Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules K Leder, K Pitter, Q LaPlant, D Hambardzumyan, BD Ross, TA Chan, ... Cell 156 (3), 603-616, 2014 | 283 | 2014 |
Intratumor heterogeneity in evolutionary models of tumor progression R Durrett, J Foo, K Leder, J Mayberry, F Michor Genetics 188 (2), 461-477, 2011 | 154 | 2011 |
A mathematical model of tumor growth and its response to single irradiation Y Watanabe, EL Dahlman, KZ Leder, SK Hui Theoretical Biology and Medical Modelling 13, 1-20, 2016 | 108 | 2016 |
The impact of microenvironmental heterogeneity on the evolution of drug resistance in cancer cells SM Mumenthaler, J Foo, NC Choi, N Heise, K Leder, DB Agus, W Pao, ... Cancer informatics 14, CIN. S19338, 2015 | 105 | 2015 |
Importance sampling for sums of random variables with regularly varying tails P Dupuis, K Leder, H Wang ACM Transactions on Modeling and Computer Simulation (TOMACS) 17 (3), 14-es, 2007 | 92 | 2007 |
Stochastic dynamics of cancer initiation J Foo, K Leder, F Michor Physical biology 8 (1), 015002, 2011 | 74 | 2011 |
Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia K Leder, J Foo, B Skaggs, M Gorre, CL Sawyers, F Michor PloS one 6 (11), e27682, 2011 | 69 | 2011 |
Evolutionary dynamics of tumor progression with random fitness values R Durrett, J Foo, K Leder, J Mayberry, F Michor Theoretical population biology 78 (1), 54-66, 2010 | 68 | 2010 |
Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer SM Mumenthaler, J Foo, K Leder, NC Choi, DB Agus, W Pao, P Mallick, ... Molecular pharmaceutics 8 (6), 2069-2079, 2011 | 65 | 2011 |
The therapeutic implications of plasticity of the cancer stem cell phenotype K Leder, EC Holland, F Michor PloS one 5 (12), e14366, 2010 | 63 | 2010 |
Understanding the role of phenotypic switching in cancer drug resistance EB Gunnarsson, S De, K Leder, J Foo Journal of theoretical biology 490, 110162, 2020 | 50 | 2020 |
Quantifying the dynamics of field cancerization in tobacco-related head and neck cancer: a multiscale modeling approach MD Ryser, WT Lee, NE Ready, KZ Leder, J Foo Cancer research 76 (24), 7078-7088, 2016 | 47 | 2016 |
Spatial Moran models, II: cancer initiation in spatially structured tissue R Durrett, J Foo, K Leder Journal of mathematical biology 72, 1369-1400, 2016 | 47* | 2016 |
Optimization of radiation dosing schedules for proneural glioblastoma H Badri, K Pitter, EC Holland, F Michor, K Leder Journal of mathematical biology 72, 1301-1336, 2016 | 47 | 2016 |
Multifocality and recurrence risk: a quantitative model of field cancerization J Foo, K Leder, MD Ryser Journal of theoretical biology 355, 170-184, 2014 | 45 | 2014 |
Efficient simulation of light-tailed sums: an old-folk song sung to a faster new tune... JH Blanchet, K Leder, PW Glynn Monte Carlo and Quasi-Monte Carlo Methods 2008, 227-248, 2009 | 36* | 2009 |
Optimal radiotherapy dose schedules under parametric uncertainty H Badri, Y Watanabe, K Leder Physics in Medicine & Biology 61 (1), 338, 2015 | 34* | 2015 |
Dynamics of cancer recurrence J Foo, K Leder | 34 | 2013 |
An evolutionary approach for identifying driver mutations in colorectal cancer J Foo, LL Liu, K Leder, M Riester, Y Iwasa, C Lengauer, F Michor PLoS computational biology 11 (9), e1004350, 2015 | 32 | 2015 |
Large deviations and importance sampling for a tandem network with slow-down P Dupuis, K Leder, H Wang Queueing Systems 57 (2), 71-83, 2007 | 31 | 2007 |