Current NMR techniques for structure-based drug discovery T Sugiki, K Furuita, T Fujiwara, C Kojima Molecules 23 (1), 148, 2018 | 159 | 2018 |
Impact of membrane curvature on amyloid aggregation MS Terakawa, Y Lin, M Kinoshita, S Kanemura, D Itoh, T Sugiki, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1741-1764, 2018 | 123 | 2018 |
Modern technologies of solution nuclear magnetic resonance spectroscopy for three-dimensional structure determination of proteins open avenues for life scientists T Sugiki, N Kobayashi, T Fujiwara Computational and structural biotechnology journal 15, 328-339, 2017 | 112 | 2017 |
Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT) T Sugiki, K Takeuchi, T Yamaji, T Takano, Y Tokunaga, K Kumagai, ... Journal of Biological Chemistry 287 (40), 33706-33718, 2012 | 68 | 2012 |
Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells Y Taketomi, T Sugiki, T Saito, S Ishii, M Hisada, T Suzuki-Nishimura, ... Biochemical and biophysical research communications 306 (2), 339-346, 2003 | 63 | 2003 |
Model membrane size-dependent amyloidogenesis of Alzheimer's amyloid-β peptides M Kinoshita, E Kakimoto, MS Terakawa, Y Lin, T Ikenoue, M So, T Sugiki, ... Physical Chemistry Chemical Physics 19 (24), 16257-16266, 2017 | 50 | 2017 |
N-myc downregulated gene 1 is a phosphorylated protein in mast cells T Sugiki, M Murakami, Y Taketomi, R Kikuchi-Yanoshita, I Kudo Biological and Pharmaceutical Bulletin 27 (5), 624-627, 2004 | 46 | 2004 |
Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells T Sugiki, Y Taketomi, R Kikuchi-Yanoshita, M Murakami, I Kudo Biological and Pharmaceutical Bulletin 27 (5), 628-633, 2004 | 43 | 2004 |
Isotopic Labeling of Heterologous Proteins in the Yeast Pichia pastoris and Kluyveromyces lactis T Sugiki, O Ichikawa, M Miyazawa-Onami, I Shimada, H Takahashi Protein NMR techniques, 19-36, 2012 | 42 | 2012 |
Latest approaches for efficient protein production in drug discovery T Sugiki, T Fujiwara, C Kojima Expert opinion on drug discovery 9 (10), 1189-1204, 2014 | 41 | 2014 |
The crystal structure of the plant small GTPase OsRac1 reveals its mode of binding to NADPH oxidase K Kosami, I Ohki, M Nagano, K Furuita, T Sugiki, Y Kawano, T Kawasaki, ... Journal of Biological Chemistry 289 (41), 28569-28578, 2014 | 40 | 2014 |
Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-beta T Sugiki Biochemical and biophysical research communications 441 (2), 493-498, 2013 | 40 | 2013 |
Membrane-induced initial structure of α-synuclein control its amyloidogenesis on model membranes MS Terakawa, YH Lee, M Kinoshita, Y Lin, T Sugiki, N Fukui, T Ikenoue, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (3), 757-766, 2018 | 38 | 2018 |
Perdeuteration and methyl-selective 1H, 13C-labeling by using a Kluyveromyces lactis expression system M Miyazawa-Onami, K Takeuchi, T Takano, T Sugiki, I Shimada, ... Journal of biomolecular NMR 57, 297-304, 2013 | 38 | 2013 |
Diverse structural conversion and aggregation pathways of Alzheimerʼs amyloid-β (1–40) Y Lin, BR Sahoo, D Ozawa, M Kinoshita, J Kang, MH Lim, M Okumura, ... ACS nano 13 (8), 8766-8783, 2019 | 35 | 2019 |
Robust folding of a de novo designed ideal protein even with most of the core mutated to valine R Koga, M Yamamoto, T Kosugi, N Kobayashi, T Sugiki, T Fujiwara, ... Proceedings of the National Academy of Sciences 117 (49), 31149-31156, 2020 | 31 | 2020 |
Amorphous aggregation of cytochrome c with inherently low amyloidogenicity is characterized by the metastability of supersaturation and the phase diagram Y Lin, K Ishimori, Y Goto, YH Lee Biophysical Journal 110 (3), 399a, 2016 | 27 | 2016 |
Stable isotope labeling of protein by Kluyveromyces lactis for NMR study T Sugiki, I Shimada, H Takahashi Journal of biomolecular NMR 42, 159-162, 2008 | 26 | 2008 |
Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif T Sugiki, D Egawa, K Kumagai, C Kojima, T Fujiwara, K Takeuchi, ... Journal of Biological Chemistry 293 (28), 11206-11217, 2018 | 25 | 2018 |
Real-time assay method of lipid extraction activity T Sugiki, H Takahashi, M Nagasu, K Hanada, I Shimada Analytical biochemistry 399 (2), 162-167, 2010 | 23 | 2010 |