| The target landscape of clinical kinase drugs S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ... Science 358 (6367), eaan4368, 2017 | 778 | 2017 |
| Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS Y Bian, R Zheng, FP Bayer, C Wong, YC Chang, C Meng, DP Zolg, ... Nature communications 11 (1), 157, 2020 | 295 | 2020 |
| Optimized chemical proteomics assay for kinase inhibitor profiling G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ... Journal of proteome research 14 (3), 1574-1586, 2015 | 141 | 2015 |
| Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors S Klaeger, B Gohlke, J Perrin, V Gupta, S Heinzlmeir, D Helm, H Qiao, ... ACS chemical biology 11 (5), 1245-1254, 2016 | 98 | 2016 |
| PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase B Adhikari, J Bozilovic, M Diebold, JD Schwarz, J Hofstetter, M Schröder, ... Nature chemical biology 16 (11), 1179-1188, 2020 | 95 | 2020 |
| The formation of a camalexin biosynthetic metabolon S Mucha, S Heinzlmeir, V Kriechbaumer, B Strickland, C Kirchhelle, ... The Plant Cell 31 (11), 2697-2710, 2019 | 70 | 2019 |
| Proteome activity landscapes of tumor cell lines determine drug responses M Frejno, C Meng, B Ruprecht, T Oellerich, S Scheich, K Kleigrewe, ... Nature communications 11 (1), 3639, 2020 | 61 | 2020 |
| Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs S Heinzlmeir, D Kudlinzki, S Sreeramulu, S Klaeger, SL Gande, V Linhard, ... ACS chemical biology 11 (12), 3400-3411, 2016 | 55 | 2016 |
| Pharmacoproteomic characterisation of human colon and rectal cancer M Frejno, R Zenezini Chiozzi, M Wilhelm, H Koch, R Zheng, S Klaeger, ... Molecular systems biology 13 (11), 951, 2017 | 54 | 2017 |
| Design, synthesis, and evaluation of WD-repeat-containing protein 5 (WDR5) degraders A Dölle, B Adhikari, A Krämer, J Weckesser, N Berner, LM Berger, ... Journal of medicinal chemistry 64 (15), 10682-10710, 2021 | 52 | 2021 |
| Evaluation of kinase activity profiling using chemical proteomics B Ruprecht, J Zecha, S Heinzlmeir, G Medard, S Lemeer, B Kuster ACS chemical biology 10 (12), 2743-2752, 2015 | 41 | 2015 |
| Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A B Hoermann, T Kokot, D Helm, S Heinzlmeir, JE Chojnacki, T Schubert, ... Nature Communications 11 (1), 3583, 2020 | 40 | 2020 |
| DENEDDYLASE1 Deconjugates NEDD8 from Non-Cullin Protein Substrates in Arabidopsis thaliana J Mergner, S Heinzlmeir, B Kuster, C Schwechheimer The Plant Cell 27 (3), 741-753, 2015 | 38 | 2015 |
| Decrypting drug actions and protein modifications by dose-and time-resolved proteomics J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ... Science 380 (6640), 93-101, 2023 | 35 | 2023 |
| Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib RC Montenegro, A Howarth, A Ceroni, V Fedele, B Farran, FP Mesquita, ... Oncotarget 11 (5), 535, 2020 | 30 | 2020 |
| Chemoproteomic selectivity profiling of PIKK and PI3K kinase inhibitors M Reinecke, B Ruprecht, S Poser, S Wiechmann, M Wilhelm, ... ACS Chemical Biology 14 (4), 655-664, 2019 | 27 | 2019 |
| NVP‐BHG712: Effects of regioisomers on the affinity and selectivity toward the EPHrin family A Tröster, S Heinzlmeir, BT Berger, SL Gande, K Saxena, S Sreeramulu, ... ChemMedChem 13 (16), 1629-1633, 2018 | 27 | 2018 |
| Increased pancreatic protease activity in response to antibiotics impairs gut barrier and triggers colitis H Yoon, M Schaubeck, I Lagkouvardos, A Blesl, S Heinzlmeir, H Hahne, ... Cellular and Molecular Gastroenterology and Hepatology 6 (3), 370-388. e3, 2018 | 27 | 2018 |
| Chemoproteomics‐aided medicinal chemistry for the discovery of EPHA2 inhibitors S Heinzlmeir, J Lohse, T Treiber, D Kudlinzki, V Linhard, SL Gande, ... ChemMedChem 12 (12), 999-1011, 2017 | 27 | 2017 |
| New affinity probe targeting VEGF receptors for kinase inhibitor selectivity profiling by chemical proteomics X Ku, S Heinzlmeir, D Helm, G Médard, B Kuster Journal of proteome research 13 (5), 2445-2452, 2014 | 23 | 2014 |
