| Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 165 | 2019 |
| Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ... Molecular Therapy 26 (10), 2431-2442, 2018 | 112 | 2018 |
| Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards RM Martin, JL Fowler, MK Cromer, BJ Lesch, E Ponce, N Uchida, ... Nature communications 11 (1), 2713, 2020 | 84 | 2020 |
| Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ... Nature medicine 27 (4), 677-687, 2021 | 65 | 2021 |
| Metabolic engineering generates a transgene-free safety switch for cell therapy V Wiebking, JO Patterson, R Martin, MK Chanda, CM Lee, W Srifa, G Bao, ... Nature Biotechnology 38 (12), 1441-1450, 2020 | 45 | 2020 |
| Efficient scarless genome editing in human pluripotent stem cells K Ikeda, N Uchida, T Nishimura, J White, RM Martin, H Nakauchi, ... Nature Methods 15 (12), 1045-1047, 2018 | 36 | 2018 |
| CRISPR/Cas9 genome engineering in engraftable human brain-derived neural stem cells DP Dever, SG Scharenberg, J Camarena, EJ Kildebeck, JT Clark, ... Iscience 15, 524-535, 2019 | 32 | 2019 |
| Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells BB Madison, D Patil, M Richter, X Li, M Tong, S Cranert, X Wang, R Martin, ... Molecular Therapy-Nucleic Acids 29, 979-995, 2022 | 24 | 2022 |
| Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses LT Ang, AT Nguyen, KJ Liu, A Chen, X Xiong, M Curtis, RM Martin, ... Cell 185 (14), 2523-2541. e30, 2022 | 22 | 2022 |
| Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells T Nishimura, H Xu, M Iwasaki, D Karigane, B Saavedra, Y Takahashi, ... Gene Therapy 27 (10), 525-534, 2020 | 12 | 2020 |
| Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6 RM Martin, K Ikeda, N Uchida, K Cromer, T Nishimura, DP Dever, ... BioRxiv, 252163, 2018 | 7 | 2018 |
| An unusual “OR” gate for allosteric regulation of mammalian transglutaminase 2 in the extracellular matrix AV Melkonian, E Loppinet, R Martin, M Porteus, C Khosla Journal of the American Chemical Society 143 (28), 10537-10540, 2021 | 5 | 2021 |
| Differential role of natural killer group 2D in recognition and cytotoxicity of hepatocyte-like cells derived from embryonic stem cells and induced pluripotent stem cells T Cisneros, DW Dillard, X Qu, J Arredondo-Guerrero, M Castro, ... American Journal of Transplantation 19 (6), 1652-1662, 2019 | 4 | 2019 |
| COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS J Rychak, S Essex, M Butcher, P Griffin, B Madison, R Martin, N Parayath, ... US Patent App. 18/263,793, 2024 | | 2024 |
| Genetically modified induced pluripotent stem cells and methods of use thereof R Martin, BB Madison, XI Haibin US Patent App. 18/264,782, 2024 | | 2024 |
| Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes in R6/2 mice DA Simmons, S Selvaraj, T Chen, G Cao, T Sauto Camelo, TLM McHugh, ... bioRxiv, 2024.05. 01.592095, 2024 | | 2024 |
| Orthogonal safety switches to eliminate genetically engineered cells MH Porteus, MK Cromer, R Martin, J Fowler, K Loh US Patent App. 17/904,075, 2023 | | 2023 |
| Developing Tools for Pluripotent Stem Cell-Based Therapies Using AAV6/CAS9-Mediated Genome Editing RM Martin Stanford University, 2020 | | 2020 |
| Targeting beta-Globin Gene into alpha-Globin Locus in Human Hematopoietic Stem and Progenitor Cells MK Cromer, J Camarena, RM Martin, BJ Lesch, VT Lemgart, RO Bak, ... MOLECULAR THERAPY 27 (4), 400-400, 2019 | | 2019 |
| Can't Live without" U": Genetic Engineering of UMPS to Create Auxotrophy in Human Cells V Wiebking, JO Patterson, R Martin, MK Chanda, CM Lee, W Srifa, G Bao, ... MOLECULAR THERAPY 27 (4), 454-454, 2019 | | 2019 |
Matthew PorteusProfessor of Pediatrics, Stanford University在 stanford.edu 的电子邮件经过验证
