A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera C James, V Ugo, JP Le Couédic, J Staerk, F Delhommeau, C Lacout, ... nature 434 (7037), 1144-1148, 2005 | 4596 | 2005 |
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency S Hacein-Bey-Abina, C Von Kalle, M Schmidt, F Le Deist, N Wulffraat, ... New England journal of medicine 348 (3), 255-256, 2003 | 2441 | 2003 |
Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients U Duhrsen, JL Villeval, J Boyd, G Kannourakis, G Morstyn, D Metcalf | 787 | 1988 |
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis C Lacout, DF Pisani, M Tulliez, FM Gachelin, W Vainchenker, JL Villeval blood 108 (5), 1652-1660, 2006 | 559 | 2006 |
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily M Jandrot-Perrus, S Busfield, AH Lagrue, X Xiong, N Debili, T Chickering, ... Blood, The Journal of the American Society of Hematology 96 (5), 1798-1807, 2000 | 364 | 2000 |
High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice JL Villeval, K Cohen-Solal, M Tulliez, S Giraudier, J Guichard, SA Burstein, ... Blood, The Journal of the American Society of Hematology 90 (11), 4369-4383, 1997 | 318 | 1997 |
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH Brugman, ... The Journal of clinical investigation 117 (8), 2225-2232, 2007 | 296 | 2007 |
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis C Marty, C Pecquet, H Nivarthi, M El-Khoury, I Chachoua, M Tulliez, ... Blood, The Journal of the American Society of Hematology 127 (10), 1317-1324, 2016 | 291 | 2016 |
Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2 P Lecine, JE Italiano Jr, SW Kim, JL Villeval, RA Shivdasani Blood, The Journal of the American Society of Hematology 96 (4), 1366-1373, 2000 | 235 | 2000 |
Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to … P Lecine, JL Villeval, P Vyas, B Swencki, Y Xu, RA Shivdasani Blood, The Journal of the American Society of Hematology 92 (5), 1608-1616, 1998 | 216 | 1998 |
JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders I Plo, M Nakatake, L Malivert, JP de Villartay, S Giraudier, JL Villeval, ... Blood, The Journal of the American Society of Hematology 112 (4), 1402-1412, 2008 | 198 | 2008 |
Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice C Marty, C Lacout, A Martin, S Hasan, S Jacquot, MC Birling, ... Blood, The Journal of the American Society of Hematology 116 (5), 783-787, 2010 | 192 | 2010 |
A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression C Marty, C Lacout, N Droin, JP Le Couédic, V Ribrag, E Solary, ... Leukemia 27 (11), 2187-2195, 2013 | 188 | 2013 |
Ultrastructural localization of lactoferrin and myeloperoxidase in human neutrophils by immunogold E Cramer, KB Pryzwansky, JL Villeval, U Testa, J Breton-Gorius | 186 | 1985 |
Activating mutations in human acute megakaryoblastic leukemia S Malinge, C Ragu, V Della-Valle, D Pisani, SN Constantinescu, C Perez, ... Blood, The Journal of the American Society of Hematology 112 (10), 4220-4226, 2008 | 168 | 2008 |
JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα S Hasan, C Lacout, C Marty, M Cuingnet, E Solary, W Vainchenker, ... Blood, The Journal of the American Society of Hematology 122 (8), 1464-1477, 2013 | 160 | 2013 |
Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia S Malinge, R Ben-Abdelali, C Settegrana, I Radford-Weiss, M Debre, ... Blood 109 (5), 2202-2204, 2007 | 152 | 2007 |
A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors P Edelman, G Vinci, JL Villeval, W Vainchenker, A Henri, R Miglierina, ... | 148 | 1986 |
Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2 J Levin, JP Peng, GR Baker, JL Villeval, P Lecine, SA Burstein, ... Blood, The Journal of the American Society of Hematology 94 (9), 3037-3047, 1999 | 128 | 1999 |
Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease M Dorsch, G Zheng, D Yowe, P Rao, Y Wang, Q Shen, C Murphy, X Xiong, ... Blood, The Journal of the American Society of Hematology 100 (6), 2046-2055, 2002 | 126 | 2002 |