MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li, L Lai, BH Jiang Nucleic acids research 40 (2), 761-774, 2012 | 301 | 2012 |
A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1 Q Xu, Y Jiang, Y Yin, Q Li, J He, Y Jing, YT Qi, Q Xu, W Li, B Lu, SS Peiper, ... Journal of molecular cell biology 5 (1), 3-13, 2013 | 291 | 2013 |
Nucleus-translocated ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy X Li, W Yu, X Qian, Y Xia, Y Zheng, JH Lee, W Li, J Lyu, G Rao, X Zhang, ... Molecular cell 66 (5), 684-697. e9, 2017 | 208 | 2017 |
Phosphoglycerate kinase 1 phosphorylates Beclin1 to induce autophagy X Qian, X Li, Q Cai, C Zhang, Q Yu, Y Jiang, JH Lee, D Hawke, Y Wang, ... Molecular cell 65 (5), 917-931. e6, 2017 | 190 | 2017 |
MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1 Z Shi, J Wang, Z Yan, Y You, C Li, X Qian, Y Yin, P Zhao, Y Wang, ... PloS one 7 (3), e32709, 2012 | 175 | 2012 |
Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis JH Lee, R Liu, J Li, C Zhang, Y Wang, Q Cai, X Qian, Y Xia, Y Zheng, ... Nature communications 8 (1), 1-14, 2017 | 169 | 2017 |
MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers X Qian, J Yu, Y Yin, J He, L Wang, Q Li, LQ Zhang, CY Li, ZM Shi, Q Xu, ... Cell cycle 12 (9), 1385-1394, 2013 | 165 | 2013 |
Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation Y Jiang, X Qian, J Shen, Y Wang, X Li, R Liu, Y Xia, Q Chen, G Peng, ... Nature cell biology 17 (9), 1158-1168, 2015 | 157 | 2015 |
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma L Wang, Z Shi, C Jiang, X Liu, Q Chen, X Qian, D Li, X Ge, X Wang, LZ Liu, ... Oncotarget 5 (14), 5416, 2014 | 140 | 2014 |
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis D Xu, Z Wang, Y Xia, F Shao, W Xia, Y Wei, X Li, X Qian, JH Lee, L Du, ... Nature 580 (7804), 530-535, 2020 | 138 | 2020 |
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras Z Shi, Q Chen, C Li, L Wang, X Qian, C Jiang, X Liu, X Wang, H Li, ... Neuro-oncology 16 (10), 1341-1353, 2014 | 138 | 2014 |
Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR‐199a/125b and DNA methylation J He, Q Xu, Y Jing, F Agani, X Qian, R Carpenter, Q Li, XR Wang, ... EMBO reports 13 (12), 1116-1122, 2012 | 136 | 2012 |
Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis J He, Y Jing, W Li, X Qian, Q Xu, FS Li, LZ Liu, BH Jiang, Y Jiang PloS one 8 (2), e56647, 2013 | 135 | 2013 |
A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation X Li, X Qian, LX Peng, Y Jiang, DH Hawke, Y Zheng, Y Xia, JH Lee, ... Nature cell biology 18 (5), 561-571, 2016 | 124 | 2016 |
EGFR-phosphorylated platelet isoform of phosphofructokinase 1 promotes PI3K activation JH Lee, R Liu, J Li, Y Wang, L Tan, XJ Li, X Qian, C Zhang, Y Xia, D Xu, ... Molecular cell 70 (2), 197-210. e7, 2018 | 104 | 2018 |
Lentivirus-mediated overexpression of microRNA-199a inhibits cell proliferation of human hepatocellular carcinoma XQ Jia, HQ Cheng, X Qian, CX Bian, ZM Shi, JP Zhang, BH Jiang, ... Cell biochemistry and biophysics 62 (1), 237-244, 2012 | 99 | 2012 |
PTEN suppresses glycolysis by dephosphorylating and inhibiting autophosphorylated PGK1 X Qian, X Li, Z Shi, Y Xia, Q Cai, D Xu, L Tan, L Du, Y Zheng, D Zhao, ... Molecular cell 76 (3), 516-527. e7, 2019 | 98 | 2019 |
Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1 Y Yin, ZP Yan, NN Lu, Q Xu, J He, X Qian, J Yu, X Guan, BH Jiang, LZ Liu Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (2), 239-247, 2013 | 97 | 2013 |
Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progression Q Xu, LZ Liu, Y Yin, J He, Q Li, X Qian, Y You, Z Lu, SC Peiper, Y Shu, ... Oncogene 34 (43), 5482-5493, 2015 | 96 | 2015 |
MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas Z Shi, X Wang, X Qian, T Tao, L Wang, Q Chen, X Wang, L Cao, Y Wang, ... Rna 19 (4), 552-560, 2013 | 94 | 2013 |