Design of a 20-amino acid, three-stranded β-sheet protein T Kortemme, M Ramı́rez-Alvarado, L Serrano Science 281 (5374), 253-256, 1998 | 427 | 1998 |
ThT 101: a primer on the use of thioflavin T to investigate amyloid formation K Gade Malmos, LM Blancas-Mejia, B Weber, J Buchner, ... Amyloid 24 (1), 1-16, 2017 | 370 | 2017 |
De novo design and structural analysis of a model β-hairpin peptide system M Ramírez-Alvarado, FJ Blanco, L Serrano Nature structural biology 3 (7), 604-612, 1996 | 364 | 1996 |
A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy R Khurana, C Ionescu-Zanetti, M Pope, J Li, L Nielson, ... Biophysical journal 85 (2), 1135-1144, 2003 | 358 | 2003 |
A systematic exploration of the influence of the protein stability on amyloid fibril formation in vitro M Ramírez-Alvarado, JS Merkel, L Regan Proceedings of the National Academy of Sciences 97 (16), 8979-8984, 2000 | 275 | 2000 |
Systemic amyloidoses LM Blancas-Mejía, M Ramirez-Alvarado Annual review of biochemistry 82, 745-774, 2013 | 249 | 2013 |
Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features S Kumar, A Dispenzieri, JA Katzmann, DR Larson, CL Colby, MQ Lacy, ... Blood, The Journal of the American Society of Hematology 116 (24), 5126-5129, 2010 | 201 | 2010 |
Formation and stability of β-hairpin structures in polypeptides F Blanco, M Ramírez-Alvarado, L Serrano Current opinion in structural biology 8 (1), 107-111, 1998 | 189 | 1998 |
Role of β-turn residues in β-hairpin formation and stability in designed peptides M Ramı́rez-Alvarado, FJ Blanco, H Niemann, L Serrano Journal of molecular biology 273 (4), 898-912, 1997 | 158 | 1997 |
β-Hairpin and β-sheet formation in designed linear peptides M Ramı́rez-Alvarado, T Kortemme, FJ Blanco, L Serrano Bioorganic & medicinal chemistry 7 (1), 93-103, 1999 | 150 | 1999 |
Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation L Wang, TV Nguyen, RW McLaughlin, LA Sikkink, M Ramirez-Alvarado, ... Proceedings of the National Academy of Sciences 102 (26), 9394-9399, 2005 | 125 | 2005 |
Altered dimer interface decreases stability in an amyloidogenic protein EM Baden, BAL Owen, FC Peterson, BF Volkman, M Ramirez-Alvarado, ... Journal of Biological Chemistry 283 (23), 15853-15860, 2008 | 124 | 2008 |
Clarifying immunoglobulin gene usage in systemic and localized immunoglobulin light-chain amyloidosis by mass spectrometry TV Kourelis, S Dasari, JD Theis, M Ramirez-Alvarado, PJ Kurtin, MA Gertz, ... Blood, The Journal of the American Society of Hematology 129 (3), 299-306, 2017 | 122 | 2017 |
Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23 A Chadli, SJ Felts, Q Wang, WP Sullivan, MV Botuyan, A Fauq, ... Journal of biological chemistry 285 (6), 4224-4231, 2010 | 112 | 2010 |
Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis TL Poshusta, LA Sikkink, N Leung, RJ Clark, A Dispenzieri, ... PloS one 4 (4), e5169, 2009 | 103 | 2009 |
Computer-aided design of β-sheet peptides M López, E Lacroix, M Ramı́rez-Alvarado, L Serrano Journal of molecular biology 312 (1), 229-246, 2001 | 100 | 2001 |
Evaluation of the BH3-only protein Puma as a direct Bak activator H Dai, YP Pang, M Ramirez-Alvarado, SH Kaufmann Journal of Biological Chemistry 289 (1), 89-99, 2014 | 98 | 2014 |
In vivo targeting of antibody fragments to the nervous system for Alzheimer’s disease immunotherapy and molecular imaging of amyloid plaques JF Poduslo, M Ramakrishnan, SS Holasek, M Ramirez‐Alvarado, ... Journal of neurochemistry 102 (2), 420-433, 2007 | 97 | 2007 |
The effects of sodium sulfate, glycosaminoglycans, and Congo red on the structure, stability, and amyloid formation of an immunoglobulin light‐chain protein RW Mclaughlin, JK De Stigter, LA Sikkink, EM Baden, ... Protein science 15 (7), 1710-1722, 2006 | 91 | 2006 |
Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy–related kidney diseases N Leung, M Gertz, RA Kyle, FC Fervenza, MV Irazabal, A Eirin, S Kumar, ... Clinical Journal of the American Society of Nephrology 7 (12), 1964-1968, 2012 | 89 | 2012 |