关注
Ben Gu
Ben Gu
The Innate Phagocytosis Laboratory
在 florey.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
A systemic view of Alzheimer disease—insights from amyloid-β metabolism beyond the brain
J Wang, BJ Gu, CL Masters, YJ Wang
Nature reviews neurology 13 (10), 612-623, 2017
8292017
A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor
BJ Gu, W Zhang, RA Worthington, R Sluyter, P Dao-Ung, S Petrou, ...
Journal of Biological Chemistry 276 (14), 11135-11142, 2001
4122001
Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors
BJ Gu, WY Zhang, LJ Bendall, IP Chessell, GN Buell, JS Wiley
American Journal of Physiology-Cell Physiology 279 (4), C1189-C1197, 2000
2732000
The human P2X7 receptor and its role in innate immunity
JS Wiley, R Sluyter, BJ Gu, L Stokes, SJ Fuller
Tissue antigens 78 (5), 321-332, 2011
2512011
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
ML Smart, B Gu, RG Panchal, J Wiley, B Cromer, DA Williams, S Petrou
Journal of Biological Chemistry 278 (10), 8853-8860, 2003
2382003
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor
JS Wiley, LP Dao-Ung, C Li, AN Shemon, BJ Gu, ML Smart, SJ Fuller, ...
Journal of Biological Chemistry 278 (19), 17108-17113, 2003
2332003
Adenosine triphosphate–induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases
B Gu, LJ Bendall, JS Wiley
Blood, The Journal of the American Society of Hematology 92 (3), 946-951, 1998
2311998
Two haplotypes of the P2X7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion
L Stokes, SJ Fuller, R Sluyter, KK Skarratt, BJ Gu, JS Wiley
The FASEB Journal 24 (8), 2916-2927, 2010
2132010
A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages
AN Shemon, R Sluyter, SL Fernando, AL Clarke, LP Dao-Ung, KK Skarratt, ...
Journal of Biological Chemistry 281 (4), 2079-2086, 2006
2112006
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study
JS Wiley, LP Dao-Ung, BJ Gu, R Sluyter, AN Shemon, C Li, J Taper, ...
The Lancet 359 (9312), 1114-1119, 2002
2102002
An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor
BJ Gu, R Sluyter, KK Skarratt, AN Shemon, LP Dao-Ung, SJ Fuller, ...
Journal of Biological Chemistry 279 (30), 31287-31295, 2004
1942004
Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor
BJ Gu, JS Wiley
Blood 107 (12), 4946-4953, 2006
1882006
Genetics of the P2X7 receptor and human disease
SJ Fuller, L Stokes, KK Skarratt, BJ Gu, JS Wiley
Purinergic signalling 5, 257-262, 2009
1592009
The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP
BJ Gu, BM Saunders, C Jursik, JS Wiley
Blood, The Journal of the American Society of Hematology 115 (8), 1621-1631, 2010
1322010
P2X7 is a scavenger receptor for apoptotic cells in the absence of its ligand, extracellular ATP
BJ Gu, BM Saunders, S Petrou, JS Wiley
The Journal of Immunology 187 (5), 2365-2375, 2011
1122011
Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation
BJ Gu, C Rathsam, L Stokes, AB McGeachie, JS Wiley
American Journal of Physiology-Cell Physiology 297 (2), C430-C439, 2009
1062009
A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age‐related macular degeneration
BJ Gu, PN Baird, KA Vessey, KK Skarratt, EL Fletcher, SJ Fuller, ...
The FASEB Journal 27 (4), 1479-1487, 2013
842013
A 5′ intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian population
KK Skarratt, SJ Fuller, R Sluyter, LP Dao-Ung, BJ Gu, JS Wiley
FEBS letters 579 (12), 2675-2678, 2005
842005
Point mutations confer loss of ATP-induced human P2X7 receptor function
RA Worthington, ML Smart, BJ Gu, DA Williams, S Petrou, JS Wiley, ...
FEBS letters 512 (1-3), 43-46, 2002
832002
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis
BJ Gu, J Field, S Dutertre, A Ou, TJ Kilpatrick, J Lechner-Scott, R Scott, ...
Human molecular genetics 24 (19), 5644-5654, 2015
722015
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