Activation of the pro-drug ethionamide is regulated in mycobacteria AR Baulard, JC Betts, J Engohang-Ndong, S Quan, RA McAdam, ... Journal of Biological Chemistry 275 (36), 28326-28331, 2000 | 410 | 2000 |
Thiolactomycin and Related Analogues as Novel Anti-mycobacterial Agents Targeting KasA and KasB Condensing Enzymes inMycobacterium tuberculosis L Kremer, JD Douglas, AR Baulard, C Morehouse, MR Guy, D Alland, ... Journal of Biological Chemistry 275 (22), 16857-16864, 2000 | 325 | 2000 |
Tuberculosis: the drug development pipeline at a glance B Villemagne, C Crauste, M Flipo, AR Baulard, B Déprez, N Willand European journal of medicinal chemistry 51, 1-16, 2012 | 254 | 2012 |
Synthetic EthR inhibitors boost antituberculous activity of ethionamide N Willand, B Dirie, X Carette, P Bifani, A Singhal, M Desroses, F Leroux, ... Nature medicine 15 (5), 537-544, 2009 | 218 | 2009 |
EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator J Engohang‐Ndong, D Baillat, M Aumercier, F Bellefontaine, GS Besra, ... Molecular microbiology 51 (1), 175-188, 2004 | 212 | 2004 |
Cloning, nucleotide sequence and expression in Escherichia coli of a lipase gene from Bacillus subtilis 168 V Dartois, A Baulard, K Schanck, C Colson Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (3 …, 1992 | 210 | 1992 |
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis B Phetsuksiri, M Jackson, H Scherman, M McNeil, GS Besra, AR Baulard, ... Journal of Biological Chemistry 278 (52), 53123-53130, 2003 | 207 | 2003 |
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ... The American Journal of Human Genetics 100 (6), 865-884, 2017 | 189* | 2017 |
Green fluorescent protein as a new expression marker in mycobacteria L Kremer, A Baulard, J Estaquier, O Poulain‐Godefroy, C Locht Molecular Microbiology 17 (5), 913-922, 1995 | 184 | 1995 |
Direct measurement of hydrophobic forces on cell surfaces using AFM D Alsteens, E Dague, PG Rouxhet, AR Baulard, YF Dufrêne Langmuir 23 (24), 11977-11979, 2007 | 181 | 2007 |
Chemical force microscopy of single live cells E Dague, D Alsteens, JP Latgé, C Verbelen, D Raze, AR Baulard, ... Nano letters 7 (10), 3026-3030, 2007 | 171 | 2007 |
Organization of the mycobacterial cell wall: a nanoscale view D Alsteens, C Verbelen, E Dague, D Raze, AR Baulard, YF Dufrêne Pflügers Archiv-European Journal of Physiology 456, 117-125, 2008 | 170 | 2008 |
Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis B Phetsuksiri, AR Baulard, AM Cooper, DE Minnikin, JD Douglas, ... Antimicrobial agents and chemotherapy 43 (5), 1042-1051, 1999 | 161 | 1999 |
Molecular Genetics of para-Aminosalicylic Acid Resistance in Clinical Isolates and Spontaneous Mutants of Mycobacterium tuberculosis V Mathys, R Wintjens, P Lefevre, J Bertout, A Singhal, M Kiass, ... Antimicrobial agents and chemotherapy 53 (5), 2100-2109, 2009 | 159 | 2009 |
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis TM Walker, P Miotto, CU Köser, PW Fowler, J Knaggs, Z Iqbal, M Hunt, ... The Lancet Microbe 3 (4), e265-e273, 2022 | 156 | 2022 |
Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis F Frénois, J Engohang-Ndong, C Locht, AR Baulard, V Villeret Molecular cell 16 (2), 301-307, 2004 | 147 | 2004 |
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420 N Blondiaux, M Moune, M Desroses, R Frita, M Flipo, V Mathys, ... Science 355 (6330), 1206-1211, 2017 | 142 | 2017 |
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis SS Gurcha, AR Baulard, L Kremer, C Locht, DB Moody, W Muhlecker, ... Biochemical Journal 365 (2), 441-450, 2002 | 131 | 2002 |
Ethionamide boosters: synthesis, biological activity, and structure− activity relationships of a series of 1, 2, 4-oxadiazole EthR inhibitors M Flipo, M Desroses, N Lecat-Guillet, B Dirié, X Carette, F Leroux, ... Journal of Medicinal Chemistry 54 (8), 2994-3010, 2011 | 114 | 2011 |
Characterization of a putative α-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis L Kremer, SS Gurcha, P Bifani, PG Hitchen, A Baulard, HR Morris, A Dell, ... Biochemical Journal 363 (3), 437-447, 2002 | 113 | 2002 |