Molecular basis of acute cystitis reveals susceptibility genes and immunotherapeutic targets I Ambite, M Puthia, K Nagy, C Cafaro, A Nadeem, DSC Butler, G Rydström, ... PLoS pathogens 12 (10), e1005848, 2016 | 56 | 2016 |
IRF7 inhibition prevents destructive innate immunity—A target for nonantibiotic therapy of bacterial infections M Puthia, I Ambite, C Cafaro, D Butler, Y Huang, N Lutay, G Rydström, ... Science Translational Medicine 8 (336), 336ra59-336ra59, 2016 | 42 | 2016 |
Molecular determinants of disease severity in urinary tract infection I Ambite, D Butler, MLY Wan, T Rosenblad, TH Tran, SM Chao, ... Nature Reviews Urology 18 (8), 468-486, 2021 | 40 | 2021 |
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer DSC Butler, C Cafaro, J Putze, MLY Wan, TH Tran, I Ambite, S Ahmadi, ... Nature Biotechnology 39 (6), 754-764, 2021 | 31 | 2021 |
Cytoprotective Effect of Lactobacillus crispatus CTV-05 against Uropathogenic E. coli DSC Butler, A Silvestroni, AE Stapleton Pathogens 5 (1), 27, 2016 | 30 | 2016 |
Neuroepithelial control of mucosal inflammation in acute cystitis DSC Butler, I Ambite, K Nagy, C Cafaro, A Ahmed, A Nadeem, N Filenko, ... Scientific Reports 8 (1), 11015, 2018 | 28 | 2018 |
Immunomodulation therapy offers new molecular strategies to treat UTI D Butler, I Ambite, MLY Wan, TH Tran, B Wullt, C Svanborg Nature Reviews Urology 19 (7), 419-437, 2022 | 26 | 2022 |
Fimbriae reprogram host gene expression–Divergent effects of P and type 1 fimbriae I Ambite, DSC Butler, C Stork, J Grönberg-Hernández, B Köves, ... PLoS pathogens 15 (6), e1007671, 2019 | 24 | 2019 |
Triggered urine interleukin-6 correlates to severity of symptoms in nonfebrile lower urinary tract infections F Sundén, D Butler, B Wullt The Journal of urology 198 (1), 107-115, 2017 | 24 | 2017 |
Epsilon toxin–producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege Y Ma, D Sannino, JR Linden, S Haigh, B Zhao, JB Grigg, P Zumbo, ... The Journal of clinical investigation 133 (9), 2023 | 19 | 2023 |
Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex A Brisuda, JCS Ho, PS Kandiyal, JTY Ng, I Ambite, DSC Butler, J Háček, ... Nature communications 12 (1), 3427, 2021 | 19 | 2021 |
Bladder cancer therapy without toxicity—a dose‐escalation study of alpha1‐oleate TT Hien, I Ambite, D Butler, MLY Wan, TH Tran, U Höglund, M Babjuk, ... International journal of cancer 147 (9), 2479-2492, 2020 | 16 | 2020 |
One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections BX Wang, DSC Butler, M Hamblin, DM Monack Current opinion in microbiology 72, 102262, 2023 | 14 | 2023 |
Immunomodulation—a molecular solution to treating patients with severe bladder pain syndrome? B Wullt, DSC Butler, I Ambite, J Kinsolving, C Krintel, C Svanborg European urology open science 31, 49-58, 2021 | 10 | 2021 |
Active bacterial modification of the host environment through RNA polymerase II inhibition I Ambite, NA Filenko, E Zaldastanishvili, DSC Butler, TH Tran, ... The Journal of Clinical Investigation 131 (4), 2021 | 8 | 2021 |
Phytotherapy (BNO 1045) of acute lower uncomplicated urinary tract infection in women normalizes local host responses DSCBF Wagenlehnerb, M Höllerc, DASHS Kurt, G Naberd Urol. Int 107, 778-784, 2023 | 7 | 2023 |
Molecular mechanisms and immunomodulatory approaches in acute cystitis D Butler Lund University, Faculty of Medicine Doctoral Dissertation Series, 2020 | 1 | 2020 |
Transcriptional profiling links unique human macrophage phenotypes to the growth of intracellular Salmonella enterica serovar Typhi R Schade, DSC Butler, JA McKenna, B Di Luccia, V Shokoohi, M Hamblin, ... Scientific Reports 14 (1), 12811, 2024 | | 2024 |
Therapeutic Effects of IL-1RA against Acute Bacterial Infections, including Antibiotic-Resistant Strains I Ambite, TH Tran, DSC Butler, M Cavalera, MLY Wan, S Ahmadi, ... Pathogens 13 (1), 42, 2023 | | 2023 |
Temporal profiling of Salmonella transcriptional dynamics during macrophage infection using a comprehensive reporter library TH Nguyen, OR Diaz, M Rajendram, DSC Butler, BX Wang, JCD Hinton, ... bioRxiv, 2023.09. 27.559620, 2023 | | 2023 |