A deliberate approach to screening for initial crystallization conditions of biological macromolecules JR Luft, RJ Collins, NA Fehrman, AM Lauricella, CK Veatch, GT DeTitta Journal of structural biology 142 (1), 170-179, 2003 | 390 | 2003 |
Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis N Galitsky, V Cody, A Wojtczak, D Ghosh, JR Luft, W Pangborn, L English Acta Crystallographica Section D: Biological Crystallography 57 (8), 1101-1109, 2001 | 285 | 2001 |
Structures of human transthyretin complexed with thyroxine at 2.0 Å resolution and 3', 5'-dinitro-N-acetyl-L-thyronine at 2.2 Å resolution A Wojtczak, V Cody, JR Luft, W Pangborn Acta Crystallographica Section D: Biological Crystallography 52 (4), 758-765, 1996 | 242 | 1996 |
Device for growing crystals GT DeTitta, JR Luft US Patent 5,400,741, 1995 | 204 | 1995 |
Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data WN Price Ii, Y Chen, SK Handelman, H Neely, P Manor, R Karlin, R Nair, ... Nature biotechnology 27 (1), 51-57, 2009 | 190 | 2009 |
Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22: Kinetics, crystallography, and potential as selectable markers (∗) WS Lewis, V Cody, N Galitsky, JR Luft, W Pangborn, SK Chunduru, ... Journal of Biological Chemistry 270 (10), 5057-5064, 1995 | 159 | 1995 |
A method to produce microseed stock for use in the crystallization of biological macromolecules JR Luft, GT DeTitta Acta Crystallographica Section D: Biological Crystallography 55 (5), 988-993, 1999 | 155 | 1999 |
Macromolecular crystallization in a high throughput laboratory—the search phase JR Luft, J Wolfley, I Jurisica, J Glasgow, S Fortier, GT DeTitta Journal of Crystal Growth 232 (1-4), 591-595, 2001 | 128 | 2001 |
Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal … V Cody, JR Luft, W Pangborn Acta Crystallographica D Biological Crystallography 61 (2), 147-55, 2005 | 125 | 2005 |
Mechanism of molecular recognition. Structural aspects of 3, 3'-diiodo-L-thyronine binding to human serum transthyretin. A Wojtczak, J Luft, V Cody Journal of Biological Chemistry 267 (1), 353-357, 1992 | 101 | 1992 |
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies TL Arakaki, FS Buckner, JR Gillespie, NA Malmquist, MA Phillips, ... Molecular microbiology 68 (1), 37-50, 2008 | 98 | 2008 |
What’s in a drop? Correlating observations and outcomes to guide macromolecular crystallization experiments JR Luft, JR Wolfley, EH Snell Crystal growth & design 11 (3), 651-663, 2011 | 96 | 2011 |
Crystallization screening: the influence of history on current practice JR Luft, J Newman, EH Snell Acta Crystallographica Section F: Structural Biology Communications 70 (7 …, 2014 | 93 | 2014 |
Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor … PW Gangjee A, Vidwans AP, Vasudevan A, Queener SF, Kisliuk RL, Cody V, Li R ... Journal of Medicinal Chemistry 41 (18), 3426-34, 1998 | 90 | 1998 |
Small angle X‐ray scattering as a complementary tool for high‐throughput structural studies TD Grant, JR Luft, JR Wolfley, H Tsuruta, A Martel, GT Montelione, ... Biopolymers 95 (8), 517-530, 2011 | 88 | 2011 |
Ligand-Induced Conformational Changes in the Crystal Structures of Pneumocystis carinii Dihydrofolate Reductase Complexes with Folate and NADP+ , V Cody, N Galitsky, D Rak, JR Luft, W Pangborn, SF Queener Biochemistry 38 (14), 4303-4312, 1999 | 86 | 1999 |
Automatic classification of sub-microlitre protein-crystallization trials in 1536-well plates CA Cumbaa, A Lauricella, N Fehrman, C Veatch, R Collins, JR Luft, ... Acta Crystallographica Section D: Biological Crystallography 59 (9), 1619-1627, 2003 | 85 | 2003 |
Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions SK Chunduru, V Cody, JR Luft, W Pangborn, JR Appleman, RL Blakley Journal of Biological Chemistry 269 (13), 9547-9555, 1994 | 85 | 1994 |
Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 Å resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two … A Wojtczak, V Cody, JR Luft, W Pangborn Acta Crystallographica Section D: Biological Crystallography 57 (8), 1061-1070, 2001 | 83 | 2001 |
[7] Kinetic aspects of macromolecular crystallization JR Luft, GT Detitta Methods in enzymology 276, 110-131, 1997 | 80 | 1997 |