Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae AE Wright, JC Botelho, E Guzmán, D Harmody, P Linley, PJ McCarthy, ... Journal of natural products 70 (3), 412-416, 2007 | 237 | 2007 |
Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp. I Paterson, SM Dalby, JC Roberts, GJ Naylor, EA Guzmán, R Isbrucker, ... Angewandte Chemie 123 (14), 3277-3281, 2011 | 113 | 2011 |
Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer E Guzman, JL Langowski, L Owen-Schaub Apoptosis 8, 315-325, 2003 | 87 | 2003 |
Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis LA Buhler, R Samara, E Guzman, CL Wilson, L Krizanac-Bengez, ... BMC neuroscience 10, 1-12, 2009 | 76 | 2009 |
The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells G Kallifatidis, D Hoepfner, T Jaeg, EA Guzmán, AE Wright Marine drugs 11 (9), 3500-3516, 2013 | 72 | 2013 |
A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis EA Guzmán, JD Johnson, PA Linley, SE Gunasekera, AE Wright Investigational new drugs 29, 777-785, 2011 | 61 | 2011 |
Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines EA Guzmán, JD Johnson, MK Carrier, CI Meyer, TP Pitts, SP Gunasekera, ... Anti-cancer drugs 20 (2), 149-155, 2009 | 52 | 2009 |
The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells EA Guzmán, K Maers, J Roberts, HV Kemami-Wangun, D Harmody, ... Investigational new drugs 33, 86-94, 2015 | 50 | 2015 |
Mitf dosage as a primary determinant of melanocyte survival after ultraviolet irradiation TJ Hornyak, S Jiang, EA Guzmán, BN Scissors, C Tuchinda, H He, ... Pigment cell & melanoma research 22 (3), 307-318, 2009 | 42 | 2009 |
Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol I Paterson, GJ Naylor, NM Gardner, E Guzmán, AE Wright Chemistry–An Asian Journal 6 (2), 459-473, 2011 | 41 | 2011 |
Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites AE Wright, KB Killday, D Chakrabarti, EA Guzmán, D Harmody, ... Marine drugs 15 (1), 16, 2017 | 39 | 2017 |
Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin I Paterson, GJ Naylor, T Fujita, E Guzmán, AE Wright Chemical communications 46 (2), 261-263, 2010 | 39 | 2010 |
Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits … EA Guzmán, Q Xu, TP Pitts, KO Mitsuhashi, C Baker, PA Linley, ... International journal of cancer 139 (9), 2116-2126, 2016 | 37 | 2016 |
Local cytokine levels associated with delayed-type hypersensitivity responses: modulation by gender, ovariectomy, and estrogen replacement LJ Ma, EA Guzmán, A DeGuzman, HK Muller, AM Walker, LB Owen Journal of Endocrinology 193 (2), 291-297, 2007 | 35 | 2007 |
Comparison of broadband UVB, narrowband UVB, broadband UVA and UVA1 on activation of apoptotic pathways in human peripheral blood mononuclear cells C Tuchinda, HW Lim, FM Strickland, EA Guzmán, HK Wong Photodermatology, Photoimmunology & Photomedicine 23 (1), 2-9, 2007 | 35 | 2007 |
Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima PL Winder, HL Baker, P Linley, EA Guzmán, SA Pomponi, MC Diaz, ... Bioorganic & medicinal chemistry 19 (22), 6599-6603, 2011 | 32 | 2011 |
Isolation, Synthesis, and Biological Activity of Aphrocallistin, an Adenine-Substituted Bromotyramine Metabolite from the Hexactinellida Sponge Aphrocallistes beatrix AE Wright, GP Roth, JK Hoffman, DB Divlianska, D Pechter, SH Sennett, ... Journal of natural products 72 (6), 1178-1183, 2009 | 31 | 2009 |
Dynamics of microcystins and saxitoxin in the Indian River Lagoon, Florida AE Laureano-Rosario, M McFarland, DJ Bradshaw II, J Metz, RA Brewton, ... Harmful Algae 103, 102012, 2021 | 29 | 2021 |
Total synthesis and biological evaluation of novel C2–C6 region analogues of dictyostatin I Paterson, NM Gardner, E Guzmán, AE Wright Bioorganic & medicinal chemistry 17 (6), 2282-2289, 2009 | 29 | 2009 |
Regulated cell death signaling pathways and marine natural products that target them EA Guzmán Marine Drugs 17 (2), 76, 2019 | 27 | 2019 |