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Chad Steven Hewitt
Chad Steven Hewitt
在 purdue.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae
CS Hewitt, NS Abutaleb, AEM Elhassanny, A Nocentini, X Cao, DP Amos, ...
ACS infectious diseases 7 (7), 1969-1984, 2021
662021
Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae
NS Abutaleb, AEM Elhassanny, A Nocentini, CS Hewitt, A Elkashif, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 51-61, 2022
392022
Ubiquitin C‐Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine‐Based Inhibitor
AD Krabill, H Chen, S Hussain, C Feng, A Abdullah, C Das, UK Aryal, ...
ChemBioChem 21 (5), 712-722, 2020
352020
Coumarins effectively inhibit bacterial α-carbonic anhydrases
S Giovannuzzi, CS Hewitt, A Nocentini, C Capasso, DP Flaherty, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 333-338, 2022
332022
Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases
W An, KJ Holly, A Nocentini, RD Imhoff, CS Hewitt, NS Abutaleb, X Cao, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1838-1844, 2022
282022
Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae
A Nocentini, CS Hewitt, MD Mastrolorenzo, DP Flaherty, CT Supuran
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1061-1066, 2021
262021
Inhibition studies of bacterial α-carbonic anhydrases with phenols
S Giovannuzzi, CS Hewitt, A Nocentini, C Capasso, G Costantino, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 666-671, 2022
242022
Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae
S Giovannuzzi, NS Abutaleb, CS Hewitt, F Carta, A Nocentini, MN Seleem, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1-8, 2022
232022
Development of ubiquitin variants with selectivity for ubiquitin C-terminal hydrolase deubiquitinases
CS Hewitt, AD Krabill, C Das, DP Flaherty
Biochemistry 59 (37), 3447-3462, 2020
152020
Optimization and Anti-Cancer Properties of Fluoromethylketones as covalent inhibitors for Ubiquitin C-terminal Hydrolase L1
AD Krabill, H Chen, S Hussain, CS Hewitt, RD Imhoff, CS Muli, C Das, ...
Molecules 26 (5), 1227, 2021
82021
Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3
CS Hewitt, C Das, DP Flaherty
Biomolecules 12 (1), 62, 2022
72022
Insights into ubiquitin product release in hydrolysis catalyzed by the bacterial deubiquitinase SdeA
MJ Sheedlo, S Kenny, IS Podkorytov, K Brown, J Ma, S Iyer, CS Hewitt, ...
Biochemistry 60 (8), 584-596, 2021
42021
Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant
S Kenny, CH Lai, TS Chiang, K Brown, CS Hewitt, AD Krabill, HT Chang, ...
Journal of Molecular Biology 436 (4), 168438, 2024
2024
Development of Ubiquitin Variants with Selectivity for the Ubiquitin C-Terminal Hydrolase Subfamily of Deubiquitinases
CS Hewitt
Purdue University, 2021
2021
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