A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice A Saha, S Hyzy, T Lamothe, K Hammond, N Clark, L Lanieri, P Bhattarai, ... Blood, The Journal of the American Society of Hematology 139 (11), 1743-1759, 2022 | 29 | 2022 |
Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-1 in Human Breast Cancer SS Timur, P Bhattarai, RN Gürsoy, İ Vural, BA Khaw Pharmaceutical research 34, 352-364, 2017 | 16 | 2017 |
Imaging doxorubicin and polymer-drug conjugates of doxorubicin-induced cardiotoxicity with bispecific anti-myosin-anti-DTPA antibody and Tc-99m-labeled polymers R Panwar, P Bhattarai, V Patil, K Gada, S Majewski, BA Khaw Journal of Nuclear Cardiology 26, 1327-1344, 2019 | 7 | 2019 |
A single dose of a novel anti-human CD117-amanitin antibody drug conjugate (ADC) engineered for a short half-life provides dual conditioning and anti-leukemic activity and … L Lanieri, TL Lamothe, O Miske, SM McDonough, GN Sarma, P Bhattarai, ... Blood 136, 47-48, 2020 | 6 | 2020 |
CD117 Antibody Drug Conjugate-Based Conditioning Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model N Uchida, U Stasula, M Hinds, P Germino-Watnick, AE Krouse, NS Linde, ... Blood 138, 560, 2021 | 4 | 2021 |
An in vitro demonstration of overcoming drug resistance in SKOV3 TR and MCF7 ADR with targeted delivery of polymer pro-drug conjugates P Bhattarai, D Vance, A Hatefi, BA Khaw Journal of drug targeting 25 (5), 436-450, 2017 | 3 | 2017 |
A novel targeted approach to achieve immune system reset: CD45-Targeted antibody drug conjugates enable autologous HSCT and ameliorate disease in preclinical autoimmune disease … GO Gillard, JL Proctor, ML Brooks, TL Lamothe, SL Hyzy, SM McDonough, ... Biology of Blood and Marrow Transplantation 26 (3), S307-S308, 2020 | 2 | 2020 |
A novel targeted approach to achieve immune system reset: CD45-targeted antibody drug conjugates enable autologous HSCT, ameliorate disease in autoimmune models, potently kill … GO Gillard, JL Proctor, ML Brooks, TL Lamothe, SL Hyzy, O Mikse, ... Blood 134, 3208, 2019 | 2 | 2019 |
Administration of a CD45 antibody drug conjugate as a novel, targeted approach to achieve immune system reset: A single dose of CD45-targeted ADC safely conditions for … GR Gillard, J Proctor, M Brooks, T Lamothe, S Hyzy, S McDonough, ... ARTHRITIS & RHEUMATOLOGY 71, 2019 | 2 | 2019 |
OP0307 A novel targeted approach to achieve immune system reset: CD45-targeted antibody drug conjugates ameliorate disease in preclinical autoimmune disease models and enable … G Gillard, J Proctor, S Hyzy, O Mikse, T Lamothe, S McDonough, N Clark, ... Annals of the Rheumatic Diseases 79 (Suppl 1), 190-191, 2020 | 1 | 2020 |
Single Agent CD117-Targeted Antibody Drug Conjugate in Combination with Lympho-Depleting Antibodies Enables Allogenic Hematopoietic Stem Cell Transplantation in Mice without … L Lanieri, TL Lamothe, P raj Bhattarai, R Palchaudhuri, LM Olson 2022 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2022 | | 2022 |
A Sngle Injection of CD117 Antibody-Drug Conjugate Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model N Uchida, U Stasula, M Hinds, P Germino-Watnick, AE Krouse, NS Linde, ... MOLECULAR THERAPY 30 (4), 385-385, 2022 | | 2022 |
CD117 Antibody Drug Conjugate-Based Conditioning Enables Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model R Palchaudhuri, N Uchida, U Stasula, M Hinds, P Germino-Watnick, ... Transplantation and Cellular Therapy 28 (3), S238, 2022 | | 2022 |
Single Agent CD117-Targeted Antibody Drug Conjugate in Combination with Lymphodepleting Antibodies Enables Allogenic Hematopoietic Stem Cell Transplantation in Mice without … L Lanieri, T Lamothe, P Bhattarai, R Palchaudhuri, L Olson Blood 138, 1682, 2021 | | 2021 |
A Single Dose of a Novel Anti-Human CD117-Amanitin Antibody Drug Conjugate (ADC) Engineered for a Short Half-Life Provides Dual Conditioning and Anti-Leukemia Activity and … L Lanieri, TL Lamothe, O Mikse, SM McDonough, GN Sarma, ... 2021 TCT| Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, 2021 | | 2021 |
A Single Dose of a Novel Anti-Human Short Half-Life Engineered CD45-Targeted Antibody-Drug Conjugate (ADC) Is Cytoreductive on Patient-Derived Tumors and Extends Survival … JL Proctor, GO Gillard, O Mikse, L Lanieri, TL Lamothe, ML Brooks, L Kien, ... Biology of Blood and Marrow Transplantation 26 (3), S96, 2020 | | 2020 |
Changes in Cardiac Isomyosin Composition in an Iron Loading Anemia Rat Model WT Cheng, NY Kim, P Bhattarai, M Han, AV Menon, J Kim, BA Khaw Journal of Cardiology and Cardiovascular Sciences 3 (4), 2019 | | 2019 |
Methods and compositions for overcoming drug-resistance in cancer by targeted delivery of pro-drug-nano-polymers B Khaw, P Bhattarai US Patent App. 15/196,968, 2016 | | 2016 |
Methods and compositions for overcoming drug-resistance in cancer by targeted delivery of pro-drug-nano-polymers B Khaw, P Bhattarai US Patent App. 15/135,543, 2016 | | 2016 |
Immuno-molecular quantitation of β-isomyosin in Belgrade rats, a model of hypertrophic cardiomyopathy. BA Khaw, WT Chang, P Bhattarai, M Han, J Kim Journal of Nuclear Medicine 57 (supplement 2), 1226-1226, 2016 | | 2016 |