JAK–STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response M Kleppe, M Kwak, P Koppikar, M Riester, M Keller, L Bastian, T Hricik, ... Cancer discovery 5 (3), 316-331, 2015 | 308* | 2015 |
High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity Y Lu, JJ Chen, L Mu, Q Xue, Y Wu, PH Wu, J Li, AO Vortmeyer, ... Analytical Chemistry, 2013 | 183 | 2013 |
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration H Jayatilaka, P Tyle, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee, PH Wu, ... Nature communications 8 (1), 15584, 2017 | 172 | 2017 |
Biophysical and biomolecular determination of cellular age in humans JM Phillip, PH Wu, DM Gilkes, W Williams, S McGovern, J Daya, J Chen, ... Nature biomedical engineering 1 (7), 0093, 2017 | 92 | 2017 |
System, device and method for high-throughput multi-plexed detection R Fan, Y Lu, J Chen US Patent 9188586 B2, 2015 | 89 | 2015 |
Interfacing inorganic nanowire arrays and living cells for cellular function analysis M Kwak, L Han, JJ Chen, R Fan small 11 (42), 5600-5610, 2015 | 65 | 2015 |
A microchip platform for interrogating tumor–macrophage paracrine signaling at the single-cell level M Elitas, K Brower, Y Lu, JJ Chen, R Fan Lab on a Chip 14 (18), 3582-3588, 2014 | 59 | 2014 |
Single-cell protein secretion detection and profiling Z Chen, JJ Chen, R Fan Annual Review of Analytical Chemistry 12 (1), 431-449, 2019 | 48 | 2019 |
System, device and method for high-throughput multi-plexed detection R Fan, Y Lu, J Chen US Patent 9,506,917, 2016 | 42 | 2016 |
Single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell–cell interaction M Kwak, L Mu, Y Lu, JJ Chen, K Brower, R Fan Frontiers in oncology 3, 10, 2013 | 26* | 2013 |
CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis AJ Dunbar, D Kim, M Lu, M Farina, RL Bowman, JL Yang, Y Park, ... Blood, The Journal of the American Society of Hematology 141 (20), 2508-2519, 2023 | 25 | 2023 |
Advanced cell mapping visualizations for single cell functional proteomics enabling patient stratification N Bowman, D Liu, P Paczkowski, J Chen, J Rossi, S Mackay, A Bot, ... Proteomics 20 (13), 1900270, 2020 | 15 | 2020 |
CD49d expression identifies a biologically distinct subtype of chronic lymphocytic leukemia with inferior progression-free survival on BTK inhibitor therapy A Alsadhan, J Chen, EM Gaglione, C Underbayev, PL Tuma, X Tian, ... Clinical Cancer Research 29 (18), 3612-3621, 2023 | 12 | 2023 |
System, device and method for high-throughput multi-plexed detection R Fan, Y Lu, J Chen US Patent 10,274,486, 2019 | 10 | 2019 |
Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production YA Kang, H Paik, SY Zhang, JJ Chen, OC Olson, CA Mitchell, A Collins, ... Journal of Experimental Medicine 220 (8), e20230088, 2023 | 9 | 2023 |
A model program for hepatitis B vaccination and education of schoolchildren in rural China JJ Chen, ET Chang, YR Chen, MB Bailey, SKS So International journal of public health 57, 581-588, 2012 | 9 | 2012 |
HIV vaccines induce CD8+ T cells with low antigen receptor sensitivity SA Migueles, DM Nettere, NV Gavil, LT Wang, SA Toulmin, EP Kelly, ... Science 382 (6676), 1270-1276, 2023 | 6 | 2023 |
System, device and method for high-throughput multi-plexed detection R Fan, Y Lu, J Chen US Patent 10,983,116, 2021 | 6 | 2021 |
A model HBV catch-up immunization and education project in Qinghai, China JJ Chen, M Bergin, L Zhang, Z Wang, Y Zhang, J Zhao, C Su, ET Chang, ... National Immunization Conference 2008, 2008 | 6 | 2008 |
Single-cell cytokine profiling to investigate cellular functional diversity in hematopoietic malignancies JJ Chen, M Kwak, R Fan Chronic Myeloid Leukemia: Methods and Protocols, 243-254, 2016 | 3 | 2016 |