关注
Chris Denning
Chris Denning
Professor of Stem Cell Biology, University of Nottingham
在 nottingham.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Nature biotechnology 29 (12), 1132-1144, 2011
5972011
Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
E Matsa, D Rajamohan, E Dick, L Young, I Mellor, A Staniforth, C Denning
European heart journal 32 (8), 952-962, 2011
4702011
Small molecule absorption by PDMS in the context of drug response bioassays
BJ Van Meer, H de Vries, KSA Firth, J van Weerd, LGJ Tertoolen, ...
Biochemical and biophysical research communications 482 (2), 323-328, 2017
4082017
Deletion of the α (1, 3) galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep
C Denning, S Burl, A Ainslie, J Bracken, A Dinnyes, J Fletcher, T King, ...
Nature biotechnology 19 (6), 559-562, 2001
3782001
Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability
PW Burridge, D Anderson, H Priddle, MD Barbadillo Muñoz, ...
Stem Cells 25 (4), 929-938, 2007
3722007
Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016
3352016
MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ...
Circulation research 122 (3), e5-e16, 2018
2852018
Transgenic enrichment of cardiomyocytes from human embryonic stem cells
D Anderson, T Self, IR Mellor, G Goh, SJ Hill, C Denning
Molecular Therapy 15 (11), 2027-2036, 2007
2782007
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for …
D Mosqueira, I Mannhardt, JR Bhagwan, K Lis-Slimak, P Katili, E Scott, ...
European heart journal 39 (43), 3879-3892, 2018
2162018
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome
C Allegrucci, YZ Wu, A Thurston, CN Denning, H Priddle, CL Mummery, ...
Human molecular genetics 16 (10), 1253-1268, 2007
2042007
Automated, scalable culture of human embryonic stem cells in feeder‐free conditions
RJ Thomas, D Anderson, A Chandra, NM Smith, LE Young, D Williams, ...
Biotechnology and Bioengineering 102 (6), 1636-1644, 2009
1812009
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
A Abakir, TC Giles, A Cristini, JM Foster, N Dai, M Starczak, ...
Nature genetics 52 (1), 48-55, 2020
1782020
Materials for stem cell factories of the future
AD Celiz, JGW Smith, R Langer, DG Anderson, DA Winkler, DA Barrett, ...
Nature materials 13 (6), 570-579, 2014
1782014
Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes
E Matsa, JE Dixon, C Medway, O Georgiou, MJ Patel, K Morgan, PJ Kemp, ...
European heart journal 35 (16), 1078-1087, 2014
1462014
Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will …
C Denning, JD Pitts
Human gene therapy 8 (15), 1825-1835, 1997
1401997
Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease
C Hall, K Gehmlich, C Denning, D Pavlovic
Journal of the American Heart Association 10 (5), e019338, 2021
1302021
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy
B Lin, Y Li, L Han, AD Kaplan, Y Ao, S Kalra, GCL Bett, RL Rasmusson, ...
Disease models & mechanisms 8 (5), 457-466, 2015
1282015
Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening
E Dick, D Rajamohan, J Ronksley, C Denning
Biochemical Society Transactions 38 (4), 1037-1045, 2010
1272010
Improved genetic manipulation of human embryonic stem cells
SR Braam, C Denning, S Van Den Brink, P Kats, R Hochstenbach, ...
Nature methods 5 (5), 389-392, 2008
1262008
Current status of drug screening and disease modelling in human pluripotent stem cells
D Rajamohan, E Matsa, S Kalra, J Crutchley, A Patel, V George, ...
Bioessays 35 (3), 281-298, 2013
1252013
系统目前无法执行此操作,请稍后再试。
文章 1–20