Ligand–Receptor Binding Affinities from Saturation Transfer Difference (STD) NMR Spectroscopy: The Binding Isotherm of STD Initial Growth Rates J Angulo, PM Enríquez‐Navas, PM Nieto Chemistry-A European Journal 16 (26), 7803-7812, 2010 | 247 | 2010 |
STD-NMR: application to transient interactions between biomolecules—a quantitative approach J Angulo, PM Nieto European biophysics journal 40 (12), 1357-1369, 2011 | 194 | 2011 |
The activation of fibroblast growth factors by heparin: Synthesis, structure, and biological activity of heparin‐like oligosaccharides JL de Paz, J Angulo, JM Lassaletta, PM Nieto, M Redondo‐Horcajo, ... ChemBioChem 2 (9), 673-685, 2001 | 120 | 2001 |
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ... Nature microbiology 4 (12), 2393-2404, 2019 | 112 | 2019 |
Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design M Thépaut, C Guzzi, I Sutkeviciute, S Sattin, R Ribeiro-Viana, N Varga, ... Journal of the American Chemical Society 135 (7), 2518-2529, 2013 | 96 | 2013 |
Differential epitope mapping by STD NMR spectroscopy to reveal the nature of protein–ligand contacts S Monaco, LE Tailford, N Juge, J Angulo Angewandte Chemie International Edition 56 (48), 15289-15293, 2017 | 90 | 2017 |
Blood group B galactosyltransferase: Insights into substrate binding from NMR experiments J Angulo, B Langpap, A Blume, T Biet, B Meyer, NR Krishna, H Peters, ... Journal of the American Chemical Society 128 (41), 13529-13538, 2006 | 89 | 2006 |
Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the 1 C 4 and 2 So conformations of a bioactive heparin … A Canales, J Angulo, R Ojeda, M Bruix, R Fayos, R Lozano, ... Journal of the American Chemical Society 127 (16), 5778-5779, 2005 | 89 | 2005 |
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus CD Owen, LE Tailford, S Monaco, T Šuligoj, L Vaux, R Lallement, ... Nature communications 8 (1), 2196, 2017 | 83 | 2017 |
Gold nanoparticles coated with oligomannosides of HIV-1 glycoprotein gp120 mimic the carbohydrate epitope of antibody 2G12 M Marradi, P Di Gianvincenzo, PM Enríquez-Navas, OM Martínez-Ávila, ... Journal of molecular biology 410 (5), 798-810, 2011 | 81 | 2011 |
Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN J Angulo, I Díaz, JJ Reina, G Tabarani, F Fieschi, J Rojo, PM Nieto ChemBioChem 9 (14), 2225, 2008 | 79 | 2008 |
The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF‐1 J Angulo, R Ojeda, JL de Paz, R Lucas, PM Nieto, RM Lozano, ... ChemBioChem 5 (1), 55-61, 2004 | 78 | 2004 |
Solution NMR structure of a human FGF‐1 monomer, activated by a hexasaccharide heparin‐analogue A Canales, R Lozano, B López‐Méndez, J Angulo, R Ojeda, PM Nieto, ... FEBS Journal 273 (20), 4716-4727, 2006 | 74 | 2006 |
Supramolecular amino acid based hydrogels: probing the contribution of additive molecules using NMR spectroscopy SM Ramalhete, KP Nartowski, N Sarathchandra, JS Foster, AN Round, ... Chemistry–A European Journal 23 (33), 8014-8024, 2017 | 73 | 2017 |
Selective targeting of dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin (DC‐SIGN) with mannose‐based glycomimetics: synthesis and interaction … N Varga, I Sutkeviciute, C Guzzi, J McGeagh, I Petit‐Haertlein, S Gugliotta, ... Chemistry–A European Journal 19 (15), 4786-4797, 2013 | 72 | 2013 |
sp2‐Iminosugar O‐, S‐, and N‐Glycosides as Conformational Mimics of α‐Linked Disaccharides; Implications for Glycosidase Inhibition EM Sánchez‐Fernández, R Rísquez‐Cuadro, C Ortiz Mellet, ... Chemistry–A European Journal 18 (27), 8527-8539, 2012 | 72 | 2012 |
Langerin–heparin interaction: Two binding sites for small and large ligands as revealed by a combination of nmr spectroscopy and cross-linking mapping experiments JC Muñoz-García, E Chabrol, RR Vives, A Thomas, JL de Paz, J Rojo, ... Journal of the American Chemical Society 137 (12), 4100-4110, 2015 | 71 | 2015 |
Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties B Bertrand, J Fernandez-Cestau, J Angulo, MMD Cominetti, ZAE Waller, ... Inorganic Chemistry 56 (10), 5728-5740, 2017 | 64 | 2017 |
A Solution NMR Study of the Interactions of Oligomannosides and the Anti‐HIV‐1 2G12 Antibody Reveals Distinct Binding Modes for Branched Ligands PM Enríquez‐Navas, M Marradi, D Padro, J Angulo, S Penadés Chemistry–A European Journal 17 (5), 1547-1560, 2011 | 61 | 2011 |
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins JB Park, YH Kim, Y Yoo, J Kim, SH Jun, JW Cho, S El Qaidi, S Walpole, ... Nature communications 9 (1), 4283, 2018 | 60 | 2018 |