Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish AH Meijer, SFG Krens, IAM Rodriguez, S He, W Bitter, BE Snaar-Jagalska, ... Molecular immunology 40 (11), 773-783, 2004 | 623 | 2004 |
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ... Nature genetics 50 (9), 1240-1246, 2018 | 232 | 2018 |
MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification MW Zimmerman, Y Liu, S He, AD Durbin, BJ Abraham, J Easton, Y Shao, ... Cancer discovery 8 (3), 320-335, 2018 | 205 | 2018 |
Neutrophil‐mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model S He, GEM Lamers, JWM Beenakker, C Cui, VPS Ghotra, EHJ Danen, ... The Journal of pathology 227 (4), 431-445, 2012 | 205 | 2012 |
Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model Y Drabsch, S He, L Zhang, BE Snaar-Jagalska, P ten Dijke Breast Cancer Research 15, 1-13, 2013 | 133 | 2013 |
The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells Z Li, S He, AT Look Leukemia 33 (1), 262-266, 2019 | 130 | 2019 |
β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer HH Truong, J Xiong, VPS Ghotra, E Nirmala, L Haazen, SE Le Dévédec, ... Science signaling 7 (312), ra15-ra15, 2014 | 122 | 2014 |
Automated whole animal bio-imaging assay for human cancer dissemination VPS Ghotra, S He, H de Bont, W van Der Ent, HP Spaink, B van De Water, ... PloS one 7 (2), e31281, 2012 | 103 | 2012 |
Characterization and expression patterns of the MAPK family in zebrafish SFG Krens, S He, HP Spaink, BE Snaar-Jagalska Gene expression patterns 6 (8), 1019-1026, 2006 | 103 | 2006 |
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo C Dubiella, BJ Pinch, K Koikawa, D Zaidman, E Poon, TD Manz, B Nabet, ... Nature chemical biology 17 (9), 954-963, 2021 | 98 | 2021 |
Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development J Shin, A Padmanabhan, ED De Groh, JS Lee, S Haidar, S Dahlberg, ... Disease models & mechanisms 5 (6), 881-894, 2012 | 98 | 2012 |
LMO1 synergizes with MYCN to promote neuroblastoma initiation and metastasis S Zhu, X Zhang, N Weichert-Leahey, Z Dong, C Zhang, G Lopez, T Tao, ... Cancer cell 32 (3), 310-323. e5, 2017 | 95 | 2017 |
Discovery of a selective inhibitor of doublecortin like kinase 1 FM Ferguson, B Nabet, S Raghavan, Y Liu, AL Leggett, M Kuljanin, ... Nature chemical biology 16 (6), 635-643, 2020 | 94 | 2020 |
Retracted: allosteric activators of protein phosphatase 2a display broad antitumor activity mediated by dephosphorylation of MYBL2 K Morita, S He, RP Nowak, J Wang, MW Zimmerman, C Fu, AD Durbin, ... Cell 181 (3), 702-715. e20, 2020 | 94 | 2020 |
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ... Nature communications 7 (1), 10358, 2016 | 90 | 2016 |
Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation SFG Krens, S He, GEM Lamers, AH Meijer, J Bakkers, T Schmidt, ... Developmental biology 319 (2), 370-383, 2008 | 85 | 2008 |
ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis SFG Krens, M Corredor-Adámez, S He, BE Snaar-Jagalska, HP Spaink BMC genomics 9, 1-21, 2008 | 72 | 2008 |
A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing E Gjini, MR Mansour, JD Sander, N Moritz, AT Nguyen, M Kesarsing, ... Molecular and cellular biology, 2015 | 71 | 2015 |
SYK is a candidate kinase target for the treatment of advanced prostate cancer VPS Ghotra, S He, G Van Der Horst, S Nijhoff, H de Bont, A Lekkerkerker, ... Cancer research 75 (1), 230-240, 2015 | 68 | 2015 |
Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish S Camus, C Quevedo, S Menéndez, I Paramonov, PFW Stouten, ... Oncogene 31 (39), 4333-4342, 2012 | 61 | 2012 |