关注
Marco Schmidt
Marco Schmidt
未知所在单位机构
在 biotx.ai 的电子邮件经过验证
标题
引用次数
引用次数
年份
Drug target miRNAs: chances and challenges
MF Schmidt
Trends in biotechnology 32 (11), 578-585, 2014
1572014
Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease
L Zhu, S George, MF Schmidt, SI Al-Gharabli, J Rademann, R Hilgenfeld
Antiviral research 92 (2), 204-212, 2011
1372011
Sensitized detection of inhibitory fragments and iterative development of non‐peptidic protease inhibitors by dynamic ligation screening
MF Schmidt, A Isidro‐Llobet, M Lisurek, A El‐Dahshan, J Tan, ...
Angewandte Chemie International Edition 47 (17), 3275-3278, 2008
872008
An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS‐CoV Mpro) inhibitors
SI Al‐Gharabli, STA Shah, S Weik, MF Schmidt, JR Mesters, D Kuhn, ...
ChemBioChem 7 (7), 1048-1055, 2006
772006
Dynamic template-assisted strategies in fragment-based drug discovery
MF Schmidt, J Rademann
Trends in biotechnology 27 (9), 512-521, 2009
692009
Design, synthesis, and qualitative structure–activity evaluations of novel β-Secretase inhibitors as potential Alzheimer’s drug leads
TH Al-Tel, MH Semreen, RA Al-Qawasmeh, MF Schmidt, R El-Awadi, ...
Journal of medicinal chemistry 54 (24), 8373-8385, 2011
622011
Selective identification of cooperatively binding fragments in a high‐throughput ligation assay enables development of a picomolar caspase‐3 inhibitor
MF Schmidt, A El‐Dahshan, S Keller, J Rademann
Angewandte Chemie International Edition 48 (34), 6346-6349, 2009
572009
Rational design and synthesis of potent dibenzazepine motifs as β-secretase inhibitors
TH Al-Tel, RA Al-Qawasmeh, MF Schmidt, A Al-Aboudi, SN Rao, SS Sabri, ...
Journal of medicinal chemistry 52 (20), 6484-6488, 2009
472009
MicroRNA-specific argonaute 2 protein inhibitors
MF Schmidt, O Korb, C Abell
ACS chemical biology 8 (10), 2122-2126, 2013
432013
Dynamic Substrate Enhancement for the Identification of Specific, Second‐Site‐Binding Fragments Targeting a Set of Protein Tyrosine Phosphatases
MF Schmidt, MR Groves, J Rademann
ChemBioChem 12 (17), 2640-2646, 2011
342011
miRNA targeting drugs: the next blockbusters?
MF Schmidt
Drug Target miRNA: Methods and Protocols, 3-22, 2017
282017
Sensibilisierte Detektion inhibitorischer Fragmente und iterative Entwicklung nicht‐peptidischer Proteaseinhibitoren durch dynamisches Ligationsscreening
MF Schmidt, A Isidro‐Llobet, M Lisurek, A El‐Dahshan, J Tan, ...
Angewandte Chemie 120 (17), 3319-3323, 2008
282008
Selektive Detektion kooperativ bindender Fragmente in einem Hochdurchsatz-Ligationsassay zur Entwicklung eines pikomolaren Caspase-3-Inhibitors
MF Schmidt, A El-Dahshan, S Keller, J Rademann
Angew. Chem 121, 6464-6467, 2009
202009
Discovery of Schaeffer's acid analogues as lead structures of mycobacterium tuberculosis type II dehydroquinase using a rational drug design approach.
MF Schmidt, O Korb, NI Howard, MV Dias, TL Blundell, C Abell
ChemMedChem 8 (1), 54-58, 2012
172012
Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis
NI Howard, MVB Dias, F Peyrot, L Chen, MF Schmidt, TL Blundell, C Abell
ChemMedChem 10 (1), 116-133, 2015
132015
Interaction-based feature selection algorithm outperforms polygenic risk score in predicting Parkinson’s disease status
JL Cope, HA Baukmann, JE Klinger, CNJ Ravarani, EP Böttinger, ...
Frontiers in genetics 12, 744557, 2021
82021
Critically ill COVID-19 status associated trait genetics reveals CDK6 inhibitors as potential treatment
J Klinger, C Ravarani, C Bannard, M Lamparter, A Schwinges, J Cope, ...
32021
Targeting Longevity Gene SLC13A5: A Novel Approach to Prevent Age-Related Bone Fragility and Osteoporosis
G Zahn, HA Baukmann, J Wu, J Jordan, AL Birkenfeld, N Dirckx, ...
Metabolites 13 (12), 1186, 2023
22023
Neutrophils cause critical illness in COVID-19 and reveal CDK6 inhibitors as potential treatment
HA Baukmann, JL Cope, CNJ Ravarani, C Bannard, MRJ Lamparter, ...
MedRxiv, 2021.05. 18.21256584, 2021
22021
CHEMISCHE BIOLOGIE: und wirkstoffentwicklung
MF Schmidt
Springer Spektrum, 2020
22020
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