Characterization of a polymorphism in NAD (P) H: quinone oxidoreductase (DT-diaphorase) RD Traver, D Siegel, HD Beall, RM Phillips, NW Gibson, WA Franklin, ... British journal of cancer 75 (1), 69-75, 1997 | 396 | 1997 |
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents CW Wright, J Addae-Kyereme, AG Breen, JE Brown, MF Cox, SL Croft, ... Journal of medicinal chemistry 44 (19), 3187-3194, 2001 | 273 | 2001 |
Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs RM Phillips Cancer chemotherapy and pharmacology 77 (3), 441-457, 2016 | 250 | 2016 |
Measles virus causes immunogenic cell death in human melanoma OG Donnelly, F Errington-Mais, L Steele, E Hadac, V Jennings, K Scott, ... Gene therapy 20 (1), 7-15, 2013 | 213 | 2013 |
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study MR Albertella, PM Loadman, PH Jones, RM Phillips, R Rampling, ... Clinical cancer research 14 (4), 1096-1104, 2008 | 151 | 2008 |
Rhodium, iridium, and ruthenium half-sandwich picolinamide complexes as anticancer agents Z Almodares, SJ Lucas, BD Crossley, AM Basri, CM Pask, AJ Hebden, ... Inorganic Chemistry 53 (2), 727-736, 2014 | 149 | 2014 |
Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies. D Ross, H Beall, RD Traver, D Siegel, RM Phillips, NW Gibson Oncology research 6 (10-11), 493-500, 1994 | 146 | 1994 |
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD (H)-dependent and (ii) p53-independent pathways SJ Allison, JRP Knight, C Granchi, R Rani, F Minutolo, J Milner, ... Oncogenesis 3 (5), e102-e102, 2014 | 140 | 2014 |
Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action O Onyeibor, SL Croft, HI Dodson, M Feiz-Haddad, H Kendrick, ... Journal of medicinal chemistry 48 (7), 2701-2709, 2005 | 137 | 2005 |
A critical appraisal of the predictive value of in vitro chemosensitivity assays RM Phillips, MC Bibby, JA Double JNCI: Journal of the National Cancer Institute 82 (18), 1457-1468, 1990 | 137 | 1990 |
Development and characterization of a microfluidic model of the tumour microenvironment JM Ayuso, M Virumbrales-Muñoz, A Lacueva, PM Lanuza, ... Scientific reports 6 (1), 36086, 2016 | 129 | 2016 |
Asymmetric triplex metallohelices with high and selective activity against cancer cells AD Faulkner, RA Kaner, QMA Abdallah, G Clarkson, DJ Fox, P Gurnani, ... Nature Chemistry 6 (9), 797-803, 2014 | 120 | 2014 |
Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours RM Phillips, PM Loadman, BP Cronin British journal of cancer 77 (12), 2112-2119, 1998 | 105 | 1998 |
Cannabinoid pharmacology in cancer research: A new hope for cancer patients? FA Javid, RM Phillips, S Afshinjavid, R Verde, A Ligresti European journal of pharmacology 775, 1-14, 2016 | 104 | 2016 |
Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids KM Nicholson, MC Bibby, RM Phillips European Journal of Cancer 33 (8), 1291-1298, 1997 | 104 | 1997 |
Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands DCF Monteiro, RM Phillips, BD Crossley, J Fielden, CE Willans Dalton Transactions 41 (13), 3720-3725, 2012 | 97 | 2012 |
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies A Evans, V Bates, H Troy, S Hewitt, S Holbeck, YL Chung, R Phillips, ... Cancer chemotherapy and pharmacology 61, 377-393, 2008 | 97 | 2008 |
Synthesis of iridium and ruthenium complexes with (N, N),(N, O) and (O, O) coordinating bidentate ligands as potential anti-cancer agents SJ Lucas, RM Lord, RL Wilson, RM Phillips, V Sridharan, PC McGowan Dalton Transactions 41 (45), 13800-13802, 2012 | 92 | 2012 |
Expression of HIF-1α and Glut-1 in human bladder cancer V Palit, RM Phillips, R Puri, T Shah, MC Bibby Oncology reports 14 (4), 909-913, 2005 | 92 | 2005 |
Synthesis and anticancer activity of silver (I)–N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine HA Mohamed, BRM Lake, T Laing, RM Phillips, CE Willans Dalton Transactions 44 (16), 7563-7569, 2015 | 91 | 2015 |