Platelet signaling: a complex interplay between inhibitory and activatory networks AP Bye, AJ Unsworth, JM Gibbins Journal of Thrombosis and Haemostasis 14 (5), 918-930, 2016 | 192 | 2016 |
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib AP Bye, AJ Unsworth, MJ Desborough, CAT Hildyard, N Appleby, D Bruce, ... Blood advances 1 (26), 2610-2623, 2017 | 126 | 2017 |
Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen AP Bye, AJ Unsworth, S Vaiyapuri, AR Stainer, MJ Fry, JM Gibbins Arteriosclerosis, thrombosis, and vascular biology 35 (11), 2326-2335, 2015 | 107 | 2015 |
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis S Vaiyapuri, CI Jones, P Sasikumar, LA Moraes, SJ Munger, JR Wright, ... Circulation 125 (20), 2479-2491, 2012 | 95 | 2012 |
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets AP Bye, W Hoepel, JL Mitchell, S Jégouic, S Loureiro, T Sage, ... Blood, The Journal of the American Society of Hematology 138 (16), 1481-1489, 2021 | 83 | 2021 |
The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects AR Stainer, P Sasikumar, AP Bye, AJ Unsworth, LM Holbrook, M Tindall, ... Th Open 3 (03), e244-e258, 2019 | 55 | 2019 |
RXR ligands negatively regulate thrombosis and hemostasis AJ Unsworth, GD Flora, P Sasikumar, AP Bye, T Sage, N Kriek, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 812-822, 2017 | 37 | 2017 |
Farnesoid X receptor and its ligands inhibit the function of platelets LA Moraes, AJ Unsworth, S Vaiyapuri, MS Ali, P Sasikumar, T Sage, ... Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2324-2333, 2016 | 33 | 2016 |
PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity AJ Unsworth, N Kriek, AP Bye, K Naran, T Sage, GD Flora, JM Gibbins Journal of Thrombosis and Haemostasis 15 (2), 356-369, 2017 | 30 | 2017 |
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis P Sasikumar, KS AlOuda, WJ Kaiser, LM Holbrook, N Kriek, AJ Unsworth, ... Journal of Thrombosis and Haemostasis 16 (5), 946-959, 2018 | 26 | 2018 |
Multiparameter phenotyping of platelet reactivity for stratification of human cohorts JL Dunster, AP Bye, N Kriek, T Sage, JL Mitchell, C Kempster, J Batista, ... Blood advances 5 (20), 4017-4030, 2021 | 20 | 2021 |
Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets AJ Unsworth, AP Bye, DS Tannetta, MJR Desborough, N Kriek, T Sage, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1482-1493, 2017 | 20 | 2017 |
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation JL Dunster, AJ Unsworth, AP Bye, EJ Haining, MA Sowa, Y Di, T Sage, ... Journal of Thrombosis and Haemostasis 18 (2), 485-496, 2020 | 19 | 2020 |
Ca2+ waves coordinate purinergic receptor–evoked integrin activation and polarization AP Bye, JM Gibbins, MP Mahaut-Smith Science Signaling 13 (615), eaav7354, 2020 | 14 | 2020 |
1, 8-Cineole affects agonists-induced platelet activation, thrombus formation and haemostasis KA Alatawi, D Ravishankar, PH Patra, AP Bye, AR Stainer, K Patel, ... Cells 10 (10), 2616, 2021 | 13 | 2021 |
Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling AJ Unsworth, AP Bye, T Sage, RS Gaspar, N Eaton, C Drew, A Stainer, ... Haematologica 106 (7), 1968, 2021 | 11 | 2021 |
Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets KA Sahli, GD Flora, P Sasikumar, AH Maghrabi, LM Holbrook, SK AlOuda, ... Blood, The Journal of the American Society of Hematology 137 (6), 830-843, 2021 | 11 | 2021 |
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring RS Gaspar, AJ Unsworth, A Al-Dibouni, AP Bye, T Sage, M Stewart, ... Scientific reports 11 (1), 1473, 2021 | 10 | 2021 |
Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction AJ Unsworth, AP Bye, N Kriek, T Sage, AA Osborne, D Donaghy, ... Platelets 30 (6), 762-772, 2019 | 9 | 2019 |
Screening and high-throughput platelet assays AP Bye, AJ Unsworth, JM Gibbins Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives …, 2018 | 8 | 2018 |