Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition J Irving, E Matheson, L Minto, H Blair, M Case, C Halsey, I Swidenbank, ... Blood, The Journal of the American Society of Hematology 124 (23), 3420-3430, 2014 | 272 | 2014 |
Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy CC Garcia, HJ Blair, M Seager, A Coulthard, S Tennant, M Buddles, ... Journal of medical genetics 41 (3), 183-186, 2004 | 262 | 2004 |
Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia VL Ruiz-Perez, HJ Blair, ME Rodriguez-Andres, MJ Blanco, A Wilson, ... Oxford University Press for The Company of Biologists Limited 134 (16), 2903 …, 2007 | 215 | 2007 |
Subtype-specific regulatory network rewiring in acute myeloid leukemia SA Assi, MR Imperato, DJL Coleman, A Pickin, S Potluri, A Ptasinska, ... Nature genetics 51 (1), 151-162, 2019 | 182 | 2019 |
Targeting polymerised liposome vaccine carriers to intestinal M cells MA Clark, H Blair, L Liang, RN Brey, D Brayden, BH Hirst Vaccine 20 (1-2), 208-217, 2001 | 177 | 2001 |
Sequencing EVC and EVC2 identifies mutations in two-thirds of Ellis–van Creveld syndrome patients SWJ Tompson, VL Ruiz-Perez, HJ Blair, S Barton, V Navarro, JL Robson, ... Human genetics 120, 663-670, 2007 | 147 | 2007 |
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma RA Noble, N Bell, H Blair, A Sikka, H Thomas, N Phillips, S Nakjang, ... Haematologica 102 (7), 1247, 2017 | 134 | 2017 |
Towards high resolution maps of the mouse and human genomes—a facility for ordering markers to 0.1 cM resolution M Breen, L Deakln, B Macdonald, S Miller, R Sibson, E Tarttelln, P Avner, ... Human Molecular Genetics 3 (4), 621-627, 1994 | 131 | 1994 |
The oncogenic transcription factor RUNX1/ETO corrupts cell cycle regulation to drive leukemic transformation N Martinez-Soria, L McKenzie, J Draper, A Ptasinska, H Issa, S Potluri, ... Cancer Cell 34 (4), 626-642. e8, 2018 | 105 | 2018 |
Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus HJ Blair, S Tompson, YN Liu, J Campbell, K MacArthur, CP Ponting, ... BMC biology 9, 1-13, 2011 | 94 | 2011 |
The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts MTS Williams, YM Yousafzai, A Elder, K Rehe, S Bomken, ... Blood, The Journal of the American Society of Hematology 127 (16), 1998-2006, 2016 | 80 | 2016 |
Differential expression of miR-17∼ 92 identifies BCL2 as a therapeutic target in BCR-ABL-positive B-lineage acute lymphoblastic leukemia M Scherr, A Elder, K Battmer, D Barzan, S Bomken, M Ricke-Hoch, ... Leukemia 28 (3), 554-565, 2014 | 69 | 2014 |
Long-term in vitro maintenance of clonal abundance and leukaemia-initiating potential in acute lymphoblastic leukaemia D Pal, HJ Blair, A Elder, K Dormon, KJ Rennie, DJL Coleman, J Weiland, ... Leukemia 30 (8), 1691-1700, 2016 | 64 | 2016 |
Evc Regulates a Symmetrical Response to Shh Signaling in Molar Development M Nakatomi, M Hovorakova, A Gritli-Linde, HJ Blair, K MacArthur, ... Journal of dental research 92 (3), 222-228, 2013 | 62 | 2013 |
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ... Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022 | 50 | 2022 |
Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM EC Matheson, H Thomas, M Case, H Blair, RK Jackson, D Masic, G Veal, ... haematologica 104 (9), 1804, 2019 | 50 | 2019 |
Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase SE Fordham, HJ Blair, CJ Elstob, R Plummer, Y Drew, NJ Curtin, ... Blood advances 2 (10), 1157-1169, 2018 | 50 | 2018 |
Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression S Bomken, L Buechler, K Rehe, F Ponthan, A Elder, H Blair, CM Bacon, ... Leukemia 27 (3), 718-721, 2013 | 50 | 2013 |
New insights into the man-mouse comparative map of the X chromosome HJ Blair, V Reed, SH Laval, Y Boyd Genomics 19 (2), 215-220, 1994 | 50 | 1994 |
Development of a Preclinical Orthotopic Xenograft Model of Ewing Sarcoma and Other Human Malignant Bone Disease Using Advanced In Vivo Imaging B Vormoor, HK Knizia, MA Batey, GS Almeida, I Wilson, P Dildey, ... PloS one 9 (1), e85128, 2014 | 46 | 2014 |