New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model AB Kleist, AE Getschman, JJ Ziarek, AM Nevins, PA Gauthier, A Chevigné, ... Biochemical pharmacology 114, 53-68, 2016 | 141 | 2016 |
Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors M Szpakowska, V Fievez, K Arumugan, N Van Nuland, JC Schmit, ... Biochemical pharmacology 84 (10), 1366-1380, 2012 | 109 | 2012 |
The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides M Meyrath, M Szpakowska, J Zeiner, L Massotte, MP Merz, T Benkel, ... Nature communications 11 (1), 3033, 2020 | 102 | 2020 |
A novel ACKR2-dependent role of fibroblast-derived CXCL14 in epithelial-to-mesenchymal transition and metastasis of breast cancer E Sjöberg, M Meyrath, L Milde, M Herrera, J Lövrot, D Hägerstrand, ... Clinical cancer research 25 (12), 3702-3717, 2019 | 92 | 2019 |
The distinct roles of CXCR3 variants and their ligands in the tumor microenvironment N Reynders, D Abboud, A Baragli, MZ Noman, B Rogister, SP Niclou, ... Cells 8 (6), 613, 2019 | 79 | 2019 |
New Integrative Method To Generate Bacillus subtilis Recombinant Strains Free of Selection Markers A Brans, P Filée, A Chevigné, A Claessens, B Joris Applied and environmental microbiology 70 (12), 7241-7250, 2004 | 68 | 2004 |
Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3 M Szpakowska, AM Nevins, M Meyrath, D Rhainds, T D'huys, ... British journal of pharmacology 175 (9), 1419-1438, 2018 | 57 | 2018 |
Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds E Wouters, J Walraed, MJ Robertson, M Meyrath, M Szpakowska, ... ACS pharmacology & translational science 3 (2), 285-295, 2019 | 54 | 2019 |
Emerging roles of the protease allergen Der p 1 in house dust mite–induced airway inflammation A Chevigné, A Jacquet Journal of Allergy and Clinical Immunology 142 (2), 398-400, 2018 | 54 | 2018 |
Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus J Herman, N Thelen, N Smargiasso, AC Mailleux, A Luxen, M Cloes, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (3), 1117-1124, 2014 | 46 | 2014 |
Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7 M Szpakowska, N Dupuis, A Baragli, M Counson, J Hanson, J Piette, ... Biochemical Pharmacology 114, 14-21, 2016 | 45 | 2016 |
Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet ME Dumez, J Herman, V Campizi, M Galleni, A Jacquet, A Chevigné Frontiers in immunology 5, 138, 2014 | 44 | 2014 |
Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody JS Sohier, C Laurent, A Chevigné, E Pardon, V Srinivasan, U Wernery, ... Biochemical Journal 450 (3), 477-486, 2013 | 43 | 2013 |
GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 D Abboud, AF Daly, N Dupuis, MA Bahri, A Inoue, A Chevigné, F Ectors, ... Nature communications 11 (1), 4752, 2020 | 42 | 2020 |
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and … M Szpakowska, M Meyrath, N Reynders, M Counson, J Hanson, ... Biochemical Pharmacology 153, 299-309, 2018 | 37 | 2018 |
vCCL2/vMIP-II, the viral master KEYmokine M Szpakowska, A Chevigné Journal of Leucocyte Biology 99 (6), 893-900, 2016 | 35 | 2016 |
Engineering and screening the N-terminus of chemokines for drug discovery A Chevigné, V Fievez, JC Schmit, S Deroo Biochemical pharmacology 82 (10), 1438-1456, 2011 | 34 | 2011 |
Activation of the orphan G protein–coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment N Dupuis, C Laschet, D Franssen, M Szpakowska, J Gilissen, P Geubelle, ... Molecular Pharmacology 91 (6), 595-608, 2017 | 33 | 2017 |
Phages and HIV-1: From display to interplay S Delhalle, JC Schmit, A Chevigné International Journal of Molecular Sciences 13 (4), 4727-4794, 2012 | 33 | 2012 |
β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells RS Haider, ESF Matthees, J Drube, M Reichel, U Zabel, A Inoue, ... Nature Communications 13 (1), 5638, 2022 | 32 | 2022 |