PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells C Blank, I Brown, AC Peterson, M Spiotto, Y Iwai, T Honjo, TF Gajewski Cancer research 64 (3), 1140-1145, 2004 | 1028 | 2004 |
Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy K Lu, C He, N Guo, C Chan, K Ni, G Lan, H Tang, C Pelizzari, YX Fu, ... Nature biomedical engineering 2 (8), 600-610, 2018 | 456 | 2018 |
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells B Zhang, NA Bowerman, JK Salama, H Schmidt, MT Spiotto, ... The Journal of experimental medicine 204 (1), 49-55, 2007 | 407 | 2007 |
Bystander elimination of antigen loss variants in established tumors MT Spiotto, DA Rowley, H Schreiber Nature medicine 10 (3), 294-298, 2004 | 314 | 2004 |
Increasing tumor antigen expression overcomes “ignorance” to solid tumors via crosspresentation by bone marrow-derived stromal cells MT Spiotto, P Yu, DA Rowley, MI Nishimura, SC Meredith, TF Gajewski, ... Immunity 17 (6), 737-747, 2002 | 313 | 2002 |
Characterization of the role of IL‐6 in the progression of prostate cancer TDK Chung, JJ Yu, MT Spiotto, M Bartkowski, JW Simons The Prostate 38 (3), 199-207, 1999 | 289 | 1999 |
STAT3 mediates IL‐6‐induced neuroendocrine differentiation in prostate cancer cells MT Spiotto, TDK Chung The Prostate 42 (3), 186-195, 2000 | 212 | 2000 |
STAT3 mediates IL‐6‐induced growth inhibition in the human prostate cancer cell line LNCaP MT Spiotto, TDK Chung The Prostate 42 (2), 88-98, 2000 | 180 | 2000 |
The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications M Spiotto, YX Fu, RR Weichselbaum Science immunology 1 (3), eaag1266-eaag1266, 2016 | 173 | 2016 |
Radiotherapy after prostatectomy: improved biochemical relapse-free survival with whole pelvic compared with prostate bed only for high-risk patients MT Spiotto, SL Hancock, CR King International Journal of Radiation Oncology* Biology* Physics 69 (1), 54-61, 2007 | 171 | 2007 |
Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways DR Fels, J Ye, AT Segan, SJ Kridel, M Spiotto, M Olson, AC Koong, ... Cancer research 68 (22), 9323-9330, 2008 | 165 | 2008 |
Improved outcomes with higher doses for salvage radiotherapy after prostatectomy CR King, MT Spiotto International Journal of Radiation Oncology* Biology* Physics 71 (1), 23-27, 2008 | 145 | 2008 |
Interleukin‐6 activates phosphatidylinositol‐3 kinase, which inhibits apoptosis in human prostate cancer cell lines TDK Chung, JJ Yu, TA Kong, MT Spiotto, JM Lin The Prostate 42 (1), 1-7, 2000 | 135 | 2000 |
Complementary Role of CD4+ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8+ T Cells P Yu, MT Spiotto, Y Lee, H Schreiber, YX Fu The Journal of experimental medicine 197 (8), 985-995, 2003 | 119 | 2003 |
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth MT Spiotto, A Banh, I Papandreou, H Cao, MG Galvez, GC Gurtner, ... Cancer research 70 (1), 78-88, 2010 | 106 | 2010 |
Machine learning–guided adjuvant treatment of head and neck cancer FM Howard, S Kochanny, M Koshy, M Spiotto, AT Pearson JAMA network Open 3 (11), e2025881-e2025881, 2020 | 93 | 2020 |
Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer VM Villaflor, JM Melotek, TG Karrison, RJ Brisson, EA Blair, L Portugal, ... Annals of Oncology 27 (5), 908-913, 2016 | 86 | 2016 |
Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells MT Spiotto, H Schreiber Cancer immunity 5 (1), 2005 | 81 | 2005 |
Differences in survival with surgery and postoperative radiotherapy compared with definitive chemoradiotherapy for oral cavity cancer: a national cancer database analysis MT Spiotto, G Jefferson, B Wenig, M Markiewicz, RR Weichselbaum, ... JAMA Otolaryngology–Head & Neck Surgery 143 (7), 691-699, 2017 | 74 | 2017 |
Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance W Zheng, KB Skowron, JP Namm, B Burnette, C Fernandez, A Arina, ... Oncotarget 7 (28), 43039, 2016 | 72 | 2016 |