Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study G Moussa, R Alaaeddine, LM Alaeddine, R Nassra, ASF Belal, A Ismail, ... European journal of medicinal chemistry 144, 635-650, 2018 | 70 | 2018 |
Expanding the anticancer potential of 1, 2, 3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases PA Elzahhar, SM Abd El Wahab, M Elagawany, H Daabees, ASF Belal, ... European Journal of Medicinal Chemistry 200, 112439, 2020 | 54 | 2020 |
Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones PA Elzahhar, R Alaaeddine, TM Ibrahim, R Nassra, A Ismail, BSK Chua, ... European journal of medicinal chemistry 167, 562-582, 2019 | 41 | 2019 |
Impaired endothelium-dependent hyperpolarization underlies endothelial dysfunction during early metabolic challenge: increased ROS generation and possible interference with NO … R Alaaeddine, MAW Elkhatib, A Mroueh, H Fouad, EI Saad, ... Journal of Pharmacology and Experimental Therapeutics 371 (3), 567-582, 2019 | 25 | 2019 |
The emerging role of proteomics in precision medicine: applications in neurodegenerative diseases and neurotrauma R Alaaeddine, M Fayad, E Nehme, HF Bahmad, F Kobeissy Personalised Medicine: Lessons from Neurodegeneration to Cancer, 59-70, 2017 | 20 | 2017 |
The emerging role of COX-2, 15-LOX and PPARγ in metabolic diseases and cancer: an introduction to novel multi-target directed ligands (MTDLs) RA Alaaeddine, PA Elzahhar, I AlZaim, W Abou-Kheir, ASF Belal, ... Current Medicinal Chemistry 28 (11), 2260-2300, 2021 | 19 | 2021 |
The pleiotropic effects of antithrombotic drugs in the metabolic–cardiovascular–neurodegenerative disease continuum: Impact beyond reduced clotting RA Alaaeddine, I AlZaim, SH Hammoud, A Arakji, AH Eid, ... Clinical Science 135 (8), 1015-1051, 2021 | 16 | 2021 |
Neuropathic pain: literature review and recommendations of potential phytotherapies K Raafat, R El-Haj, D Shoumar, R Alaaeddine, Y Fakhro, N Tawil, F Shaer, ... Pharmacognosy Journal 9 (4), 2017 | 13 | 2017 |
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: A novel therapeutic target in early endothelial dysfunction of metabolic disease RA Alaaeddine, A Mroueh, S Gust, AH Eid, F Plane, AF El-Yazbi Current opinion in pharmacology 45, 33-41, 2019 | 12 | 2019 |
Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones PA Elzahhar, RA Alaaeddine, R Nassra, A Ismail, HF Labib, MG Temraz, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 669-684, 2021 | 11 | 2021 |
Endothelial Dysfunction as a result of Hypercaloric Intake: Underlying Mechanism in Absence of Hyperglycemia R Alaaeddine, M El‐khateeb, EI Saad, HH Fouad, M El‐Sabban, F Plane, ... The FASEB Journal 32, 837.2-837.2, 2018 | 1 | 2018 |
Anti-inflammatory Approaches to Mitigate Endothelial Dysfuntion in Early Metabolic Impairment R Alaaeddine | | 2022 |
Synthesis, Docking Studies and Biological Evaluation of Triazole‐Thiazolidinedione/Rhodanine Hybrids Targeting Cyclooxygenase‐2, 5‐Lipoxygenase and Peroxisome proliferator … R Alaaeddine, P Elzahhar, A Belal, R Nassra, T Ibrahim, N Wallner, ... The FASEB Journal 32, lb634-lb634, 2018 | | 2018 |