Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress S Prabakaran, JE Swatton, MM Ryan, SJ Huffaker, JTJ Huang, JL Griffin, ... Molecular psychiatry 9 (7), 684-697, 2004 | 1169 | 2004 |
GDF15 mediates the effects of metformin on body weight and energy balance AP Coll, M Chen, P Taskar, D Rimmington, S Patel, JA Tadross, I Cimino, ... Nature 578 (7795), 444-448, 2020 | 428 | 2020 |
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia E Holmes, TM Tsang, JTJ Huang, FM Leweke, D Koethe, CW Gerth, ... PLoS medicine 3 (8), e327, 2006 | 339 | 2006 |
Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis JD Chalmers, KL Moffitt, G Suarez-Cuartin, O Sibila, S Finch, E Furrie, ... American journal of respiratory and critical care medicine 195 (10), 1384-1393, 2017 | 312 | 2017 |
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder MJ Lan, GA McLoughlin, JL Griffin, TM Tsang, JTJ Huang, P Yuan, ... Molecular psychiatry 14 (3), 269-279, 2009 | 215 | 2009 |
Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia TJ Huang, SA Price, L Chilton, NA Calcutt, DR Tomlinson, A Verkhratsky, ... Diabetes 52 (8), 2129-2136, 2003 | 215 | 2003 |
Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis JTJ Huang, FM Leweke, D Oxley, L Wang, N Harris, D Koethe, CW Gerth, ... PLoS medicine 3 (11), e428, 2006 | 214 | 2006 |
Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues JTJ Huang, L Wang, S Prabakaran, M Wengenroth, HE Lockstone, ... Molecular psychiatry 13 (12), 1118-1128, 2008 | 177 | 2008 |
BRCA1 is a histone-H2A-specific ubiquitin ligase R Kalb, DL Mallery, C Larkin, JTJ Huang, K Hiom Cell reports 8 (4), 999-1005, 2014 | 171 | 2014 |
Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons TJ Huang, A Verkhratsky, P Fernyhough Molecular and Cellular Neuroscience 28 (1), 42-54, 2005 | 163 | 2005 |
DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing P Chakraborty, JTJ Huang, K Hiom Nature communications 9 (1), 4346, 2018 | 149 | 2018 |
The sputum microbiome, airway inflammation, and mortality in chronic obstructive pulmonary disease AJ Dicker, JTJ Huang, M Lonergan, HR Keir, CJ Fong, B Tan, AJ Cassidy, ... Journal of Allergy and Clinical Immunology 147 (1), 158-167, 2021 | 139 | 2021 |
Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study HR Keir, A Shoemark, AJ Dicker, L Perea, J Pollock, YH Giam, ... The lancet Respiratory medicine 9 (8), 873-884, 2021 | 135 | 2021 |
CSF metabolic and proteomic profiles in patients prodromal for psychosis JTJ Huang, FM Leweke, TM Tsang, D Koethe, L Kranaster, CW Gerth, ... PloS one 2 (8), e756, 2007 | 131 | 2007 |
Multispecies coexistence of trees in tropical forests: spatial signals of topographic niche differentiation increase with environmental heterogeneity C Brown, D Burslem, JB Illian, L Bao, W Brockelman, M Cao, LW Chang, ... Proceedings of the Royal Society B: Biological Sciences 280 (1764), 20130502, 2013 | 122 | 2013 |
Neonicotinoids target distinct nicotinic acetylcholine receptors and neurons, leading to differential risks to bumblebees C Moffat, ST Buckland, AJ Samson, R McArthur, V Chamosa Pino, ... Scientific reports 6 (1), 24764, 2016 | 117 | 2016 |
Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3 TJ Huang, NM Sayers, P Fernyhough, A Verkhratsky Diabetologia 45, 560-570, 2002 | 113 | 2002 |
Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans EV Knatko, SH Ibbotson, Y Zhang, M Higgins, JW Fahey, P Talalay, ... Cancer Prevention Research 8 (6), 475-486, 2015 | 110 | 2015 |
Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy P Fernyhough, TJ Huang, A Verkhratsky Journal of the Peripheral Nervous System 8 (4), 227-235, 2003 | 108 | 2003 |
Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris) C Moffat, JG Pacheco, S Sharp, AJ Samson, KA Bollan, J Huang, ... The FASEB Journal 29 (5), 2112, 2015 | 102 | 2015 |