Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis H Khalil, O Kanisicak, V Prasad, RN Correll, X Fu, T Schips, RJ Vagnozzi, ... The Journal of clinical investigation 127 (10), 3770-3783, 2017 | 738 | 2017 |
c-kit+ cells minimally contribute cardiomyocytes to the heart JH Van Berlo, O Kanisicak, M Maillet, RJ Vagnozzi, J Karch, SCJ Lin, ... Nature 509 (7500), 337-341, 2014 | 615 | 2014 |
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart X Fu, H Khalil, O Kanisicak, JG Boyer, RJ Vagnozzi, BD Maliken, ... The Journal of clinical investigation 128 (5), 2127-2143, 2018 | 529 | 2018 |
An acute immune response underlies the benefit of cardiac stem cell therapy RJ Vagnozzi, M Maillet, MA Sargent, H Khalil, AKZ Johansen, ... Nature 577 (7790), 405-409, 2020 | 470 | 2020 |
Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice JW Elrod, R Wong, S Mishra, RJ Vagnozzi, B Sakthievel, ... The Journal of clinical investigation 120 (10), 3680-3687, 2010 | 434 | 2010 |
The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart JQ Kwong, X Lu, RN Correll, JA Schwanekamp, RJ Vagnozzi, MA Sargent, ... Cell reports 12 (1), 15-22, 2015 | 352 | 2015 |
Yolk sac macrophage progenitors traffic to the embryo during defined stages of development C Stremmel, R Schuchert, F Wagner, R Thaler, T Weinberger, R Pick, ... Nature communications 9 (1), 75, 2018 | 258 | 2018 |
Sunitinib‐induced cardiotoxicity is mediated by off‐target inhibition of AMP‐activated protein kinase R Kerkela, KC Woulfe, JB Durand, R Vagnozzi, D Kramer, TF Chu, ... Clinical and translational science 2 (1), 15-25, 2009 | 258 | 2009 |
Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart H Lal, F Ahmad, J Zhou, JE Yu, RJ Vagnozzi, Y Guo, D Yu, EJ Tsai, ... Circulation 130 (5), 419-430, 2014 | 175 | 2014 |
GSK-3α is a central regulator of age-related pathologies in mice J Zhou, TA Freeman, F Ahmad, X Shang, E Mangano, E Gao, J Farber, ... The Journal of clinical investigation 123 (4), 1821-1832, 2013 | 169 | 2013 |
MICU1 motifs define mitochondrial calcium uniporter binding and activity NE Hoffman, HC Chandramoorthy, S Shamugapriya, X Zhang, S Rajan, ... Cell reports 5 (6), 1576-1588, 2013 | 150 | 2013 |
Glycogen synthase kinase-3β regulates post–myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo KC Woulfe, E Gao, H Lal, D Harris, Q Fan, R Vagnozzi, M DeCaul, ... Circulation research 106 (10), 1635-1645, 2010 | 134 | 2010 |
Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart RJ Vagnozzi, MA Sargent, SCJ Lin, NJ Palpant, CE Murry, JD Molkentin Circulation 138 (25), 2931-2939, 2018 | 94 | 2018 |
Acute catecholamine exposure causes reversible myocyte injury without cardiac regeneration M Wallner, JM Duran, S Mohsin, CD Troupes, D Vanhoutte, G Borghetti, ... Circulation research 119 (7), 865-879, 2016 | 88 | 2016 |
Sorafenib cardiotoxicity increases mortality after myocardial infarction JM Duran, CA Makarewich, D Trappanese, P Gross, S Husain, J Dunn, ... Circulation research 114 (11), 1700-1712, 2014 | 87 | 2014 |
Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart H Khalil, O Kanisicak, RJ Vagnozzi, AK Johansen, BD Maliken, V Prasad, ... JCI insight 4 (15), 2019 | 75 | 2019 |
Glycogen Synthase Kinase-3α Limits Ischemic Injury, Cardiac Rupture, Post–Myocardial Infarction Remodeling and Death H Lal, J Zhou, F Ahmad, R Zaka, RJ Vagnozzi, M DeCaul, J Woodgett, ... Circulation 125 (1), 65-75, 2012 | 75 | 2012 |
Cardiomyocyte-Specific Deletion of Gsk3α Mitigates Post–Myocardial Infarction Remodeling, Contractile Dysfunction, and Heart Failure F Ahmad, H Lal, J Zhou, RJ Vagnozzi, JE Yu, X Shang, JR Woodgett, ... Journal of the American College of Cardiology 64 (7), 696-706, 2014 | 74 | 2014 |
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart RJ Vagnozzi, GJ Gatto Jr, LS Kallander, NE Hoffman, K Mallilankaraman, ... Science translational medicine 5 (207), 207ra141-207ra141, 2013 | 74 | 2013 |
Deletion of periostin protects against atherosclerosis in mice by altering inflammation and extracellular matrix remodeling JA Schwanekamp, A Lorts, RJ Vagnozzi, D Vanhoutte, JD Molkentin Arteriosclerosis, thrombosis, and vascular biology 36 (1), 60-68, 2016 | 73 | 2016 |