mTOR signaling in growth control and disease M Laplante, DM Sabatini cell 149 (2), 274-293, 2012 | 9388 | 2012 |
mTOR signaling at a glance M Laplante, DM Sabatini Journal of cell science 122 (20), 3589-3594, 2009 | 2828 | 2009 |
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival TR Peterson, M Laplante, CC Thoreen, Y Sancak, SA Kang, WM Kuehl, ... Cell 137 (5), 873-886, 2009 | 1588 | 2009 |
Obesity-associated improvements in metabolic profile through expansion of adipose tissue JY Kim, E Van De Wall, M Laplante, A Azzara, ME Trujillo, SM Hofmann, ... The Journal of clinical investigation 117 (9), 2621-2637, 2007 | 1587 | 2007 |
Regulation of mTORC1 and its impact on gene expression at a glance M Laplante, DM Sabatini Journal of cell science 126 (8), 1713-1719, 2013 | 754 | 2013 |
An emerging role of mTOR in lipid biosynthesis M Laplante, DM Sabatini Current biology 19 (22), R1046-R1052, 2009 | 737 | 2009 |
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity TP Combs, UB Pajvani, AH Berg, Y Lin, LA Jelicks, M Laplante, ... Endocrinology 145 (1), 367-383, 2004 | 712 | 2004 |
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing S Sengupta, TR Peterson, M Laplante, S Oh, DM Sabatini Nature 468 (7327), 1100-1104, 2010 | 684 | 2010 |
mTOR signaling M Laplante, DM Sabatini Cold Spring Harbor perspectives in biology 4 (2), a011593, 2012 | 349 | 2012 |
The roles of mTOR complexes in lipid metabolism A Caron, D Richard, M Laplante Annual review of nutrition 35, 321-348, 2015 | 296 | 2015 |
Connecting mTORC1 signaling to SREBP-1 activation I Bakan, M Laplante Current opinion in lipidology 23 (3), 226-234, 2012 | 285 | 2012 |
In vivo measurement of energy substrate contribution to cold‐induced brown adipose tissue thermogenesis SM Labbé, A Caron, I Bakan, M Laplante, AC Carpentier, R Lecomte, ... The FASEB Journal 29 (5), 2046-2058, 2015 | 244 | 2015 |
PPAR-γ Activation Mediates Adipose Depot− Specific Effects on Gene Expression and Lipoprotein Lipase Activity: Mechanisms for Modulation of Postprandial Lipemia and … M Laplante, H Sell, KL MacNaul, D Richard, JP Berger, Y Deshaies Diabetes 52 (2), 291-299, 2003 | 197 | 2003 |
A comparative perspective on lipid storage in animals K Birsoy, WT Festuccia, M Laplante Journal of cell science 126 (7), 1541-1552, 2013 | 176 | 2013 |
PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control WT Festuccia, M Laplante, M Berthiaume, Y Gelinas, Y Deshaies Diabetologia 49, 2427-2436, 2006 | 176 | 2006 |
A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver A Sood, DV Jeyaraju, J Prudent, A Caron, P Lemieux, HM McBride, ... Proceedings of the National Academy of Sciences 111 (45), 16017-16022, 2014 | 172 | 2014 |
Mechanisms of the depot specificity of peroxisome proliferator–activated receptor γ action on adipose tissue metabolism M Laplante, WT Festuccia, G Soucy, Y Gélinas, J Lalonde, JP Berger, ... Diabetes 55 (10), 2771-2778, 2006 | 166 | 2006 |
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway M Carbonneau, L M. Gagné, ME Lalonde, MA Germain, A Motorina, ... Nature communications 7 (1), 12700, 2016 | 163 | 2016 |
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis M Laplante, DM Sabatini Proceedings of the National Academy of Sciences 107 (8), 3281-3282, 2010 | 157 | 2010 |
Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status WT Festuccia, S Oztezcan, M Laplante, M Berthiaume, C Michel, S Dohgu, ... Endocrinology 149 (5), 2121-2130, 2008 | 150 | 2008 |