Resolving postoperative neuroinflammation and cognitive decline N Terrando, LI Eriksson, J Kyu Ryu, T Yang, C Monaco, M Feldmann, ... Annals of neurology 70 (6), 986-995, 2011 | 647 | 2011 |
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation D Davalos, J Kyu Ryu, M Merlini, KM Baeten, N Le Moan, MA Petersen, ... Nature communications 3 (1), 1227, 2012 | 588 | 2012 |
A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain JK Ryu, JG McLarnon Journal of cellular and molecular medicine 13 (9a), 2911-2925, 2009 | 454 | 2009 |
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-β after vascular damage C Schachtrup, JK Ryu, MJ Helmrick, E Vagena, DK Galanakis, JL Degen, ... Journal of Neuroscience 30 (17), 5843-5854, 2010 | 423 | 2010 |
Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics MA Petersen, JK Ryu, K Akassoglou Nature Reviews Neuroscience 19 (5), 283-301, 2018 | 380 | 2018 |
Fibrinogen induces microglia-mediated spine elimination and cognitive impairment in an Alzheimer’s disease model M Merlini, VA Rafalski, PER Coronado, TM Gill, M Ellisman, ... Neuron 101 (6), 1099-1108. e6, 2019 | 314 | 2019 |
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism T Xu, KM Stewart, X Wang, K Liu, M Xie, JK Ryu, K Li, T Ma, H Wang, L Ni, ... Nature 548 (7666), 228-233, 2017 | 309 | 2017 |
Upregulated Expression of Purinergic P2X7 Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus JG McLarnon, JK Ryu, DG Walker, HB Choi Journal of Neuropathology & Experimental Neurology 65 (11), 1090-1097, 2006 | 295 | 2006 |
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation JK Ryu, MA Petersen, SG Murray, KM Baeten, A Meyer-Franke, JP Chan, ... Nature communications 6 (1), 8164, 2015 | 272 | 2015 |
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase HB Choi, GRJ Gordon, N Zhou, C Tai, RL Rungta, J Martinez, TA Milner, ... Neuron 75 (6), 1094-1104, 2012 | 272 | 2012 |
Fractalkine and fractalkine receptors in human neurons and glial cells K Hatori, A Nagai, R Heisel, JK Ryu, SU Kim Journal of neuroscience research 69 (3), 418-426, 2002 | 266 | 2002 |
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease JK Ryu, J Kim, SJ Cho, K Hatori, A Nagai, HB Choi, MC Lee, ... Neurobiology of disease 16 (1), 68-77, 2004 | 220 | 2004 |
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain HB Choi, JK Ryu, SU Kim, JG McLarnon Journal of Neuroscience 27 (18), 4957-4968, 2007 | 213 | 2007 |
Fibrinogen activates BMP signaling in oligodendrocyte progenitor cells and inhibits remyelination after vascular damage MA Petersen, JK Ryu, KJ Chang, A Etxeberria, S Bardehle, AS Mendiola, ... Neuron 96 (5), 1003-1012. e7, 2017 | 179 | 2017 |
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration JK Ryu, VA Rafalski, A Meyer-Franke, RA Adams, SB Poda, ... Nature immunology 19 (11), 1212-1223, 2018 | 171 | 2018 |
SIRT1 deacetylates RORγt and enhances Th17 cell generation HW Lim, SG Kang, JK Ryu, B Schilling, M Fei, IS Lee, A Kehasse, ... Journal of Experimental Medicine 212 (5), 607-617, 2015 | 169 | 2015 |
Minocycline inhibits neuronal death and glial activation induced by β‐amyloid peptide in rat hippocampus JK Ryu, S Franciosi, P Sattayaprasert, SU Kim, JG McLarnon Glia 48 (1), 85-90, 2004 | 167 | 2004 |
Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease JK Ryu, JG McLarnon Neuroreport 19 (17), 1715-1719, 2008 | 153 | 2008 |
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation AS Mendiola, JK Ryu, S Bardehle, A Meyer-Franke, KKH Ang, C Wilson, ... Nature immunology 21 (5), 513-524, 2020 | 152 | 2020 |
Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease S Franciosi, JK Ryu, Y Shim, A Hill, C Connolly, MR Hayden, ... Neurobiology of disease 45 (1), 438-449, 2012 | 134 | 2012 |