Tear cathepsin S as a candidate biomarker for Sjögren's syndrome SF Hamm‐Alvarez, SR Janga, MC Edman, S Madrigal, M Shah, ... Arthritis & Rheumatology 66 (7), 1872-1881, 2014 | 126 | 2014 |
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome M Shah, MC Edman, SR Janga, P Shi, J Dhandhukia, S Liu, SG Louie, ... Journal of controlled release 171 (3), 269-279, 2013 | 119 | 2013 |
Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse X Li, K Wu, M Edman, K Schenke-Layland, M MacVeigh-Aloni, SR Janga, ... Investigative ophthalmology & visual science 51 (10), 5019-5029, 2010 | 77 | 2010 |
Rapamycin eye drops suppress lacrimal gland inflammation in a murine model of Sjögren's syndrome M Shah, MC Edman, SR Janga, F Yarber, Z Meng, W Klinngam, ... Investigative ophthalmology & visual science 58 (1), 372-385, 2017 | 67 | 2017 |
Oligomeric α-synuclein is increased in basal tears of Parkinson’s patients SF Hamm-Alvarez, CT Okamoto, SR Janga, D Feigenbaum, MC Edman, ... Biomarkers in medicine 13 (11), 941-952, 2019 | 59 | 2019 |
Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients MC Edman, SR Janga, Z Meng, M Bechtold, AF Chen, C Kim, L Naman, ... Scientific reports 8 (1), 11044, 2018 | 59 | 2018 |
Delivery of Bone Marrow‐Derived Mesenchymal Stem Cells Improves Tear Production in a Mouse Model of Sjögren’s Syndrome HS Aluri, M Samizadeh, MC Edman, DR Hawley, HL Armaos, SR Janga, ... Stem cells international 2017 (1), 3134543, 2017 | 56 | 2017 |
Myoepithelial cell-driven acini contraction in response to oxytocin receptor stimulation is impaired in lacrimal glands of Sjögren’s syndrome animal models D Hawley, X Tang, T Zyrianova, M Shah, S Janga, A Letourneau, ... Scientific Reports 8 (1), 9919, 2018 | 40 | 2018 |
Inhibition of cathepsin S reduces lacrimal gland inflammation and increases tear flow in a mouse model of Sjögren’s syndrome W Klinngam, SR Janga, C Lee, Y Ju, F Yarber, M Shah, H Guo, D Wang, ... Scientific reports 9 (1), 9559, 2019 | 34 | 2019 |
Levels of oligomeric α-Synuclein in reflex tears distinguish Parkinson's disease patients from healthy controls SF Hamm-Alvarez, SR Janga, MC Edman, D Feigenbaum, D Freire, ... Biomarkers in medicine 13 (17), 1447-1457, 2019 | 32 | 2019 |
A novel elastin-like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome H Guo, C Lee, M Shah, SR Janga, MC Edman, W Klinngam, ... Journal of controlled release 292, 183-195, 2018 | 31 | 2018 |
Cathepsin S alters the expression of pro-inflammatory cytokines and MMP-9, partially through protease—activated receptor-2, in human corneal epithelial cells W Klinngam, R Fu, SR Janga, MC Edman, SF Hamm-Alvarez International Journal of Molecular Sciences 19 (11), 3530, 2018 | 28 | 2018 |
Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren’s Syndrome SR Janga, M Shah, Y Ju, Z Meng, MC Edman, SF Hamm-Alvarez Biomarkers 24 (1), 91-102, 2019 | 21 | 2019 |
Tears–more to them than meets the eye: why tears are a good source of biomarkers in Parkinson's disease MC Edman, SR Janga, SS Kakan, CT Okamoto, D Freire, D Feigenbaum, ... Biomarkers in medicine 14 (2), 151-163, 2020 | 20 | 2020 |
Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model R Fu, H Guo, S Janga, M Choi, W Klinngam, MC Edman, ... Scientific Reports 10 (1), 1455, 2020 | 19 | 2020 |
NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis Y Ju, SR Janga, W Klinngam, JA MacKay, D Hawley, D Zoukhri, ... Experimental eye research 176, 243-251, 2018 | 19 | 2018 |
Berunda polypeptides: biheaded rapamycin carriers for subcutaneous treatment of autoimmune dry eye disease C Lee, H Guo, W Klinngam, SR Janga, F Yarber, S Peddi, MC Edman, ... Molecular pharmaceutics 16 (7), 3024-3039, 2019 | 16 | 2019 |
Small RNA deep sequencing identifies a unique miRNA signature released in serum exosomes in a mouse model of Sjögren's syndrome SS Kakan, SR Janga, B Cooperman, DW Craig, MC Edman, CT Okamoto, ... Frontiers in Immunology 11, 1475, 2020 | 13 | 2020 |
Molecular targeting of immunosuppressants using a bifunctional elastin-like polypeptide Y Ju, H Guo, F Yarber, MC Edman, S Peddi, SR Janga, JA MacKay, ... Bioconjugate chemistry 30 (9), 2358-2372, 2019 | 11 | 2019 |
Tear proteins as possible biomarkers for Parkinson’s disease (S3. 006) D Feigenbaum, M Lew, S Janga, MK Shah, W Mack, C Okamoto, ... Neurology 90 (15_supplement), S3. 006, 2018 | 9 | 2018 |