β-cell replication is the primary mechanism subserving the postnatal expansion of β-cell mass in humans JJ Meier, AE Butler, Y Saisho, T Monchamp, R Galasso, A Bhushan, ... Diabetes 57 (6), 1584-1594, 2008 | 807 | 2008 |
β cell replication is the primary mechanism for maintaining postnatal β cell mass S Georgia, A Bhushan The Journal of clinical investigation 114 (7), 963-968, 2004 | 670 | 2004 |
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? JJ Meier, A Bhushan, AE Butler, RA Rizza, PC Butler Diabetologia 48, 2221-2228, 2005 | 651 | 2005 |
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis A Bhushan, N Itoh, S Kato, JP Thiery, P Czernichow, S Bellusci, ... Oxford University Press for The Company of Biologists Limited 128 (24), 5109 …, 2001 | 591 | 2001 |
Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells GG Nair, JS Liu, HA Russ, S Tran, MS Saxton, R Chen, C Juang, M Li, ... Nature cell biology 21 (2), 263-274, 2019 | 423 | 2019 |
Age-dependent decline in β-cell proliferation restricts the capacity of β-cell regeneration in mice SI Tschen, S Dhawan, T Gurlo, A Bhushan Diabetes 58 (6), 1312-1320, 2009 | 389 | 2009 |
The replication of β cells in normal physiology, in disease and for therapy PC Butler, JJ Meier, AE Butler, A Bhushan Nature clinical practice Endocrinology & metabolism 3 (11), 758-768, 2007 | 371 | 2007 |
Targeted elimination of senescent beta cells prevents type 1 diabetes PJ Thompson, A Shah, V Ntranos, F Van Gool, M Atkinson, A Bhushan Cell metabolism 29 (5), 1045-1060. e10, 2019 | 299 | 2019 |
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx S Dhawan, S Georgia, S Tschen, G Fan, A Bhushan Developmental cell 20 (4), 419-429, 2011 | 285 | 2011 |
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic β-cell proliferation S Dhawan, SI Tschen, A Bhushan Genes & development 23 (8), 906-911, 2009 | 259 | 2009 |
Nkx2. 2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming JB Papizan, RA Singer, SI Tschen, S Dhawan, JM Friel, SB Hipkens, ... Genes & development 25 (21), 2291-2305, 2011 | 233 | 2011 |
Smad8 mediates the signaling of the receptor serine kinase Y Chen, A Bhushan, W Vale Proceedings of the National Academy of Sciences 94 (24), 12938-12943, 1997 | 213 | 1997 |
p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors S Georgia, R Soliz, M Li, P Zhang, A Bhushan Developmental biology 298 (1), 22-31, 2006 | 190 | 2006 |
RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex I Bach, C Rodriguez-Esteban, C Carrière, A Bhushan, A Krones, ... Nature genetics 22 (4), 394-399, 1999 | 183 | 1999 |
DNA methylation directs functional maturation of pancreatic β cells S Dhawan, SI Tschen, C Zeng, T Guo, M Hebrok, A Matveyenko, ... The Journal of clinical investigation 125 (7), 2851-2860, 2015 | 166 | 2015 |
Human β-cell proliferation and intracellular signaling: part 3 AF Stewart, MA Hussain, A García-Ocaña, RC Vasavada, A Bhushan, ... Diabetes 64 (6), 1872-1885, 2015 | 164 | 2015 |
Inhibition of TGF-β signaling promotes human pancreatic β-cell replication S Dhawan, E Dirice, RN Kulkarni, A Bhushan Diabetes 65 (5), 1208-1218, 2016 | 126 | 2016 |
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation AER Kartikasari, JX Zhou, MS Kanji, DN Chan, A Sinha, A Grapin‐Botton, ... The EMBO journal 32 (10), 1393-1408, 2013 | 122 | 2013 |
mTORC1-to-AMPK switching underlies β cell metabolic plasticity during maturation and diabetes R Jaafar, S Tran, AN Shah, G Sun, M Valdearcos, P Marchetti, M Masini, ... The Journal of clinical investigation 129 (10), 4124-4137, 2019 | 113 | 2019 |
p27 regulates the transition of β-cells from quiescence to proliferation S Georgia, A Bhushan Diabetes 55 (11), 2950-2956, 2006 | 112 | 2006 |