Telomere dysfunction induces metabolic and mitochondrial compromise E Sahin, S Colla, M Liesa, J Moslehi, FL Müller, M Guo, M Cooper, ... Nature 470 (7334), 359-365, 2011 | 1394 | 2011 |
Regeneration and orthotopic transplantation of a bioartificial lung HC Ott, B Clippinger, C Conrad, C Schuetz, I Pomerantseva, L Ikonomou, ... Nature medicine 16 (8), 927-933, 2010 | 1312 | 2010 |
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette CA Sommer, M Stadtfeld, GJ Murphy, K Hochedlinger, DN Kotton, ... Stem cells 27 (3), 543-549, 2009 | 871 | 2009 |
Bone marrow-derived cells as progenitors of lung alveolar epithelium DN Kotton, BY Ma, WV Cardoso, EA Sanderson, RS Summer, ... Oxford University Press for The Company of Biologists Limited 128 (24), 5181 …, 2001 | 810 | 2001 |
Lung regeneration: mechanisms, applications and emerging stem cell populations DN Kotton, EE Morrisey Nature medicine 20 (8), 822-832, 2014 | 530 | 2014 |
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette A Somers, JC Jean, CA Sommer, A Omari, CC Ford, JA Mills, L Ying, ... Stem cells 28 (10), 1728-1740, 2010 | 493 | 2010 |
Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells A Jacob, M Morley, F Hawkins, KB McCauley, JC Jean, H Heins, CL Na, ... Cell stem cell 21 (4), 472-488. e10, 2017 | 468 | 2017 |
Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells TA Longmire, L Ikonomou, F Hawkins, C Christodoulou, Y Cao, JC Jean, ... Cell stem cell 10 (4), 398-411, 2012 | 457 | 2012 |
Efficient derivation of functional human airway epithelium from pluripotent stem cells via temporal regulation of Wnt signaling KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton Cell stem cell 20 (6), 844-857. e6, 2017 | 382 | 2017 |
Side population cells and Bcrp1 expression in lung R Summer, DN Kotton, X Sun, B Ma, K Fitzsimmons, A Fine American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (1 …, 2003 | 354 | 2003 |
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector CA Sommer, AG Sommer, TA Longmire, C Christodoulou, DD Thomas, ... Stem cells 28 (1), 64-74, 2010 | 348 | 2010 |
Failure of bone marrow to reconstitute lung epithelium DN Kotton, AJ Fabian, RC Mulligan American journal of respiratory cell and molecular biology 33 (4), 328-334, 2005 | 336 | 2005 |
SARS-CoV-2 infection of pluripotent stem cell-derived human lung alveolar type 2 cells elicits a rapid epithelial-intrinsic inflammatory response J Huang, AJ Hume, KM Abo, RB Werder, C Villacorta-Martin, ... Cell Stem Cell 27 (6), 962-973. e7, 2020 | 329 | 2020 |
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells X Cheng, L Ying, L Lu, AM Galvão, JA Mills, HC Lin, DN Kotton, SS Shen, ... Cell stem cell 10 (4), 371-384, 2012 | 300 | 2012 |
The cellular and physiological basis for lung repair and regeneration: past, present, and future MC Basil, J Katzen, AE Engler, M Guo, MJ Herriges, JJ Kathiriya, ... Cell stem cell 26 (4), 482-502, 2020 | 286 | 2020 |
The prolonged life-span of alveolar macrophages J Murphy, R Summer, AA Wilson, DN Kotton, A Fine American journal of respiratory cell and molecular biology 38 (4), 380-385, 2008 | 250 | 2008 |
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics C Terrenoire, K Wang, KW Chan Tung, WK Chung, RH Pass, JT Lu, ... Journal of General Physiology 141 (1), 61-72, 2013 | 226 | 2013 |
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes Y Li, DM Renner, CE Comar, JN Whelan, HM Reyes, FL Cardenas-Diaz, ... Proceedings of the National Academy of Sciences 118 (16), e2022643118, 2021 | 222 | 2021 |
miR-129 regulates cell proliferation by downregulating Cdk6 expression J Wu, J Qian, C Li, L Kwok, F Cheng, P Liu, C Perdomo, D Kotton, C Vaziri, ... Cell cycle 9 (9), 1809-1818, 2010 | 220 | 2010 |
Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells AM Crane, P Kramer, JH Bui, WJ Chung, XS Li, ML Gonzalez-Garay, ... Stem cell reports 4 (4), 569-577, 2015 | 207 | 2015 |