Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, ... Nature medicine 23 (7), 878-884, 2017 | 351 | 2017 |
A modular platform for differentiation of human PSCs into all major ectodermal lineages J Tchieu, B Zimmer, F Fattahi, S Amin, N Zeltner, S Chen, L Studer Cell stem cell 21 (3), 399-410. e7, 2017 | 203 | 2017 |
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ... Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013 | 184 | 2013 |
Genome editing in hPSCs reveals GATA6 haploinsufficiency and a genetic interaction with GATA4 in human pancreatic development ZD Shi, K Lee, D Yang, S Amin, N Verma, QV Li, Z Zhu, CL Soh, R Kumar, ... Cell stem cell 20 (5), 675-688. e6, 2017 | 160 | 2017 |
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells Z Ghazizadeh, DI Kao, S Amin, B Cook, S Rao, T Zhou, T Zhang, Z Xiang, ... Nature communications 8 (1), 298, 2017 | 87 | 2017 |
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience JC Udeochu, S Amin, Y Huang, L Fan, ERS Torres, GK Carling, B Liu, ... Nature neuroscience 26 (5), 737-750, 2023 | 65 | 2023 |
Modeling cystic fibrosis using pluripotent stem cell-derived human pancreatic ductal epithelial cells S Simsek, T Zhou, CL Robinson, SY Tsai, M Crespo, S Amin, X Lin, J Hon, ... Stem cells translational medicine 5 (5), 572-579, 2016 | 56 | 2016 |
Discovery of a drug candidate for GLIS3-associated diabetes S Amin, B Cook, T Zhou, Z Ghazizadeh, R Lis, T Zhang, M Khalaj, ... Nature communications 9 (1), 2681, 2018 | 55 | 2018 |
FOXC1 in human trabecular meshwork cells is involved in regulatory pathway that includes miR-204, MEIS2, and ITGβ1 SH Paylakhi, H Moazzeni, S Yazdani, P Rassouli, E Arefian, E Jaberi, ... Experimental Eye Research 111, 112-121, 2013 | 55 | 2013 |
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badieyan, ... Nature Communications 9 (1), 4815, 2018 | 32 | 2018 |
A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity SY Tsai, Z Ghazizadeh, HJ Wang, A Sadaf, FA Ortega, ZS Badieyan, ... Cardiovascular research, 2019 | 20 | 2019 |
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy H Majd, S Amin, Z Ghazizadeh, A Cesiulis, E Arroyo, K Lankford, A Majd, ... Cell Stem Cell 30 (5), 632-647. e10, 2023 | 18 | 2023 |
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia S Amin, G Carling, L Gan Current Opinion in Neurobiology 72, 131-139, 2022 | 18 | 2022 |
MicroRNAs that target RGS5 A Banaei-Esfahani, H Moazzeni, PN Nosar, S Amin, E Arefian, ... Iranian journal of basic medical sciences 18 (2), 108, 2015 | 12 | 2015 |
Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders Y Huang, B Liu, SC Sinha, S Amin, L Gan Molecular Neurodegeneration 18 (1), 79, 2023 | 6 | 2023 |
Autophagy prevents microglial senescence S Amin, B Liu, L Gan Nature Cell Biology 25, 923–925, 2023 | 4 | 2023 |
A dual SHOX2: GFP; MYH6: mCherry knockin hESC reporter line for derivation of human SAN-like cells Z Ghazizadeh, J Zhu, F Fattahi, A Tang, X Sun, S Amin, SY Tsai, M Khalaj, ... Iscience 25 (4), 2022 | 3 | 2022 |
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model GK Carling, L Fan, NR Foxe, K Norman, P Ye, MY Wong, D Zhu, F Yu, ... bioRxiv, 2024.01. 24.577107, 2024 | 1 | 2024 |
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity H Chen, L Fan, Q Guo, MY Wong, F Yu, N Foxe, W Wang, A Nessim, ... Research Square, 2023 | | 2023 |
A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells L Tan, X Duan, P Mutyala, T Zhou, S Amin, T Zhang, B Herbst, G Askan, ... Journal of Molecular Cell Biology 15 (6), mjad039, 2023 | | 2023 |