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Michael Brunsteiner
Michael Brunsteiner
celeris therapeutics gmbh
在 celeristx.com 的电子邮件经过验证 - 首页
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引用次数
引用次数
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5-tert-butyl-N-pyrazol-4-yl-4, 5, 6, 7-tetrahydrobenzo [d] isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase …
S Velaparthi, M Brunsteiner, R Uddin, B Wan, SG Franzblau, PA Petukhov
Journal of medicinal chemistry 51 (7), 1999-2002, 2008
1462008
Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole-and pyrazole-based histone deacetylase probes
R Neelarapu, DL Holzle, S Velaparthi, H Bai, M Brunsteiner, SY Blond, ...
Journal of medicinal chemistry 54 (13), 4350-4364, 2011
1242011
Toward a molecular understanding of crystal agglomeration
M Brunsteiner, AG Jones, F Pratola, SL Price, SJR Simons
Crystal growth & design 5 (1), 3-16, 2005
1042005
Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors
B He, S Velaparthi, G Pieffet, C Pennington, A Mahesh, DL Holzle, ...
Journal of medicinal chemistry 52 (22), 7003-7013, 2009
612009
Morphologies of organic crystals: sensitivity of attachment energy predictions to the model intermolecular potential
M Brunsteiner, SL Price
Crystal Growth & Design 1 (6), 447-453, 2001
582001
Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid
T Eixelsberger, S Sykora, S Egger, M Brunsteiner, KL Kavanagh, ...
Journal of biological chemistry 287 (37), 31349-31358, 2012
482012
Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr215 in Aerococcus viridans lactate oxidase
T Stoisser, M Brunsteiner, DK Wilson, B Nidetzky
Scientific reports 6 (1), 27892, 2016
462016
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors
IT Schiefer, S Tapadar, V Litosh, M Siklos, R Scism, GT Wijewickrama, ...
Journal of medicinal chemistry 56 (15), 6054-6068, 2013
392013
Tribo-charging behaviour of inhalable mannitol blends with salbutamol sulphate
S Zellnitz, JT Pinto, M Brunsteiner, H Schröttner, J Khinast, A Paudel
Pharmaceutical research 36, 1-11, 2019
242019
Relative contributions of solubility and mobility to the stability of amorphous solid dispersions of poorly soluble drugs: A molecular dynamics simulation study
M Brunsteiner, J Khinast, A Paudel
Pharmaceutics 10 (3), 101, 2018
232018
Drug–excipient interactions in the solid state: The role of different stress factors
C Gressl, M Brunsteiner, A Davis, M Landis, K Pencheva, G Scrivens, ...
Molecular Pharmaceutics 14 (12), 4560-4571, 2017
232017
Influence of the treatment of electrostatic interactions on the results of free energy calculations of dipolar systems
M Brunsteiner, S Boresch
The Journal of Chemical Physics 112 (16), 6953-6955, 2000
232000
Insights from comprehensive multiple receptor docking to HDAC8
M Brunsteiner, PA Petukhov
Journal of molecular modeling 18, 3927-3939, 2012
222012
Prediction of drug-packaging interactions via molecular dynamics (MD) simulations
P Feenstra, M Brunsteiner, J Khinast
International journal of pharmaceutics 431 (1-2), 26-32, 2012
182012
Structure based descriptors for the estimation of colloidal interactions and protein aggregation propensities
M Brunsteiner, M Flock, B Nidetzky
PLoS One 8 (4), e59797, 2013
172013
Photoreactive “nanorulers” detect a novel conformation of full length HDAC3-SMRT complex in solution
H Abdelkarim, M Brunsteiner, R Neelarapu, H Bai, A Madriaga, ...
ACS chemical biology 8 (11), 2538-2549, 2013
142013
Solid-state reactivity of mechano-activated simvastatin: atypical relation to powder crystallinity
D Modhave, P Laggner, M Brunsteiner, A Paudel
Journal of Pharmaceutical Sciences 108 (10), 3272-3280, 2019
132019
Forced solid-state oxidation studies of nifedipine-PVP amorphous solid dispersion
I Saraf, R Roskar, D Modhave, M Brunsteiner, A Karn, D Neshchadin, ...
Molecular Pharmaceutics 19 (2), 568-583, 2022
112022
Bayesian optimization for ternary complex prediction (BOTCP)
A Rao, TM Tunjic, M Brunsteiner, M Müller, H Fooladi, C Gasbarri, ...
Artificial Intelligence in the Life Sciences 3, 100072, 2023
102023
Role of crystal disorder and mechanoactivation in solid-state stability of pharmaceuticals
J Iyer, M Brunsteiner, D Modhave, A Paudel
Journal of Pharmaceutical Sciences 112 (6), 1539-1565, 2023
102023
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