Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1083 | 2014 |
A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ... Cell metabolism 22 (1), 86-99, 2015 | 906 | 2015 |
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans J Guevara-Aguirre, P Balasubramanian, M Guevara-Aguirre, M Wei, ... Science translational medicine 3 (70), 70ra13-70ra13, 2011 | 854 | 2011 |
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression CW Cheng, GB Adams, L Perin, M Wei, X Zhou, BS Lam, S Da Sacco, ... Cell stem cell 14 (6), 810-823, 2014 | 577 | 2014 |
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease M Wei, S Brandhorst, M Shelehchi, H Mirzaei, CW Cheng, J Budniak, ... Science translational medicine 9 (377), eaai8700, 2017 | 558 | 2017 |
Fasting-mimicking diet promotes Ngn3-driven β-cell regeneration to reverse diabetes CW Cheng, V Villani, R Buono, M Wei, S Kumar, OH Yilmaz, P Cohen, ... Cell 168 (5), 775-788. e12, 2017 | 380 | 2017 |
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ... Cancer cell 30 (1), 136-146, 2016 | 364 | 2016 |
Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and aging MM Mihaylova, CW Cheng, AQ Cao, S Tripathi, MD Mana, ... Cell stem cell 22 (5), 769-778. e4, 2018 | 348 | 2018 |
Ketone body signaling mediates intestinal stem cell homeostasis and adaptation to diet CW Cheng, M Biton, AL Haber, N Gunduz, G Eng, LT Gaynor, S Tripathi, ... Cell 178 (5), 1115-1131. e15, 2019 | 271 | 2019 |
Safety and feasibility of fasting in combination with platinum-based chemotherapy TB Dorff, S Groshen, A Garcia, M Shah, D Tsao-Wei, H Pham, CW Cheng, ... BMC cancer 16, 1-9, 2016 | 221 | 2016 |
Cell size is a determinant of stem cell potential during aging J Lengefeld, CW Cheng, P Maretich, M Blair, H Hagen, MR McReynolds, ... Science advances 7 (46), eabk0271, 2021 | 98 | 2021 |
Skeletal stem cells in space and time M Kassem, P Bianco Cell 160 (1), 17-19, 2015 | 66 | 2015 |
Region-specific proteome changes of the intestinal epithelium during aging and dietary restriction N Gebert, CW Cheng, JM Kirkpatrick, D Di Fraia, J Yun, P Schädel, ... Cell reports 31 (4), 2020 | 59 | 2020 |
Nutritional control of intestinal stem cells in homeostasis and tumorigenesis G Calibasi-Kocal, O Mashinchian, Y Basbinar, E Ellidokuz, CW Cheng, ... Trends in Endocrinology & Metabolism 32 (1), 20-35, 2021 | 30 | 2021 |
Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine CJ Terranova, KM Stemler, P Barrodia, SL Jeter-Jones, Z Ge, ... Cell reports 37 (8), 2021 | 23 | 2021 |
Methods and formulations promoting tissue/organ regeneration, longevity and healthspan VD Longo, CW Cheng, S Brandhorst, M Wei US Patent 10,015,980, 2018 | 17* | 2018 |
Fasting condition as dietary treatment of diabetes VD Longo, CW Cheng US Patent 9,386,790, 2016 | 15 | 2016 |
Egg-Dumping: a Strategy for Host Range Expansion in Callosobruchus maculatus (Coleoptera: Bruchidae) CW Cheng, RL Yang, IC Cheng, SB Horng Annals of the Entomological Society of America 101 (5), 950-954, 2008 | 13 | 2008 |
Cell size is a determinant of stem cell potential during aging. Sci. Adv. 7, eabk0271 J Lengefeld, CW Cheng, P Maretich, M Blair, H Hagen, MR McReynolds, ... | 10 | 2021 |
A novel DNA selection and direct extraction process and its application in DNA recombination AB Wang, CW Cheng, IC Lin, FY Lu, HJ Tsai, CC Lin, CH Yang, PT Pan, ... Electrophoresis 32 (3‐4), 423-430, 2011 | 10 | 2011 |