62 | 2010 |
Biodegradable DNA nanoparticles that provide widespread gene delivery in the brain P Mastorakos, E Song, C Zhang, S Berry, HW Park, YE Kim, JS Park, ... Small 12 (5), 678-685, 2016 | 56 | 2016 |
Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes … MK Shin, HG Kim, SH Baek, WR Jung, DI Park, JS Park, DG Jo, KL Kim Neurobiology of Aging 35 (5), 990-1001, 2014 | 56 | 2014 |
Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma JS Park, Y Oh, YJ Park, O Park, H Yang, S Slania, LK Hummers, AA Shah, ... Nature communications 10 (1), 1-11, 2019 | 38 | 2019 |