Genetically programmed chiral organoborane synthesis SBJ Kan, X Huang, Y Gumulya, K Chen, FH Arnold Nature 552 (7683), 132-136, 2017 | 282 | 2017 |
Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods MT Reetz, S Prasad, JD Carballeira, Y Gumulya, M Bocola Journal of the American Chemical Society 132 (26), 9144-9152, 2010 | 259 | 2010 |
Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method MT Reetz, P Soni, L Fernández, Y Gumulya, JD Carballeira Chemical communications 46 (45), 8657-8658, 2010 | 195 | 2010 |
Recent progress in biohydrometallurgy and microbial characterisation AH Kaksonen, NJ Boxall, Y Gumulya, HN Khaleque, C Morris, T Bohu, ... Hydrometallurgy 180, 7-25, 2018 | 179 | 2018 |
Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates J Sanchis, L Fernández, JD Carballeira, J Drone, Y Gumulya, ... Applied microbiology and biotechnology 81, 387-397, 2008 | 155 | 2008 |
Exploring the past and the future of protein evolution with ancestral sequence reconstruction: the ‘retro’approach to protein engineering Y Gumulya, EMJ Gillam Biochemical Journal 474 (1), 1-19, 2017 | 142 | 2017 |
In a quest for engineering acidophiles for biomining applications: challenges and opportunities Y Gumulya, NJ Boxall, HN Khaleque, V Santala, RP Carlson, ... Genes 9 (2), 116, 2018 | 88 | 2018 |
Prospective directions for biohydrometallurgy AH Kaksonen, X Deng, T Bohu, L Zea, HN Khaleque, Y Gumulya, ... Hydrometallurgy 195, 105376, 2020 | 83 | 2020 |
Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima Y Gumulya, J Sanchis, MT Reetz ChemBioChem 13 (7), 1060-1066, 2012 | 83 | 2012 |
Enhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathways Y Gumulya, MT Reetz ChemBioChem 12 (16), 2502-2510, 2011 | 71 | 2011 |
Urban mining of lithium-ion batteries in Australia: Current state and future trends NJ Boxall, S King, KY Cheng, Y Gumulya, W Bruckard, AH Kaksonen Minerals Engineering 128, 45-55, 2018 | 59 | 2018 |
Evaluation of the laccase from Myceliophthora thermophila as industrial biocatalyst for polymerization reactions F Hollmann, Y Gumulya, C Tölle, A Liese, O Thum Macromolecules 41 (22), 8520-8524, 2008 | 58 | 2008 |
Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ... Database 2019, 2019 | 36 | 2019 |
Toward sustainable space exploration: a roadmap for harnessing the power of microorganisms R Santomartino, NJH Averesch, M Bhuiyan, CS Cockell, J Colangelo, ... Nature communications 14 (1), 1391, 2023 | 32 | 2023 |
In situ resource utilisation: the potential for space biomining Y Gumulya, L Zea, AH Kaksonen Minerals Engineering 176, 107288, 2022 | 27 | 2022 |
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP) G Foley, A Mora, CM Ross, S Bottoms, L Sützl, ML Lamprecht, J Zaugg, ... PLOS Computational Biology 18 (10), e1010633, 2022 | 25 | 2022 |
Determinants of thermostability in the cytochrome P450 fold KL Harris, RES Thomson, SJ Strohmaier, Y Gumulya, EMJ Gillam Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (1), 97-115, 2018 | 24 | 2018 |
Learning epistatic interactions from sequence-activity data to predict enantioselectivity J Zaugg, Y Gumulya, AK Malde, M Bodén Journal of computer-aided molecular design 31 (12), 1085-1096, 2017 | 24 | 2017 |
Engineering thermostable CYP2D enzymes for biocatalysis using combinatorial libraries of ancestors for directed evolution (CLADE) Y Gumulya, W Huang, SA D'Cunha, KE Richards, RES Thomson, ... ChemCatChem 11 (2), 841-850, 2019 | 20 | 2019 |
Iridium-Catalyzed Asymmetric C–H Borylation Enabled by Chiral Bidentate Boryl Ligands Y Shi, Q Gao, S Xu Synlett 30 (19), 2107-2112, 2019 | 15 | 2019 |