Stereoselective block of hERG channel by (S)‐methadone and QT interval prolongation in CYP2B6 slow metabolizers CB Eap, S Crettol, JS Rougier, J Schläpfer, LS Grilo, JJ Déglon, J Besson, ... Clinical Pharmacology & Therapeutics 81 (5), 719-728, 2007 | 333 | 2007 |
Cardiac sodium channel Nav1. 5 is regulated by a multiprotein complex composed of syntrophins and dystrophin B Gavillet, JS Rougier, AA Domenighetti, R Behar, C Boixel, P Ruchat, ... Circulation research 99 (4), 407-414, 2006 | 283 | 2006 |
Cardiac voltage-gated sodium channel Nav1. 5 is regulated by Nedd4-2 mediated ubiquitination MX van Bemmelen, JS Rougier, B Gavillet, F Apothéloz, D Daidié, ... Circulation research 95 (3), 284-291, 2004 | 253 | 2004 |
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6) C Templin, JR Ghadri, JS Rougier, A Baumer, V Kaplan, M Albesa, ... European heart journal 32 (9), 1077-1088, 2011 | 249 | 2011 |
Brugada syndrome and fever: Genetic and molecular characterization of patients carrying SCN5A mutations DI Keller, JS Rougier, JP Kucera, N Benammar, V Fressart, P Guicheney, ... Cardiovascular research 67 (3), 510-519, 2005 | 242 | 2005 |
Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins JS Rougier, MX van Bemmelen, MC Bruce, T Jespersen, B Gavillet, ... American Journal of Physiology-Cell Physiology 288 (3), C692-C701, 2005 | 162 | 2005 |
Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death H Abriel, JS Rougier, J Jalife Circulation research 116 (12), 1971-1988, 2015 | 135 | 2015 |
Sudden Cardiac Death Compendium H Abriel, JS Rougier, J Jalife Circulation Research, 2015 | 135* | 2015 |
Pdz-domain-binding motif regulates cardiomyocyte compartment-specific nav1. 5 channel expression and function D Shy, L Gillet, J Ogrodnik, M Albesa, AO Verkerk, R Wolswinkel, ... Circulation, CIRCULATIONAHA. 113.007852, 2014 | 115 | 2014 |
TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology H Abriel, N Syam, V Sottas, MY Amarouch, JS Rougier Biochemical pharmacology 84 (7), 873-881, 2012 | 95 | 2012 |
Variable Nav1. 5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a+/− mouse model AL Leoni, B Gavillet, JS Rougier, C Marionneau, V Probst, ... PloS one 5 (2), e9298, 2010 | 91 | 2010 |
Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized CaV1. 2 calcium channels JS Rougier, M Albesa, H Abriel, P Viard Journal of biological chemistry 286 (11), 8829-8838, 2011 | 75 | 2011 |
Aldosterone increases voltage-gated sodium current in ventricular myocytes C Boixel, B Gavillet, JS Rougier, H Abriel American Journal of Physiology-Heart and Circulatory Physiology 290 (6 …, 2006 | 65 | 2006 |
Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice M Albesa, J Ogrodnik, JS Rougier, H Abriel Cardiovascular research 89 (2), 320-328, 2011 | 55 | 2011 |
Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1. 5 Channel in Cardiac MyocytesNovelty and Significance CA Eichel, A Beuriot, MYE Chevalier, JS Rougier, F Louault, G Dilanian, ... Circulation research 119 (4), 544-556, 2016 | 53 | 2016 |
Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV 1.5 Channel in Cardiac MyocytesNovelty and Significance FL Rougier, G Dilanian, J Amour, A Coulombe, H Abriel, SN Hatem | 53* | |
Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients H Fodstad, S Bendahhou, JS Rougier, PJ Laitinen‐Forsblom, J Barhanin, ... Annals of medicine 38 (4), 294-304, 2006 | 51 | 2006 |
Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells L Tamo, Y Hibaoui, S Kallol, MP Alves, C Albrecht, KE Hostettler, A Feki, ... American Journal of Physiology-Lung Cellular and Molecular Physiology, 2018 | 50 | 2018 |
Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current L Gillet, JS Rougier, D Shy, S Sonntag, N Mougenot, M Essers, ... Heart Rhythm 12 (1), 181-192, 2015 | 50 | 2015 |
Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current L Gillet, JS Rougier, S Sonntag, D Shy, N Mougenot, M Essers, ... Circulation 130 (Suppl 2), A18492-A18492, 2014 | 50 | 2014 |