Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance SR Amend, G Torga, KC Lin, LG Kostecka, A de Marzo, RH Austin, ... The Prostate 79 (13), 1489-1497, 2019 | 157 | 2019 |
The role of heterogeneous environment and docetaxel gradient in the emergence of polyploid, mesenchymal and resistant prostate cancer cells KC Lin, G Torga, Y Sun, R Axelrod, KJ Pienta, JC Sturm, RH Austin Clinical & experimental metastasis 36, 97-108, 2019 | 64 | 2019 |
Bacterial route finding and collective escape in mazes and fractals TV Phan, R Morris, ME Black, TK Do, KC Lin, K Nagy, JC Sturm, J Bos, ... Physical Review X 10 (3), 031017, 2020 | 33 | 2020 |
Epithelial and mesenchymal prostate cancer cell population dynamics on a complex drug landscape KC Lin, G Torga, A Wu, JD Rabinowitz, WJ Murray, JC Sturm, KJ Pienta, ... Convergent science physical oncology 3 (4), 045001, 2017 | 13 | 2017 |
High-throughput optofluidic screening for improved microbial cell factories via real-time micron-scale productivity monitoring M Rienzo, KC Lin, KC Mobilia, EK Sackmann, V Kurz, AH Navidi, J King, ... Lab on a Chip 21 (15), 2901-2912, 2021 | 11 | 2021 |
Cancer dormancy and criticality from a game theory perspective A Wu, D Liao, V Kirilin, KC Lin, G Torga, J Qu, L Liu, JC Sturm, K Pienta, ... Cancer convergence 2, 1-8, 2018 | 11 | 2018 |
An in vitro tumor swamp model of heterogeneous cellular and chemotherapeutic landscapes KC Lin, Y Sun, G Torga, P Sherpa, Y Zhao, J Qu, SR Amend, KJ Pienta, ... Lab on a Chip 20 (14), 2453-2464, 2020 | 10 | 2020 |
Bacterial population solitary waves can defeat rings of funnels RJ Morris, TV Phan, M Black, KC Lin, IG Kevrekidis, JA Bos, RH Austin New Journal of Physics 19 (3), 035002, 2017 | 9 | 2017 |
The emergence of polyploid giant cancer cells as the reservoir of theraputic resistance KC Lin, G Torga, J Sturm, K Pienta, R Austin APS march meeting abstracts 2018, V46. 003, 2018 | 4 | 2018 |
Generation of heterogeneous drug gradients across cancer populations on a microfluidic evolution accelerator for real-time observation KC Lin, G Torga, Y Sun, KJ Pienta, JC Sturm, RH Austin Journal of Visualized Experiments, 2019 | 3 | 2019 |
Methods of Microfluidic Assay and Bioproduction from Non-Mammalian Cells and Kits Therefor O Gadish, KC Mobilia, S Tafoya, EK Sackmann, AJ Mastroianni, P Shieh, ... US Patent App. 18/481,448, 2024 | | 2024 |
Method for assaying a micro-object within a microfluidic device AJ Mastroianni, P Shieh, KC Mobilia, EK Sackmann, KC Lin, O Gadish, ... US Patent App. 18/126,845, 2023 | | 2023 |
Systems and apparatuses for cellular therapeutics manufacture AW McFarland, PJ Beemiller, GK Stadler, AJ Mastroianni, JJC RIVERA, ... US Patent App. 18/147,356, 2023 | | 2023 |
Systems, apparatuses, and methods for cellular therapeutics manufacture AW McFarland, PJ Beemiller, GK Stadler, AJ Mastroianni, JJC RIVERA, ... US Patent App. 17/574,459, 2022 | | 2022 |
Evolutionary dynamics of cancer on complex stress landscapes Y Sun, KC Lin, T Phan, G Torga, S Amend, K Pienta, J Sturm, R Austin Bulletin of the American Physical Society 65, 2020 | | 2020 |
Elevated cancer evolution dynamics: Emergence of polyploid cancer cells in response to multimodal therapy as an adaptive response on both individual and collective levels G Torga, KC Lin, K Myers, K Smith, RH Austin, KJ Pienta Cancer Research 79 (13_Supplement), 3774-3774, 2019 | | 2019 |
Cancer Dynamics under a Chemotherapeutic Stress Gradient Using a Microfluidic in vitro Tumor Environment KC Lin Princeton University, 2019 | | 2019 |
Understand the role of chemotherapeutic gradient in the emergence of polyploid giant cancer cells using mean field model KC Lin, G Torga, Y Sun, R Axelrod, K Pienta, J Sturm, R Austin APS March Meeting Abstracts 2019, P23. 004, 2019 | | 2019 |
Measurement of In vitro Cancer Tumor Hypoxia Y Zhao, R Austin, KC Lin, J Sturm, J Qu APS March Meeting Abstracts 2019, L30. 011, 2019 | | 2019 |
Abstract B039: Multinucleation precedes the emergence of drug resistance in prostate cancer G Torga, KC Lin, RH Austin, KJ Pienta Cancer Research 78 (16_Supplement), B039-B039, 2018 | | 2018 |