The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics S Elbaum-Garfinkle, Y Kim, K Szczepaniak, CCH Chen, CR Eckmann, ... Proceedings of the National Academy of Sciences 112 (23), 7189-7194, 2015 | 1133 | 2015 |
The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer RJA Bell, HT Rube, A Kreig, A Mancini, SD Fouse, RP Nagarajan, S Choi, ... Science 348 (6238), 1036-1039, 2015 | 574 | 2015 |
mRNA structure determines specificity of a polyQ-driven phase separation EM Langdon, Y Qiu, A Ghanbari Niaki, GA McLaughlin, CA Weidmann, ... Science 360 (6391), 922-927, 2018 | 464 | 2018 |
Cytosolic viral sensor RIG-I is a 5'-Triphosphate–dependent translocase on double-stranded RNA S Myong, S Cui, PV Cornish, A Kirchhofer, MU Gack, JU Jung, ... Science 323 (5917), 1070-1074, 2009 | 454 | 2009 |
Real-time observation of RecA filament dynamics with single monomer resolution C Joo, SA McKinney, M Nakamura, I Rasnik, S Myong, T Ha Cell 126 (3), 515-527, 2006 | 344 | 2006 |
Spring-loaded mechanism of DNA unwinding by hepatitis C virus NS3 helicase S Myong, MM Bruno, AM Pyle, T Ha Science 317 (5837), 513-516, 2007 | 335 | 2007 |
Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction MU Gack, A Kirchhofer, YC Shin, KS Inn, C Liang, S Cui, S Myong, T Ha, ... Proceedings of the National Academy of Sciences 105 (43), 16743-16748, 2008 | 307 | 2008 |
Repetitive shuttling of a motor protein on DNA S Myong, I Rasnik, C Joo, TM Lohman, T Ha Nature 437 (7063), 1321-1325, 2005 | 301 | 2005 |
Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity H Hwang, H Kim, S Myong Proceedings of the National Academy of Sciences 108 (18), 7414-7418, 2011 | 275 | 2011 |
TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A XR Ma, M Prudencio, Y Koike, SC Vatsavayai, G Kim, F Harbinski, ... Nature 603 (7899), 124-130, 2022 | 272 | 2022 |
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36 MC Chen, R Tippana, NA Demeshkina, P Murat, S Balasubramanian, ... Nature 558 (7710), 465-469, 2018 | 267 | 2018 |
Protein induced fluorescence enhancement (PIFE) for probing protein–nucleic acid interactions H Hwang, S Myong Chemical Society Reviews 43 (4), 1221-1229, 2014 | 231 | 2014 |
DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes I Rasnik, S Myong, W Cheng, TM Lohman, T Ha Journal of molecular biology 336 (2), 395-408, 2004 | 202 | 2004 |
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices E Lerner, A Barth, J Hendrix, B Ambrose, V Birkedal, SC Blanchard, ... Elife 10, e60416, 2021 | 191 | 2021 |
PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps J Park, S Myong, A Niedziela-Majka, KS Lee, J Yu, TM Lohman, T Ha Cell 142 (4), 544-555, 2010 | 187 | 2010 |
G-quadruplex conformation and dynamics are determined by loop length and sequence R Tippana, W Xiao, S Myong Nucleic acids research 42 (12), 8106-8114, 2014 | 172 | 2014 |
Oxidative guanine base damage regulates human telomerase activity E Fouquerel, J Lormand, A Bose, HT Lee, GS Kim, J Li, RW Sobol, ... Nature structural & molecular biology 23 (12), 1092-1100, 2016 | 170 | 2016 |
POT1-TPP1 regulates telomeric overhang structural dynamics H Hwang, N Buncher, PL Opresko, S Myong Structure 20 (11), 1872-1880, 2012 | 157 | 2012 |
Loss of dynamic RNA interaction and aberrant phase separation induced by two distinct types of ALS/FTD-linked FUS mutations AG Niaki, J Sarkar, X Cai, K Rhine, V Vidaurre, B Guy, M Hurst, JC Lee, ... Molecular cell 77 (1), 82-94. e4, 2020 | 139 | 2020 |
RNA droplets K Rhine, V Vidaurre, S Myong Annual review of biophysics 49 (1), 247-265, 2020 | 118 | 2020 |