Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity PT Pang, HK Teng, E Zaitsev, NT Woo, K Sakata, S Zhen, KK Teng, ... Science 306 (5695), 487-491, 2004 | 1357 | 2004 |
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis K Shimazu, M Zhao, K Sakata, S Akbarian, B Bates, R Jaenisch, B Lu Learning & Memory 13 (3), 307-315, 2006 | 248 | 2006 |
Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex K Sakata, NH Woo, K Martinowich, JS Greene, RJ Schloesser, L Shen, ... Proceedings of the National Academy of Sciences 106 (14), 5942-5947, 2009 | 222 | 2009 |
Role of activity-dependent BDNF expression in hippocampal–prefrontal cortical regulation of behavioral perseverance K Sakata, K Martinowich, NH Woo, RJ Schloesser, DV Jimenez, Y Ji, ... Proceedings of the National Academy of Sciences 110 (37), 15103-15108, 2013 | 160 | 2013 |
Cloning of a lymphatic peptide/histidine transporter K SAKATA, T YAMASHITA, M MAEDA, Y MORIYAMA, S SHIMADA, ... Biochemical Journal 356 (1), 53-60, 2001 | 153 | 2001 |
Altered synapse formation in the adult somatosensory cortex of brain-derived neurotrophic factor heterozygote mice C Genoud, GW Knott, K Sakata, B Lu, E Welker Journal of Neuroscience 24 (10), 2394-2400, 2004 | 139 | 2004 |
Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment Y Chen, B Wang, D Liu, JJ Li, Y Xue, K Sakata, L Zhu, SA Heldt, H Xu, ... Journal of Neuroscience 34 (7), 2464-2470, 2014 | 135 | 2014 |
Thioredoxin-interacting protein (TXNIP) associated NLRP3 inflammasome activation in human Alzheimer’s disease brain L Li, S Ismael, S Nasoohi, K Sakata, FF Liao, MP McDonald, T Ishrat Journal of Alzheimer's Disease 68 (1), 255-265, 2019 | 103 | 2019 |
Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice … S Jha, B Dong, K Sakata Translational psychiatry 1 (9), e40-e40, 2011 | 94 | 2011 |
A key mechanism underlying sensory experience-dependent maturation of neocortical GABAergic circuits in vivo Y Jiao, Z Zhang, C Zhang, X Wang, K Sakata, B Lu, QQ Sun Proceedings of the National Academy of Sciences 108 (29), 12131-12136, 2011 | 88 | 2011 |
Lack of promoter IV‐driven BDNF transcription results in depression‐like behavior K Sakata, L Jin, S Jha Genes, Brain and Behavior 9 (7), 712-721, 2010 | 86 | 2010 |
Cerebellar deficits and hyperactivity in mice lacking Smad4 YX Zhou, M Zhao, D Li, K Shimazu, K Sakata, CX Deng, B Lu Journal of Biological Chemistry 278 (43), 42313-42320, 2003 | 81 | 2003 |
Expression pattern of messenger RNAs for prostanoid receptors in glial cell cultures J Kitanaka, H Hashimoto, M Gotoh, K Kondo, K Sakata, Y Hirasawa, ... Brain research 707 (2), 282-287, 1996 | 70 | 1996 |
Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus K Sakata, SM Duke Neuroscience 260, 265-275, 2014 | 59 | 2014 |
Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1 N Mitsuda, N Ohkubo, M Tamatani, YD Lee, M Taniguchi, K Namikawa, ... Journal of Biological Chemistry 276 (13), 9688-9698, 2001 | 55 | 2001 |
Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation E Kim, K Sakata, FF Liao PLoS genetics 13 (7), e1006849, 2017 | 51 | 2017 |
A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer’s mouse model via an HSF1-mediated mechanism B Wang, Y Liu, L Huang, J Chen, JJ Li, R Wang, E Kim, Y Chen, C Justicia, ... Molecular psychiatry 22 (7), 990-1001, 2017 | 49 | 2017 |
ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease S Ismael, K Sakata, MP McDonald, FF Liao, T Ishrat Neurochemistry international 148, 105104, 2021 | 38 | 2021 |
Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV S Jha, BE Dong, Y Xue, DF Delotterie, MG Vail, K Sakata Translational psychiatry 6 (9), e896-e896, 2016 | 38 | 2016 |
BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice A Reiner, HB Wang, N Del Mar, K Sakata, W Yoo, YP Deng Brain research 1473, 161-172, 2012 | 35 | 2012 |