A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity S Khan, X Zhang, D Lv, Q Zhang, Y He, P Zhang, X Liu, D Thummuri, ... Nature medicine 25 (12), 1938-1947, 2019 | 424 | 2019 |
Dried blood spots: concepts, present status, and future perspectives in bioanalysis A Sharma, S Jaiswal, M Shukla, J Lal Drug testing and analysis 6 (5), 399-414, 2014 | 185 | 2014 |
Discovery of a new class of natural product-inspired quinazolinone hybrid as potent antileishmanial agents M Sharma, K Chauhan, R Shivahare, P Vishwakarma, MK Suthar, ... Journal of Medicinal Chemistry 56 (11), 4374-4392, 2013 | 148 | 2013 |
Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom … S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ... Journal of medicinal chemistry 63 (1), 433-439, 2019 | 113 | 2019 |
Suspected adulteration of commercial kratom products with 7-hydroxymitragynine AG Lydecker, A Sharma, CR McCurdy, BA Avery, KM Babu, EW Boyer Journal of Medical Toxicology 12, 341-349, 2016 | 112 | 2016 |
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom) SH Kamble, A Sharma, TI King, F León, CR McCurdy, BA Avery Xenobiotica, 2019 | 94 | 2019 |
Synthesis and bioevaluation of novel 4-aminoquinoline-tetrazole derivatives as potent antimalarial agents S Pandey, P Agarwal, K Srivastava, S RajaKumar, SK Puri, P Verma, ... European journal of medicinal chemistry 66, 69-81, 2013 | 92 | 2013 |
Patterns and reasons for kratom (Mitragyna speciosa) use among current and former opioid poly-drug users D Singh, NJY Chear, S Narayanan, F Leon, A Sharma, CR McCurdy, ... Journal of ethnopharmacology 249, 112462, 2020 | 80 | 2020 |
Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography … A Sharma, SH Kamble, F León, NJY Chear, TI King, EC Berthold, ... Drug testing and analysis 11 (8), 1162-1171, 2019 | 80 | 2019 |
A combination of complexation and self-nanoemulsifying drug delivery system for enhancing oral bioavailability and anticancer efficacy of curcumin M Shukla, S Jaiswal, A Sharma, PK Srivastava, A Arya, AK Dwivedi, J Lal Drug development and industrial pharmacy 43 (5), 847-861, 2017 | 80 | 2017 |
Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin VK Pawar, Y Singh, K Sharma, A Shrivastav, A Sharma, A Singh, ... International journal of biological macromolecules 122, 1100-1114, 2019 | 66 | 2019 |
Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis S Singh, KK Roy, SR Khan, VK Kashyap, A Sharma, S Jaiswal, ... Bioorganic & Medicinal Chemistry 23 (4), 742-752, 2015 | 62 | 2015 |
Role of enterohepatic recirculation in drug disposition: cooperation and complications MY Malik, S Jaiswal, A Sharma, M Shukla, J Lal Drug metabolism reviews 48 (2), 281-327, 2016 | 57 | 2016 |
Lyophilized kratom tea as a therapeutic option for opioid dependence LL Wilson, HM Harris, SO Eans, AC Brice-Tutt, TJ Cirino, HM Stacy, ... Drug and Alcohol Dependence 216, 108310, 2020 | 56 | 2020 |
Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors NJY Chear, F León, A Sharma, SRR Kanumuri, G Zwolinski, KA Abboud, ... Journal of natural products 84 (4), 1034-1043, 2021 | 55 | 2021 |
Ameliorative potential of ferulic acid in vincristine-induced painful neuropathy in rats: an evidence of behavioral and biochemical examination B Vashistha, A Sharma, V Jain Nutritional Neuroscience 20 (1), 60-70, 2017 | 53 | 2017 |
Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids SH Kamble, A Sharma, TI King, EC Berthold, F León, PKL Meyer, ... Toxicology letters 319, 148-154, 2020 | 50 | 2020 |
Metabolism of a kratom alkaloid metabolite in human plasma increases its opioid potency and efficacy SH Kamble, F León, TI King, EC Berthold, C Lopera-Londoño, ... ACS pharmacology & translational science 3 (6), 1063-1068, 2020 | 48 | 2020 |
Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors F León, S Obeng, M Mottinelli, Y Chen, TI King, EC Berthold, SH Kamble, ... Journal of medicinal chemistry 64 (18), 13510-13523, 2021 | 47 | 2021 |
Comparative pharmacokinetics of mitragynine after oral administration of Mitragyna speciosa (Kratom) leaf extracts in rats BA Avery, SP Boddu, A Sharma, EB Furr, F Leon, SJ Cutler, CR McCurdy Planta medica 85 (04), 340-346, 2019 | 47 | 2019 |