Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial MD Tameris, M Hatherill, BS Landry, TJ Scriba, MA Snowden, S Lockhart, ... The Lancet 381 (9871), 1021-1028, 2013 | 1196 | 2013 |
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete, H Tegally, JE San, ... Nature 602 (7898), 654-656, 2022 | 1039 | 2022 |
A blood RNA signature for tuberculosis disease risk: a prospective cohort study DE Zak, A Penn-Nicholson, TJ Scriba, E Thompson, S Suliman, LM Amon, ... The Lancet 387 (10035), 2312-2322, 2016 | 768 | 2016 |
Escape of SARS-CoV-2 501Y. V2 from neutralization by convalescent plasma S Cele, I Gazy, L Jackson, SH Hwa, H Tegally, G Lustig, J Giandhari, ... Nature 593 (7857), 142-146, 2021 | 674 | 2021 |
Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination E Nemes, H Geldenhuys, V Rozot, KT Rutkowski, F Ratangee, N Bilek, ... New England Journal of Medicine 379 (2), 138-149, 2018 | 649 | 2018 |
Immunological biomarkers of tuberculosis G Walzl, K Ronacher, W Hanekom, TJ Scriba, A Zumla Nature Reviews Immunology 11 (5), 343-354, 2011 | 646 | 2011 |
Distinct, specific IL-17-and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response TJ Scriba, B Kalsdorf, DA Abrahams, F Isaacs, J Hofmeister, G Black, ... The Journal of Immunology 180 (3), 1962-1970, 2008 | 546 | 2008 |
Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns BMN Kagina, B Abel, TJ Scriba, EJ Hughes, A Keyser, A Soares, ... American journal of respiratory and critical care medicine 182 (8), 1073-1079, 2010 | 501 | 2010 |
Dominant TNF-α+Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease A Harari, V Rozot, FB Enders, M Perreau, JM Stalder, LP Nicod, ... Nature medicine 17 (3), 372-376, 2011 | 492 | 2011 |
Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load CL Day, DA Abrahams, L Lerumo, E Janse van Rensburg, L Stone, ... The Journal of Immunology 187 (5), 2222-2232, 2011 | 411 | 2011 |
T cells and adaptive immunity to Mycobacterium tuberculosis in humans LD Jasenosky, TJ Scriba, WA Hanekom, AE Goldfeld Immunological reviews 264 (1), 74-87, 2015 | 398 | 2015 |
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete, H Tegally, JE San, ... MedRxiv, 2021 | 365 | 2021 |
The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults B Abel, M Tameris, N Mansoor, S Gelderbloem, J Hughes, D Abrahams, ... American journal of respiratory and critical care medicine 181 (12), 1407-1417, 2010 | 316 | 2010 |
T-cell activation is an immune correlate of risk in BCG vaccinated infants HA Fletcher, MA Snowden, B Landry, W Rida, I Satti, SA Harris, ... Nature communications 7 (1), 11290, 2016 | 296 | 2016 |
Bacillus Calmette-Guerin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles AP Soares, TJ Scriba, S Joseph, R Harbacheuski, RA Murray, ... The Journal of Immunology 180 (5), 3569-3577, 2008 | 293 | 2008 |
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells LJ Walker, YH Kang, MO Smith, H Tharmalingham, N Ramamurthy, ... Blood, The Journal of the American Society of Hematology 119 (2), 422-433, 2012 | 290 | 2012 |
Influence of BCG vaccine strain on the immune response and protection against tuberculosis N Ritz, WA Hanekom, R Robins-Browne, WJ Britton, N Curtis FEMS microbiology reviews 32 (5), 821-841, 2008 | 269 | 2008 |
Four-gene pan-African blood signature predicts progression to tuberculosis S Suliman, EG Thompson, J Sutherland, J Weiner 3rd, MOC Ota, ... American journal of respiratory and critical care medicine 197 (9), 1198-1208, 2018 | 266 | 2018 |
COMPASS identifies T-cell subsets correlated with clinical outcomes L Lin, G Finak, K Ushey, C Seshadri, TR Hawn, N Frahm, TJ Scriba, ... Nature biotechnology 33 (6), 610-616, 2015 | 265 | 2015 |
Modified vaccinia Ankara‐expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells TJ Scriba, M Tameris, N Mansoor, E Smit, L van der Merwe, F Isaacs, ... European journal of immunology 40 (1), 279-290, 2010 | 260 | 2010 |