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Changyoun Kim, PhD
Changyoun Kim, PhD
National Institute on Aging / National Institutes of Health
在 nih.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
C Kim, DH Ho, JE Suk, S You, S Michael, J Kang, S Joong Lee, E Masliah, ...
Nat Communications 4, 1562, 2013
8072013
A compendium of promoter-centered long-range chromatin interactions in the human genome
I Jung, A Schmitt, Y Diao, AJ Lee, T Liu, D Yang, C Tan, J Eom, M Chan, ...
Nature genetics 51 (10), 1442-1449, 2019
2992019
Alpha-synuclein stimulation of astrocytes: potential role for neuroinflammation and neuroprotection
HJ Lee, C Kim, SJ Lee
Oxidative medicine and cellular longevity 3 (4), 283-287, 2010
1602010
LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation
EJ Bae, DK Kim, C Kim, M Mante, A Adame, E Rockenstein, A Ulusoy, ...
Nature communications 9 (1), 3465, 2018
1462018
Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril
C Kim, G Lv, JS Lee, BC Jung, M Masuda-Suzukake, CS Hong, E Valera, ...
Scientific reports 6 (1), 30891, 2016
1462016
Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy
Kim, C., Rockenstein, E., Spencer, B., Kim, H.K., Adame, A., Trejo, M ...
Cell reports 13, 771-782, 2015
1342015
Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation
C Kim, B Spencer, E Rockenstein, H Yamakado, M Mante, A Adame, ...
Molecular neurodegeneration 13 (1), 43, 2018
1332018
Controlling the mass action of α‐synuclein in Parkinson’s disease
C Kim, SJ Lee
Journal of neurochemistry 107 (2), 303-316, 2008
1302008
HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders
Fields, J.A., Serger, E., Campos, S., Divakaruni, A.S., Kim, C., Smith, K ...
Neurobiology of disease 86, 154, 2016
1002016
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
C Kim, HJ Lee, E Masliah, SJ Lee
Experimental neurobiology 25 (3), 113, 2016
932016
Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy
O El-Agnaf, C Overk, E Rockenstein, M Mante, J Florio, A Adame, ...
Neurobiology of disease 104, 85-96, 2017
902017
Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1/2 in rheumatoid fibroblast-like synoviocytes
GC Shin, C Kim, JM Lee, WS Cho, SG Lee, M Jeong, J Cho, K Lee
Chemico-biological interactions 182 (1), 29-36, 2009
782009
β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein
C Kim, ED Cho, HK Kim, S You, HJ Lee, D Hwang, SJ Lee
Experimental & molecular medicine 46 (4), e91-e91, 2014
722014
Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
M Iba, C Kim, M Sallin, S Kwon, A Verma, C Overk, RA Rissman, R Sen, ...
Journal of Neuroinflammation 17, 1-14, 2020
702020
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies
C Kim, A Beilina, N Smith, Y Li, M Kim, R Kumaran, A Kaganovich, ...
Science translational medicine 12 (565), eaay0399, 2020
622020
A new synthetic chalcone derivative, 2-hydroxy-3', 5, 5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of …
YH Lee, SH Jeon, SH Kim, C Kim, SJ Lee, D Koh, Y Lim, K Ha, SY Shin
Experimental & molecular medicine 44 (6), 369-377, 2012
602012
alpha-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy Body disease.
Spencer, B., Kim, C., Gonzalez, T., Bisquertt, A., Patrick, C., Rockenstein ...
Human molecular genetics 25 (6), 1100, 2016
592016
Immunotherapies for aging-related neurodegenerative diseases—emerging perspectives and new targets
S Kwon, M Iba, C Kim, E Masliah
Neurotherapeutics 17 (3), 935-954, 2020
582020
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ...
PLoS biology 19 (12), e3001480, 2021
532021
Glucocerebrosidase Modulates Cognitive and Motor Activities in Murine Models of Parkinson's Disease
SSP Rockenstein E., Clarke J., Viel C., Panarello N., Treleaven C.M., Kim C ...
Human molecular genetics 25 (13), 2645, 2016
512016
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